Brain-derived extracellular vesicles mediated coagulopathy, inflammation and apoptosis after sepsis

Glioblastoma cell populations with distinct oncogenic programs release podoplanin as procoagulant extracellular vesicles

(2021) Nadim Tawil et al.   Blood Advances

Coagulopathy and sepsis: Pathophysiology, clinical manifestations and treatment

(2021) Michela Giustozzi et al.   BLOOD REVIEWS

Blood-borne and brain-derived microparticles in morphine-induced anti-nociceptive tolerance

(2020) Deepa Ruhela et al.   BRAIN BEHAVIOR AND IMMUNITY

TMEM173 Drives Lethal Coagulation in Sepsis

(2020) Hui Zhang et al.   Cell Host & Microbe

Myricetin ameliorates sepsis-associated acute lung injury in a murine sepsis model

(2020) Haibo Xu et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

Toll‐like receptors 2 and 7 mediate coagulation activation and coagulopathy in murine sepsis

(2019) Brittney Williams et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Diagnosis and management of sepsis‐induced coagulopathy and disseminated intravascular coagulation

(2019) Toshiaki Iba et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Role of disseminated intravascular coagulation in severe sepsis

(2019) Satoshi Gando et al.   THROMBOSIS RESEARCH

Tissue-Specific Macrophage Responses to Remote Injury Impact the Outcome of Subsequent Local Immune Challenge

(2019) Friedrich Felix Hoyer et al.   IMMUNITY

Brain-Derived Microparticles (BDMPs) Contribute to Neuroinflammation and Lactadherin Reduces BDMP Induced Neuroinflammation and Improves Outcome After Stroke

(2019) Zhili Chen et al.   Frontiers in Immunology

Nanoparticle-induced neutrophil apoptosis increases survival in sepsis and alleviates neurological damage in stroke

(2019) Can Yang Zhang et al.   Science Advances

Flavonoid fisetin alleviates kidney inflammation and apoptosis via inhibiting Src-mediated NF-κB p65 and MAPK signaling pathways in septic AKI mice

(2019) Qian Ren et al.   BIOMEDICINE & PHARMACOTHERAPY

Cell-derived Microparticles and Acute Coronary Syndromes: Is there a Predictive Role for Microparticles

(2019) Effimia Zacharia et al.   CURRENT MEDICINAL CHEMISTRY

MicroRNA-30e promotes hepatocyte proliferation and inhibits apoptosis in cecal ligation and puncture-induced sepsis through the JAK/STAT signaling pathway by binding to FOSL2

(2018) Lan Ling et al.   BIOMEDICINE & PHARMACOTHERAPY

Brain-derived microparticles activate microglia/macrophages and induce neuroinflammation

(2018) Hongtao Rong et al.   BRAIN RESEARCH

Sepsis and septic shock

(2018) Maurizio Cecconi et al.   LANCET

Shedding light on the cell biology of extracellular vesicles

(2018) Guillaume van Niel et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Cell-to-cell Communication by Extracellular Vesicles: Focus on Microglia

(2018) Rosa C. Paolicelli et al.   NEUROSCIENCE

Platelet Microparticles Mediate Glomerular Endothelial Injury in Early Diabetic Nephropathy

(2018) Yang Zhang et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Tropisetron inhibits sepsis by repressing hyper-inflammation and regulating the cardiac action potential in rat models

(2018) Zhengjiang Liu et al.   BIOMEDICINE & PHARMACOTHERAPY

Microglial-derived microparticles mediate neuroinflammation after traumatic brain injury

(2017) Alok Kumar et al.   Journal of Neuroinflammation

Different Potential of Extracellular Vesicles to Support Thrombin Generation: Contributions of Phosphatidylserine, Tissue Factor, and Cellular Origin

(2017) Carla Tripisciano et al.   Scientific Reports

Cellular microparticles and pathophysiology of traumatic brain injury

(2017) Zilong Zhao et al.   Protein & Cell

Assessment of Global Incidence and Mortality of Hospital-treated Sepsis. Current Estimates and Limitations

(2016) Carolin Fleischmann et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Cardiolipin-mediated procoagulant activity of mitochondria contributes to traumatic brain injury-associated coagulopathy in mice

(2016) Z. Zhao et al.   BLOOD

Incidence of severe sepsis and septic shock in German intensive care units: the prospective, multicentre INSEP study

(2016)   INTENSIVE CARE MEDICINE

The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3)

(2016) Mervyn Singer et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Procoagulant microparticles promote coagulation in a factor XI-dependent manner in human endotoxemia

(2016) M. J. Mooberry et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Impact of Platelets and Platelet-Derived Microparticles on Hypercoagulability Following Burn Injury

(2016) Emily F. Midura et al.   SHOCK

Circulating Microparticles, Blood Cells, and Endothelium Induce Procoagulant Activity in Sepsis Through Phosphatidylserine Exposure

(2016) Yan Zhang et al.   SHOCK

Blocking triggering receptor expressed on myeloid cells-1 attenuates lipopolysaccharide-induced acute lung injury via inhibiting NLRP3 inflammasome activation

(2016) Tian Liu et al.   Scientific Reports

Brain-derived microparticles induce systemic coagulation in a murine model of traumatic brain injury

(2015) Y. Tian et al.   BLOOD

Microparticles: markers and mediators of sepsis-induced microvascular dysfunction, immunosuppression, and AKI

(2015) Ana Carolina P. Souza et al.   KIDNEY INTERNATIONAL

Anticoagulant therapy for sepsis-associated disseminated intravascular coagulation: the view from Japan

(2014) T. Iba et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Leukocyte-Derived Microparticles as Proinflammatory Mediators in Atherosclerosis∗

(2013) Jian-Guo Wang et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Role of microparticles in sepsis

(2012) V.L. Reid et al.   BRITISH JOURNAL OF ANAESTHESIA

Membrane vesicles, current state-of-the-art: emerging role of extracellular vesicles

(2011) Bence György et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Immunodesign of experimental sepsis by cecal ligation and puncture

(2009) Daniel Rittirsch et al.   Nature Protocols