Inhibition of PDIA3 in club cells attenuates osteopontin production and lung fibrosis

Distinct Airway Epithelial Stem Cells Hide among Club Cells but Mobilize to Promote Alveolar Regeneration

(2020) Jaymin J. Kathiriya et al.   Cell Stem Cell

Chronic Hypersensitivity Pneumonitis, an Interstitial Lung Disease with Distinct Molecular Signatures

(2020) Haruhiko Furusawa et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Distinct stem/progenitor cells proliferate to regenerate the trachea, intrapulmonary airways and alveoli in COVID-19 patients

(2020) Yinshan Fang et al.   CELL RESEARCH

Single-cell RNA-seq reveals ectopic and aberrant lung-resident cell populations in idiopathic pulmonary fibrosis

(2020) Taylor S. Adams et al.   Science Advances

Single-cell RNA sequencing reveals profibrotic roles of distinct epithelial and mesenchymal lineages in pulmonary fibrosis

(2020) Arun C. Habermann et al.   Science Advances

The role of CD44 in pathological angiogenesis

(2020) Li Chen et al.   FASEB JOURNAL

Dysregulation of club cell biology in idiopathic pulmonary fibrosis

(2020) Wu-Lin Zuo et al.   PLoS One

XBP1S Regulates MUC5B in a Promoter Variant-Dependent Pathway in IPF Airway Epithelia

(2019) Gang Chen et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Lung epithelial protein disulfide isomerase A3 (PDIA3) plays an important role in influenza infection, inflammation, and airway mechanics

(2019) Nicolas Chamberlain et al.   Redox Biology

Proliferating SPP1/MERTK-expressing macrophages in idiopathic pulmonary fibrosis

(2019) Christina Morse et al.   EUROPEAN RESPIRATORY JOURNAL

The leading role of epithelial cells in the pathogenesis of idiopathic pulmonary fibrosis

(2019) Moisés Selman et al.   CELLULAR SIGNALLING

Endoplasmic reticulum stress in the pathogenesis of fibrotic disease

(2018) Jonathan A. Kropski et al.   JOURNAL OF CLINICAL INVESTIGATION

1α,25-Dihydroxyvitamin D3 and Resolvin D1 Retune the Balance between Amyloid-β Phagocytosis and Inflammation in Alzheimer's Disease Patients

(2018) Mathew T. Mizwicki et al.   JOURNAL OF ALZHEIMERS DISEASE

Expression of mutant Sftpc in murine alveolar epithelia drives spontaneous lung fibrosis

(2018) Shin-Ichi Nureki et al.   JOURNAL OF CLINICAL INVESTIGATION

Depletion of club cells attenuates bleomycin-induced lung injury and fibrosis in mice

(2017) Tetsuya Yokoyama et al.   Journal of Inflammation-London

Osteopontin enhances multi-walled carbon nanotube-triggered lung fibrosis by promoting TGF-β1 activation and myofibroblast differentiation

(2017) Jie Dong et al.   Particle and Fibre Toxicology

Identification and validation of differentially expressed transcripts by RNA-sequencing of formalin-fixed, paraffin-embedded (FFPE) lung tissue from patients with Idiopathic Pulmonary Fibrosis

(2017) Milica Vukmirovic et al.   BMC Pulmonary Medicine

The role of club cell phenoconversion and migration in idiopathic pulmonary fibrosis

(2016) Jutaro Fukumoto et al.   Aging-US

Protein disulfide isomerase–endoplasmic reticulum resident protein 57 regulates allergen-induced airways inflammation, fibrosis, and hyperresponsiveness

(2016) Sidra M. Hoffman et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

LEDGF/p75 Overexpression Attenuates Oxidative Stress-Induced Necrosis and Upregulates the Oxidoreductase ERP57/PDIA3/GRP58 in Prostate Cancer

(2016) Anamika Basu et al.   PLoS One

Protein disulfide isomerase A3–specific Th1 effector cells infiltrate colon cancer tissue of patients with circulating anti–protein disulfide isomerase A3 autoantibodies

(2016) Cristiana Caorsi et al.   Translational Research

Enolase 1 (ENO1) and protein disulfide-isomerase associated 3 (PDIA3) regulate Wnt/ -catenin-driven trans-differentiation of murine alveolar epithelial cells

(2015) K. Mutze et al.   Disease Models & Mechanisms

Small molecule-induced oxidation of protein disulfide isomerase is neuroprotective

(2015) Anna Kaplan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Endoplasmic reticulum stress mediates house dust mite-induced airway epithelial apoptosis and fibrosis

(2013) Sidra M Hoffman et al.   RESPIRATORY RESEARCH

Oxidative Processing of Latent Fas in the Endoplasmic Reticulum Controls the Strength of Apoptosis

(2012) V. Anathy et al.   MOLECULAR AND CELLULAR BIOLOGY

Multiple stromal populations contribute to pulmonary fibrosis without evidence for epithelial to mesenchymal transition

(2011) J. R. Rock et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Conditional Depletion of Airway Progenitor Cells Induces Peribronchiolar Fibrosis

(2010) Anne-Karina T. Perl et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Protein-disulfide Isomerase-associated 3 (Pdia3) Mediates the Membrane Response to 1,25-Dihydroxyvitamin D3in Osteoblasts

(2010) Jiaxuan Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Role of Scgb1a1+ Clara Cells in the Long-Term Maintenance and Repair of Lung Airway, but Not Alveolar, Epithelium

(2009) Emma L. Rawlins et al.   Cell Stem Cell

Clara cell: Progenitor for the bronchiolar epithelium

(2009) Susan D. Reynolds et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

ERp57 Modulates STAT3 Signaling from the Lumen of the Endoplasmic Reticulum

(2009) Helen Coe et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Protein disulphide isomerase family members show distinct substrate specificity: P5 is targeted to BiP client proteins

(2009) C. E. Jessop et al.   JOURNAL OF CELL SCIENCE