Substrate binding modes of purine and pyrimidine nucleotides to human ecto-5′-nucleotidase (CD73) and inhibition by their bisphosphonic acid derivatives
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Title
Substrate binding modes of purine and pyrimidine nucleotides to human ecto-5′-nucleotidase (CD73) and inhibition by their bisphosphonic acid derivatives
Authors
Keywords
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Journal
Purinergic Signalling
Volume -, Issue -, Pages -
Publisher
Springer Science and Business Media LLC
Online
2021-08-17
DOI
10.1007/s11302-021-09802-w
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- (2020) Elizabeth A. Thompson et al. Annual Review of Medicine
- Structure–Activity Relationship of Purine and Pyrimidine Nucleotides as Ecto-5′-Nucleotidase (CD73) Inhibitors
- (2019) Anna Junker et al. JOURNAL OF MEDICINAL CHEMISTRY
- CD73: an emerging checkpoint for cancer immunotherapy
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- Current Developments in Coot for Macromolecular Model Building of Electron Cryo‐microscopy and Crystallographic Data
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- (2016) Ulrike Krug et al. STRUCTURE
- Structures of endothiapepsin–fragment complexes from crystallographic fragment screening using a novel, diverse and affordable 96-compound fragment library
- (2016) Franziska U. Huschmann et al. Acta Crystallographica Section F-Structural Biology Communications
- XDSAPP2.0
- (2016) Karine M. Sparta et al. JOURNAL OF APPLIED CRYSTALLOGRAPHY
- α,β-Methylene-ADP (AOPCP) Derivatives and Analogues: Development of Potent and Selective ecto-5′-Nucleotidase (CD73) Inhibitors
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- Enzymes involved in metabolism of extracellular nucleotides and nucleosides: Functional implications and measurement of activities
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- (2010) N. A. Sowa et al. JOURNAL OF NEUROSCIENCE
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