Cariprazine alleviates core behavioral deficits in the prenatal valproic acid exposure model of autism spectrum disorder

Evaluation of cariprazine in the treatment of bipolar I and II depression

(2020) Lakshmi N. Yatham et al.   INTERNATIONAL CLINICAL PSYCHOPHARMACOLOGY

Disrupted Social Hierarchy in Prenatally Valproate-Exposed Autistic-Like Rats

(2020) Péter Pelsőczi et al.   Frontiers in Behavioral Neuroscience

Symptom improvement in children with autism spectrum disorder following bumetanide administration is associated with decreased GABA/glutamate ratios

(2020) Lingli Zhang et al.   Translational Psychiatry

Autism spectrum disorder

(2020) Catherine Lord et al.   Nature Reviews Disease Primers

Cariprazine Safety in Adolescents and the Elderly: Analyses of Clinical Study Data

(2020) Balázs Szatmári et al.   Frontiers in Psychiatry

Pharmacology profile of F17464, a dopamine D3 receptor preferential antagonist

(2020) Cristina Cosi et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Safety and tolerability of antipsychotic agents in neurodevelopmental disorders: a systematic review

(2020) Felice Iasevoli et al.   Expert Opinion On Drug Safety

Excitation-inhibition balance as a framework for investigating mechanisms in neuropsychiatric disorders

(2019) Vikaas S. Sohal et al.   MOLECULAR PSYCHIATRY

Purkinje cell number-correlated cerebrocerebellar circuit anomaly in the valproate model of autism

(2019) Tamás Spisák et al.   Scientific Reports

The Role of Dopamine D3 Receptor Partial Agonism in Cariprazine-Induced Neurotransmitter Efflux in Rat Hippocampus and Nucleus Accumbens

(2019) Mei Huang et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

The novel antipsychotic cariprazine stabilizes gamma oscillations in rat hippocampal slices

(2019) Maria A. Meier et al.   BRITISH JOURNAL OF PHARMACOLOGY

The valproic acid-induced rodent model of autism

(2018) Chiara Nicolini et al.   EXPERIMENTAL NEUROLOGY

Effects of cariprazine on extracellular levels of glutamate, GABA, dopamine, noradrenaline and serotonin in the medial prefrontal cortex in the rat phencyclidine model of schizophrenia studied by microdialysis and simultaneous recordings of locomotor activity

(2018) Jan Kehr et al.   PSYCHOPHARMACOLOGY

Pharmacological management of behavioral disturbances in children and adolescents with autism spectrum disorders

(2018) Martine Lamy et al.   Current Problems in Pediatric and Adolescent Health Care

Valproic acid induces aberrant development of striatal compartments and corticostriatal pathways in a mouse model of autism spectrum disorder

(2017) Hsiao-Ying Kuo et al.   FASEB JOURNAL

D3 Receptors Regulate Excitability in a Unique Class of Prefrontal Pyramidal Cells

(2017) Rebecca L. Clarkson et al.   JOURNAL OF NEUROSCIENCE

What Is the Male-to-Female Ratio in Autism Spectrum Disorder? A Systematic Review and Meta-Analysis

(2017) Rachel Loomes et al.   JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY

Cariprazine versus risperidone monotherapy for treatment of predominant negative symptoms in patients with schizophrenia: a randomised, double-blind, controlled trial

(2017) György Németh et al.   LANCET

Risperidone and aripiprazole alleviate prenatal valproic acid-induced abnormalities in behaviors and dendritic spine density in mice

(2017) Yuta Hara et al.   PSYCHOPHARMACOLOGY

Modulation of prefrontal cortex excitation/inhibition balance rescues social behavior in CNTNAP2 -deficient mice

(2017) Aslihan Selimbeyoglu et al.   Science Translational Medicine

The dopamine D3 receptor, a quarter century later

(2016) Pierre Sokoloff et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Effects of cariprazine, a novel antipsychotic, on cognitive deficit and negative symptoms in a rodent model of schizophrenia symptomatology

(2016) Jo C. Neill et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

The dopamine D 3 -preferring D 2 /D 3 dopamine receptor partial agonist, cariprazine, reverses behavioural changes in a rat neurodevelopmental model for schizophrenia

(2016) David J.G. Watson et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Reversal of social deficits by subchronic oxytocin in two autism mouse models

(2016) Brian L. Teng et al.   NEUROPHARMACOLOGY

Dopaminergic Neurotransmission in the Nucleus Accumbens Modulates Social Play Behavior in Rats

(2016) Antonia Manduca et al.   NEUROPSYCHOPHARMACOLOGY

Variability of cortical oscillation patterns: A possible endophenotype in autism spectrum disorders?

(2016) Nicole David et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Preferential binding to dopamine D3 over D2 receptors by cariprazine in patients with schizophrenia using PET with the D3/D2 receptor ligand [11C]-(+)-PHNO

(2016) Ragy R. Girgis et al.   PSYCHOPHARMACOLOGY

β-Arrestin-Dependent Dopaminergic Regulation of Calcium Channel Activity in the Axon Initial Segment

(2016) Sungchil Yang et al.   Cell Reports

Lifetime development of behavioural phenotype in the house mouse (Mus musculus)

(2015) Vera Brust et al.   Frontiers in Zoology

Cariprazine in Acute Exacerbation of Schizophrenia

(2015) Suresh Durgam et al.   JOURNAL OF CLINICAL PSYCHIATRY

Perceptual Integration Deficits in Autism Spectrum Disorders Are Associated with Reduced Interhemispheric Gamma-Band Coherence

(2015) I. Peiker et al.   JOURNAL OF NEUROSCIENCE

Exploring the Validity of Valproic Acid Animal Model of Autism

(2015) Darine Froy N. Mabunga et al.   Experimental Neurobiology

Risperidone and the 5-HT2AReceptor Antagonist M100907 Improve Probabilistic Reversal Learning in BTBR T + tf/J Mice

(2014) Dionisio A. Amodeo et al.   Autism Research

γ-band abnormalities as markers of autism spectrum disorders

(2014) Donald C Rojas et al.   Biomarkers in Medicine

The efficacy and tolerability of cariprazine in acute mania associated with bipolar I disorder: a phase II trial

(2014) Suresh Durgam et al.   BIPOLAR DISORDERS

Autistic-Like Syndrome in Mu Opioid Receptor Null Mice is Relieved by Facilitated mGluR4 Activity

(2014) Jérôme AJ Becker et al.   NEUROPSYCHOPHARMACOLOGY

Long-term effects of cariprazine exposure on dopamine receptor subtypes

(2013) Yong Kee Choi et al.   CNS SPECTRUMS

Pharmacotherapy for the Core Symptoms in Autistic Disorder: Current Status of the Research

(2013) Cristan Farmer et al.   DRUGS

The potential role of dopamine D3 receptor neurotransmission in cognition

(2013) Shinichiro Nakajima et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Direct and indirect interactions of the dopamine D3 receptor with glutamate pathways: implications for the treatment of schizophrenia

(2013) Pierre Sokoloff et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

Developmental pathways to autism: A review of prospective studies of infants at risk

(2013) Emily J.H. Jones et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Class I histone deacetylase inhibition ameliorates social cognition and cell adhesion molecule plasticity deficits in a rodent model of autism spectrum disorder

(2012) Andrew G. Foley et al.   NEUROPHARMACOLOGY

Cariprazine, a dopamine D3-receptor-preferring partial agonist, blocks phencyclidine-induced impairments of working memory, attention set-shifting, and recognition memory in the mouse

(2012) Ross Zimnisky et al.   PSYCHOPHARMACOLOGY

Poster #16 CARIPRAZINE, A D3/D2 DOPAMINE RECEPTOR PARTIAL AGONIST ANTIPSYCHOTIC, DISPLAYS GREATER D3 RECEPTOR OCCUPANCY IN VIVO COMPARED WITH OTHER ANTIPSYCHOTICS

(2012) Bela Kiss et al.   SCHIZOPHRENIA RESEARCH

Absence of CNTNAP2 Leads to Epilepsy, Neuronal Migration Abnormalities, and Core Autism-Related Deficits

(2011) Olga Peñagarikano et al.   CELL

Functional potencies of dopamine agonists and antagonists at human dopamine D2 and D3 receptors

(2011) Yoshihiro Tadori et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

In vitro pharmacology of aripiprazole, its metabolite and experimental dopamine partial agonists at human dopamine D2 and D3 receptors

(2011) Yoshihiro Tadori et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Neocortical excitation/inhibition balance in information processing and social dysfunction

(2011) Ofer Yizhar et al.   NATURE

Cariprazine (RGH-188), a potent D3/D2 dopamine receptor partial agonist, binds to dopamine D3 receptors in vivo and shows antipsychotic-like and procognitive effects in rodents

(2011) István Gyertyán et al.   NEUROCHEMISTRY INTERNATIONAL

Dopamine D3-Like Receptors Modulate Anxiety-Like Behavior and Regulate GABAergic Transmission in the Rat Lateral/Basolateral Amygdala

(2011) Marvin R Diaz et al.   NEUROPSYCHOPHARMACOLOGY

Effects of antipsychotics on D3 receptors: A clinical PET study in first episode antipsychotic naive patients with schizophrenia using [11C]-(+)-PHNO

(2011) Romina Mizrahi et al.   SCHIZOPHRENIA RESEARCH

Density and function of central serotonin (5-HT) transporters, 5-HT1A and 5-HT2A receptors, and effects of their targeting on BTBR T+tf/J mouse social behavior

(2010) Georgianna G. Gould et al.   JOURNAL OF NEUROCHEMISTRY

Cariprazine (RGH-188), a Dopamine D3 Receptor-Preferring, D3/D2 Dopamine Receptor Antagonist-Partial Agonist Antipsychotic Candidate: In Vitro and Neurochemical Profile

(2010) B. Kiss et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

The Antipsychotics Olanzapine, Risperidone, Clozapine and Haloperidol Are D2-Selective Ex Vivo but Not In Vitro

(2010) Patrick N McCormick et al.   NEUROPSYCHOPHARMACOLOGY

Fluoxetine but not risperidone increases sociability in the BTBR mouse model of autism

(2010) Kathryn K. Chadman   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

The pleasures of play: pharmacological insights into social reward mechanisms

(2010) Viviana Trezza et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

The Effect of Antipsychotics on the High-Affinity State of D2 and D3 Receptors

(2009) Ariel Graff-Guerrero et al.   ARCHIVES OF GENERAL PSYCHIATRY

Common circuit defect of excitatory-inhibitory balance in mouse models of autism

(2009) Nadine Gogolla et al.   Journal of Neurodevelopmental Disorders

Aripiprazole in the Treatment of Irritability in Children and Adolescents With Autistic Disorder

(2009) R. Owen et al.   PEDIATRICS

Blockade of dopamine D3 receptors in frontal cortex, but not in sub-cortical structures, enhances social recognition in rats: Similar actions of D1 receptor agonists, but not of D2 antagonists

(2008) Florence Loiseau et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY