Progressive decline in tacrolimus clearance after renal transplantation is partially explained by decreasing CYP3A4 activity and increasing haematocrit

The CYP3A4*22 C>T single nucleotide polymorphism is associated with reduced midazolam and tacrolimus clearance in stable renal allograft recipients

(2014) H de Jonge et al.   PHARMACOGENOMICS JOURNAL

Impact of CYP3A5 genotype on tacrolimus versus midazolam clearance in renal transplant recipients: new insights in CYP3A5-mediated drug metabolism

(2013) Hylke de Jonge et al.   PHARMACOGENOMICS

In Vivo CYP3A4 Activity, CYP3A5 Genotype, and Hematocrit Predict Tacrolimus Dose Requirements and Clearance in Renal Transplant Patients

(2012) H de Jonge et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

A New Functional CYP3A4 Intron 6 Polymorphism Significantly Affects Tacrolimus Pharmacokinetics in Kidney Transplant Recipients

(2011) L. Elens et al.   CLINICAL CHEMISTRY

In Vivo CYP3A Activity Is Significantly Lower in Cyclosporine-Treated as Compared With Tacrolimus-Treated Renal Allograft Recipients

(2011) H de Jonge et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

A highly sensitive liquid chromatography tandem mass spectrometry method for simultaneous quantification of midazolam, 1′-hydroxymidazolam and 4-hydroxymidazolam in human plasma

(2010) Henriette de Loor et al.   BIOMEDICAL CHROMATOGRAPHY

Multi-center evaluation of a commercial Kit for tacrolimus determination by LC/MS/MS

(2010) Kimberly L. Napoli et al.   CLINICAL BIOCHEMISTRY

The Drug Transporter−Metabolism Alliance: Uncovering and Defining the Interplay

(2009) Leslie Z. Benet   MOLECULAR PHARMACEUTICS

New Insights Into the Pharmacokinetics and Pharmacodynamics of the Calcineurin Inhibitors and Mycophenolic Acid: Possible Consequences for Therapeutic Drug Monitoring in Solid Organ Transplantation

(2009) Hylke de Jonge et al.   THERAPEUTIC DRUG MONITORING

CYP3A5 genotype is not associated with a higher risk of acute rejection in tacrolimus-treated renal transplant recipients

(2008) Dennis A. Hesselink et al.   Pharmacogenetics and Genomics

Maturation of Dose-Corrected Tacrolimus Predose Trough Levels in Pediatric Kidney Allograft Recipients

(2008) Maarten Naesens et al.   TRANSPLANTATION