The cancer angiogenesis co-culture assay: In vitro quantification of the angiogenic potential of tumoroids

Consensus guidelines for the use and interpretation of angiogenesis assays

(2018) Patrycja Nowak-Sliwinska et al.   ANGIOGENESIS

A Living Biobank of Breast Cancer Organoids Captures Disease Heterogeneity

(2018) Norman Sachs et al.   CELL

Overall survival in MERiDiAN, a double-blind placebo-controlled randomised phase III trial evaluating first-line bevacizumab plus paclitaxel for HER2-negative metastatic breast cancer

(2018) David Miles et al.   EUROPEAN JOURNAL OF CANCER

Molecular Pharmacology of VEGF-A Isoforms: Binding and Signalling at VEGFR2

(2018) Chloe Peach et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Patient-derived organoids model treatment response of metastatic gastrointestinal cancers

(2018) Georgios Vlachogiannis et al.   SCIENCE

Colorectal cancer liver metastases organoids retain characteristics of original tumor and acquire chemotherapy resistance

(2018) Jon N. Buzzelli et al.   Stem Cell Research

Short-term spheroid culture of primary colorectal cancer cells as an in vitro model for personalizing cancer medicine

(2017) Maria Jeppesen et al.   PLoS One

Studying the influence of angiogenesis in in vitro cancer model systems

(2016) Laila C. Roudsari et al.   ADVANCED DRUG DELIVERY REVIEWS

ESMO consensus guidelines for the management of patients with metastatic colorectal cancer

(2016) E. Van Cutsem et al.   ANNALS OF ONCOLOGY

Vessel co-option mediates resistance to anti-angiogenic therapy in liver metastases

(2016) Sophia Frentzas et al.   NATURE MEDICINE

Ten years of anti-vascular endothelial growth factor therapy

(2016) Napoleone Ferrara et al.   NATURE REVIEWS DRUG DISCOVERY

Dynamic Contrast-Enhanced Magnetic Resonance Imaging as a Surrogate Biomarker for Bevacizumab in Colorectal Cancer Liver Metastasis: A Single-Arm, Exploratory Trial

(2016) Yeo-Eun Kim et al.   Cancer Research and Treatment

Multi-parametric hydrogels support 3D in vitro bioengineered microenvironment models of tumour angiogenesis

(2015) Laura J. Bray et al.   BIOMATERIALS

Prospective Derivation of a Living Organoid Biobank of Colorectal Cancer Patients

(2015) Marc van de Wetering et al.   CELL

Regorafenib plus best supportive care versus placebo plus best supportive care in Asian patients with previously treated metastatic colorectal cancer (CONCUR): a randomised, double-blind, placebo-controlled, phase 3 trial

(2015) Jin Li et al.   LANCET ONCOLOGY

Genetic variability of VEGF pathway genes in six randomized phase III trials assessing the addition of bevacizumab to standard therapy

(2014) Sanne de Haas et al.   ANGIOGENESIS

Cancer incidence and mortality worldwide: Sources, methods and major patterns in GLOBOCAN 2012

(2014) Jacques Ferlay et al.   INTERNATIONAL JOURNAL OF CANCER

Antiangiogenesis therapy: an update after the first decade

(2014) Sandro De Falco   KOREAN JOURNAL OF INTERNAL MEDICINE

Proangiogenic tumor proteins as potential predictive or prognostic biomarkers for bevacizumab therapy in metastatic colorectal cancer

(2013) Maressa A. Bruhn et al.   INTERNATIONAL JOURNAL OF CANCER

Efficacy and Safety of Bevacizumab in Metastatic Colorectal Cancer: Pooled Analysis From Seven Randomized Controlled Trials

(2013) H. I. Hurwitz et al.   ONCOLOGIST

Vascular Normalization as a Therapeutic Strategy for Malignant and Nonmalignant Disease

(2013) S. Goel et al.   Cold Spring Harbor Perspectives in Medicine

Vessel co-option in primary human tumors and metastases: an obstacle to effective anti-angiogenic treatment?

(2013) Tom Donnem et al.   Cancer Medicine

Predictive Impact of Circulating Vascular Endothelial Growth Factor in Four Phase III Trials Evaluating Bevacizumab

(2012) P. S. Hegde et al.   CLINICAL CANCER RESEARCH

Regorafenib monotherapy for previously treated metastatic colorectal cancer (CORRECT): an international, multicentre, randomised, placebo-controlled, phase 3 trial

(2012) Axel Grothey et al.   LANCET

Uses of thein vitroendothelial–fibroblast organotypic co-culture assay in angiogenesis research : Figure 1

(2011) Clare Hetheridge et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Intra-Laboratory Pre-Validation of a Human Cell Based in vitro Angiogenesis Assay for Testing Angiogenesis Modulators

(2011) Jertta-Riina Sarkanen et al.   Frontiers in Pharmacology

Regorafenib (BAY 73-4506): A new oral multikinase inhibitor of angiogenic, stromal and oncogenic receptor tyrosine kinases with potent preclinical antitumor activity

(2010) Scott M. Wilhelm et al.   INTERNATIONAL JOURNAL OF CANCER

Association of plasma VEGF-A, soluble VEGFR-1 and VEGFR-2 levels and clinical response and survival in advanced colorectal cancer patients receiving bevacizumab with modified FOLFOX6

(2010) YOSHIKO AOYAGI et al.   Oncology Letters

Distinct Patterns of Cytokine and Angiogenic Factor Modulation and Markers of Benefit for Vandetanib and/or Chemotherapy in Patients With Non–Small-Cell Lung Cancer

(2009) Emer O. Hanrahan et al.   JOURNAL OF CLINICAL ONCOLOGY

A Novel Assay to Assess the Effectiveness of Antiangiogenic Drugs in Human Breast Cancer

(2008) John M. Lyons et al.   ANNALS OF SURGICAL ONCOLOGY