Vitamin D3 attenuates doxorubicin-induced senescence of human aortic endothelial cells by upregulation of IL-10 via the pAMPKα/Sirt1/Foxo3a signaling pathway

Follicular regulatory T cells infiltrated the ovarian carcinoma and resulted in CD8 T cell dysfunction dependent on IL-10 pathway

(2019) Li Li et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Effect of High-Dose vs Standard-Dose Vitamin D3 Supplementation on Progression-Free Survival Among Patients With Advanced or Metastatic Colorectal Cancer

(2019) Kimmie Ng et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Vitamin D receptor activation regulates microglia polarization and oxidative stress in spontaneously hypertensive rats and angiotensin II-exposed microglial cells: Role of renin-angiotensin system

(2019) Changmeng Cui et al.   Redox Biology

Vitamin D and regulation of vascular cell function

(2018) Nasim Jamali et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Vitamin D: Classic and Novel Actions

(2018) Ángel Gil et al.   ANNALS OF NUTRITION AND METABOLISM

Doxorubicin targets multiple players: A new view of an old problem

(2018) Donato Cappetta et al.   PHARMACOLOGICAL RESEARCH

Hallmarks of Cellular Senescence

(2018) Alejandra Hernandez-Segura et al.   TRENDS IN CELL BIOLOGY

The Biological Activities of Vitamin D and Its Receptor in Relation to Calcium and Bone Homeostasis, Cancer, Immune and Cardiovascular Systems, Skin Biology, and Oral Health

(2018) R. A. G. Khammissa et al.   Biomed Research International

DOX-Vit D, a Novel Doxorubicin Delivery Approach, Inhibits Human Osteosarcoma Cell Proliferation by Inducing Apoptosis While Inhibiting Akt and mTOR Signaling Pathways

(2018) Zaid Maayah et al.   Pharmaceutics

ROS signaling under metabolic stress: cross-talk between AMPK and AKT pathway

(2017) Yang Zhao et al.   Molecular Cancer

Phosphorylation and acetylation modifications of FOXO3a: Independently or synergistically?

(2017) Xianwang Wang et al.   Oncology Letters

Vitamin D deficiency and supplementation in patients with aggressive B-cell lymphomas treated with immunochemotherapy

(2017) Stefan Hohaus et al.   Cancer Medicine

Vitamin D Receptor Activation Reduces Angiotensin-II–Induced Dissecting Abdominal Aortic Aneurysm in Apolipoprotein E–Knockout MiceHighlights

(2016) Sara Martorell et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Effects of Vitamin D on Cardiac Function in Patients With Chronic HF

(2016) Klaus K. Witte et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Vascular ageing and endothelial cell senescence: Molecular mechanisms of physiology and diseases

(2016) Carla Regina et al.   MECHANISMS OF AGEING AND DEVELOPMENT

NLRP3 Deficiency Reduces Macrophage Interleukin-10 Production and Enhances the Susceptibility to Doxorubicin-induced Cardiotoxicity

(2016) Motoi Kobayashi et al.   Scientific Reports

AMPK-Dependent Phosphorylation of GAPDH Triggers Sirt1 Activation and Is Necessary for Autophagy upon Glucose Starvation

(2015) Chunmei Chang et al.   MOLECULAR CELL

Vitamin D protects endothelial cells from irradiation-induced senescence and apoptosis by modulating MAPK/SirT1 axis

(2015) F. Marampon et al.   JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION

Cardiotoxicity of doxorubicin is mediated through mitochondrial iron accumulation

(2014) Yoshihiko Ichikawa et al.   JOURNAL OF CLINICAL INVESTIGATION

SIRT1 Is Required for AMPK Activation and the Beneficial Effects of Resveratrol on Mitochondrial Function

(2012) Nathan L. Price et al.   Cell Metabolism

Altered immunoregulatory profile during anti-tumour necrosis factor treatment of patients with inflammatory bowel disease

(2012) J. Grundström et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Endothelial vascular toxicity from chemotherapeutic agents: Preclinical evidence and clinical implications

(2011) Aspasia Soultati et al.   CANCER TREATMENT REVIEWS

Understanding the molecular mechanisms of the multifaceted IL-10-mediated anti-inflammatory response: Lessons from neutrophils

(2010) Flavia Bazzoni et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

The genes encoding cytokines IL-2, IL-10 and IL-12B are primary 1α,25(OH)2D3 target genes

(2010) Juha M. Matilainen et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Doxorubicin Cardiomyopathy

(2009) Kanu Chatterjee et al.   CARDIOLOGY

1α,25-Dihydroxyvitamin D3Reduces c-Myc Expression, Inhibiting Proliferation and Causing G1Accumulation in C4-2 Prostate Cancer Cells

(2009) JoyAnn N. Phillips Rohan et al.   ENDOCRINOLOGY

Functional Vitamin D Receptor (VDR) in the T-Tubules of Cardiac Myocytes: VDR Knockout Cardiomyocyte Contractility

(2007) Daniel X. Tishkoff et al.   ENDOCRINOLOGY