Therapeutic targets of natural products for the management of cardiovascular symptoms of coronavirus disease 2019

Angiotensin-converting enzyme 2 (ACE2) as a SARS-CoV-2 receptor: molecular mechanisms and potential therapeutic target

(2020) Haibo Zhang et al.   INTENSIVE CARE MEDICINE

A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-to-person transmission: a study of a family cluster

(2020) Jasper Fuk-Woo Chan et al.   LANCET

Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China

(2020) Chaolin Huang et al.   LANCET

A new coronavirus associated with human respiratory disease in China

(2020) Fan Wu et al.   NATURE

Pathological findings of COVID-19 associated with acute respiratory distress syndrome

(2020) Zhe Xu et al.   Lancet Respiratory Medicine

SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor

(2020) Markus Hoffmann et al.   CELL

Chinese yam extract and adenosine attenuated LPS-induced cardiac dysfunction by inhibiting RAS and apoptosis via the ER-mediated activation of SHC/Ras/Raf1 pathway

(2019) Mengnan Zeng et al.   PHYTOMEDICINE

Mechanism of Inhibition of Ebola Virus RNA-Dependent RNA Polymerase by Remdesivir

(2019) Egor Tchesnokov et al.   Viruses-Basel

Isolation and Characterization of Angiotensin Converting Enzyme Inhibitory Peptides from Peach Seed Hydrolysates: In Vivo Assessment of Antihypertensive Activity

(2019) Romy Vásquez-Villanueva et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Carthamus tinctorius L. extract improves hemodynamic and vascular alterations in a rat model of renovascular hypertension through Ang II-AT 1 R-NADPH oxidase pathway

(2018) Sarawoot Bunbupha et al.   ANNALS OF ANATOMY-ANATOMISCHER ANZEIGER

Optimized Camellia sinensis var . sinensis , Ilex paraguariensis , and Aspalathus linearis blend presents high antioxidant and antiproliferative activities in a beverage model

(2018) Jânio S. Santos et al.   FOOD CHEMISTRY

Coronavirus Susceptibility to the Antiviral Remdesivir (GS-5734) Is Mediated by the Viral Polymerase and the Proofreading Exoribonuclease

(2018) Maria L. Agostini et al.   mBio

Qiliqiangxin Protects against Renal Injury in Rat with Cardiorenal Syndrome Type I through Regulating the Inflammatory and Oxidative Stress Signaling

(2018) Xiaoyu Duan et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Characterization and Antioxidant and Angiotensin I-Converting Enzyme (ACE)-Inhibitory Activities of Gelatin Hydrolysates Prepared from Extrusion-Pretreated Milkfish (Chanos chanos) Scale

(2018) Chun-Yung Huang et al.   Marine Drugs

Macrocyclic lactones from seafood Amphioctopus neglectus: Newly described natural leads to attenuate angiotensin-II induced cardiac hypertrophy

(2018) Kajal Chakraborty et al.   BIOMEDICINE & PHARMACOTHERAPY

Ginsenoside Rb1 improves cardiac function and remodeling in heart failure

(2017) Xian Zheng et al.   EXPERIMENTAL ANIMALS

Angiotensin I-converting enzyme (ACE) inhibitory activity of Fucus spiralis macroalgae and influence of the extracts storage temperature—A short report

(2016) Lisete Paiva et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Nicotianamine is a novel angiotensin-converting enzyme 2 inhibitor in soybean

(2015) Saori TAKAHASHI et al.   BIOMEDICAL RESEARCH-TOKYO

Traditional Chinese Medication Qiliqiangxin attenuates cardiac remodeling after acute myocardial infarction in mice

(2015) Lichan Tao et al.   Scientific Reports

Simulated digestion of proanthocyanidins in grape skin and seed extracts and the effects of digestion on the angiotensin I-converting enzyme (ACE) inhibitory activity

(2013) Katherina Fernández et al.   FOOD CHEMISTRY

Angiotensin Converting Enzyme (ACE) Inhibition Activity of Standardized Extract of the Ocimum sanctum L. Leaves and its Fractions

(2013) SK Chaudhary et al.   PLANTA MEDICA

l-Theanine promotes nitric oxide production in endothelial cells through eNOS phosphorylation

(2012) Jamila H. Siamwala et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Qiliqiangxin Improves Cardiac Function in Spontaneously Hypertensive Rats Through the Inhibition of Cardiac Chymase

(2011) W. Liu et al.   AMERICAN JOURNAL OF HYPERTENSION

Characterization of a highly polymeric proanthocyanidin fraction from persimmon pulp with strong Chinese cobra PLA2 inhibition effects

(2011) Shu-fen Xu et al.   FITOTERAPIA

Antioxidant activities, sensory and anti-influenza activity of grape skin tea infusion

(2011) Alaa El-Din A. Bekhit et al.   FOOD CHEMISTRY

Anti-obesity effects of highly polymeric proanthocyanidins from seed shells of Japanese horse chestnut (Aesculus turbinata Blume)

(2010) Hideto Kimura et al.   FOOD RESEARCH INTERNATIONAL

Angiotensin-I-Converting Enzyme (ACE) Inhibitors from Marine Resources: Prospects in the Pharmaceutical Industry

(2010) Isuru Wijesekara et al.   Marine Drugs

Cardiovascular friendly natural products: a promising approach in the management of CVD

(2010) Santosh K. Shukla et al.   NATURAL PRODUCT RESEARCH

Effects of green tea, black tea and Rooibos tea on angiotensin-converting enzyme and nitric oxide in healthy volunteers

(2010) Ingrid A-L Persson et al.   PUBLIC HEALTH NUTRITION

Qiliqiangxin regulates the balance between tumor necrosis factor-α and interleukin-10 and improves cardiac function in rats with myocardial infarction

(2009) Hong Xiao et al.   CELLULAR IMMUNOLOGY

The angiotensin-(1–7) receptor agonist AVE0991 is cardioprotective in diabetic rats

(2008) Linda Ebermann et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

The discovery of angiotensin-converting enzyme 2 and its role in acute lung injury in mice

(2008) Yumiko Imai et al.   EXPERIMENTAL PHYSIOLOGY

Total Polyphenol Content and Antioxidant Capacity of Commercially Available Tea (Camellia sinensis) in Argentina

(2008) Claudia Anesini et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Angiotensin-converting enzyme 2 (ACE2) expression and activity in human carotid atherosclerotic lesions

(2008) JC Sluimer et al.   JOURNAL OF PATHOLOGY