Opioid receptor system contributes to the acute and sustained antidepressant-like effects, but not the hyperactivity motor effects of ketamine in mice

The Roles of Endogenous Opioid System in the Antidepressant Actions of Ketamine

(2021) Cheng Jiang et al.   BIOLOGICAL PSYCHIATRY

Naltrexone is neuroprotective against traumatic brain injury in mu opioid receptor knockout mice

(2021) Yu‐Syuan Wang et al.   CNS Neuroscience & Therapeutics

Opioid system is necessary but not sufficient for antidepressive actions of ketamine in rodents

(2020) Matthew E. Klein et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Association of Combined Naltrexone and Ketamine With Depressive Symptoms in a Case series of Patients With Depression and Alcohol Use Disorder

(2019) Gihyun Yoon et al.   JAMA Psychiatry

(2R,6R)-hydroxynorketamine exerts mGlu2receptor-dependent antidepressant actions

(2019) Panos Zanos et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ketamine: A Paradigm Shift for Depression Research and Treatment

(2019) John H. Krystal et al.   NEURON

( R )‐Ketamine exerts antidepressant actions partly via conversion to ( 2R,6R )‐hydroxynorketamine, while causing adverse effects at sub‐anaesthetic doses

(2019) Panos Zanos et al.   BRITISH JOURNAL OF PHARMACOLOGY

Targeting opioid dysregulation in depression for the development of novel therapeutics

(2019) Caroline A. Browne et al.   PHARMACOLOGY & THERAPEUTICS

Comparison of antidepressant and side effects in mice after intranasal administration of (R,S)-ketamine, (R)-ketamine, and (S)-ketamine

(2019) Lijia Chang et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Stress-sensitive antidepressant-like effects of ketamine in the mouse forced swim test

(2019) Paul J. Fitzgerald et al.   PLoS One

Attenuation of antidepressant and antisuicidal effects of ketamine by opioid receptor antagonism

(2019) Nolan R. Williams et al.   MOLECULAR PSYCHIATRY

Ketamine and Ketamine Metabolite Pharmacology: Insights into Therapeutic Mechanisms

(2018) Panos Zanos et al.   PHARMACOLOGICAL REVIEWS

Attenuation of Antidepressant Effects of Ketamine by Opioid Receptor Antagonism

(2018) Nolan R. Williams et al.   AMERICAN JOURNAL OF PSYCHIATRY

Lack of Opioid System in the Antidepressant Actions of Ketamine

(2018) Kai Zhang et al.   BIOLOGICAL PSYCHIATRY

Activity-dependent brain-derived neurotrophic factor signaling is required for the antidepressant actions of (2R,6R)-hydroxynorketamine

(2018) Kenichi Fukumoto et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Antidepressant Potential of ( R )-Ketamine in Rodent Models: Comparison with ( S )-Ketamine

(2017) Kenichi Fukumoto et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Ketamine for Social Anxiety Disorder: A Randomized, Placebo-Controlled Crossover Trial

(2017) Jerome H Taylor et al.   NEUROPSYCHOPHARMACOLOGY

Kappa-Opioid Antagonists for Psychiatric Disorders: From Bench to Clinical Trials

(2016) William A. Carlezon et al.   DEPRESSION AND ANXIETY

NMDAR inhibition-independent antidepressant actions of ketamine metabolites

(2016) Panos Zanos et al.   NATURE

A brief history of the development of antidepressant drugs: From monoamines to glutamate.

(2015) Todd M. Hillhouse et al.   EXPERIMENTAL AND CLINICAL PSYCHOPHARMACOLOGY

Ketamine and other N-methyl-D-aspartate receptor antagonists in the treatment of depression: a perspective review

(2015) Nicolas D. Iadarola et al.   Therapeutic Advances in Chronic Disease

Central antinociception induced by ketamine is mediated by endogenous opioids and μ- and δ-opioid receptors

(2014) Daniela da Fonseca Pacheco et al.   BRAIN RESEARCH

The Role of Ketamine in Treatment-Resistant Depression: A Systematic Review

(2014) Gianluca Serafini et al.   Current Neuropharmacology

EFFECTS OF KETAMINE ON EXPLICIT AND IMPLICIT SUICIDAL COGNITION: A RANDOMIZED CONTROLLED TRIAL IN TREATMENT-RESISTANT DEPRESSION

(2014) Rebecca B. Price et al.   DEPRESSION AND ANXIETY

Ketamine, but not MK-801, produces antidepressant-like effects in rats responding on a differential-reinforcement-of-low-rate operant schedule

(2013) Todd M. Hillhouse et al.   BEHAVIOURAL PHARMACOLOGY

MAJOR DEPRESSIVE DISORDER IN DSM-5: IMPLICATIONS FOR CLINICAL PRACTICE AND RESEARCH OF CHANGES FROM DSM-IV

(2013) Rudolf Uher et al.   DEPRESSION AND ANXIETY

Urgent Ketamine Infusion Rapidly Eliminated Suicidal Ideation for a Patient With Major Depressive Disorder

(2013) Daniel Zigman et al.   JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY

Tramadol Pretreatment Enhances Ketamine-Induced Antidepressant Effects and Increases Mammalian Target of Rapamycin in Rat Hippocampus and Prefrontal Cortex

(2012) Chun Yang et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Potentiation of μ-opioid receptor-mediated signaling by ketamine

(2011) Achla Gupta et al.   JOURNAL OF NEUROCHEMISTRY

NMDA receptor blockade at rest triggers rapid behavioural antidepressant responses

(2011) Anita E. Autry et al.   NATURE

The antidepressant-like effects of glutamatergic drugs ketamine and AMPA receptor potentiator LY 451646 are preserved in bdnf+/− heterozygous null mice

(2011) Jesse S.O. Lindholm et al.   NEUROPHARMACOLOGY

Effect of ketamine on exploratory behaviour in BALB/C and C57BL/6 mice

(2011) Kubra Akillioglu et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Taming the Ketamine Tiger

(2010) Edward F. Domino   ANESTHESIOLOGY

A Randomized Add-on Trial of an N-methyl-D-aspartate Antagonist in Treatment-Resistant Bipolar Depression

(2010) Nancy Diazgranados et al.   ARCHIVES OF GENERAL PSYCHIATRY

Comparison of the opioid receptor antagonist properties of naltrexone and 6β-naltrexol in morphine-naïve and morphine-dependent mice

(2008) Mary F. Divin et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Cellular Mechanisms Underlying the Antidepressant Effects of Ketamine: Role of α-Amino-3-Hydroxy-5-Methylisoxazole-4-Propionic Acid Receptors

(2007) Sungho Maeng et al.   BIOLOGICAL PSYCHIATRY