Resveratrol Alleviates 27-Hydroxycholesterol-Induced Senescence in Nerve Cells and Affects Zebrafish Locomotor Behavior via Activation of SIRT1-Mediated STAT3 Signaling

Activation of STAT-3 signalling by RECK downregulation via ROS is involved in the 27-hydroxycholesterol-induced invasion in breast cancer cells

(2020) Zhaoxia Shen et al.   FREE RADICAL RESEARCH

Nicotinic Acetylcholine Receptors of PC12 Cells

(2020) Kamilla Mussina et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Obesity and Cancer: 27-Hydroxycholesterol, the Missing Link

(2020) Arvand Asghari et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Sex‐difference in flux of 27‐hydroxycholesterol in the brain

(2020) Cristina Parrado‐Fernandez et al.   BRITISH JOURNAL OF PHARMACOLOGY

Cx43 Inhibition Attenuates Sepsis-Induced Intestinal Injury via Downregulating ROS Transfer and the Activation of the JNK1/Sirt1/FoxO3a Signaling Pathway

(2019) Zhaowei Zou et al.   MEDIATORS OF INFLAMMATION

Resveratrol reduces senescence-associated secretory phenotype by SIRT1/NF-κB pathway in gut of the annual fish Nothobranchius guentheri

(2018) Shan Liu et al.   FISH & SHELLFISH IMMUNOLOGY

STAT3: a multifaceted oncoprotein

(2018) Aleks C. Guanizo et al.   GROWTH FACTORS

STAT3 and apoptosis challenges in cancer

(2018) Nazanin Fathi et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

SLAB51 Probiotic Formulation Activates SIRT1 Pathway Promoting Antioxidant and Neuroprotective Effects in an AD Mouse Model

(2018) Laura Bonfili et al.   MOLECULAR NEUROBIOLOGY

Targeting the IL-6/JAK/STAT3 signalling axis in cancer

(2018) Daniel E. Johnson et al.   Nature Reviews Clinical Oncology

Neuroprotective Mechanisms of Resveratrol in Alzheimer’s Disease: Role of SIRT1

(2018) Bruno Alexandre Quadros Gomes et al.   Oxidative Medicine and Cellular Longevity

27-Hydroxycholesterol induces invasion and migration of breast cancer cells by increasing MMP9 and generating EMT through activation of STAT-3

(2017) Zhaoxia Shen et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

A High-Cholesterol Diet Increases 27-Hydroxycholesterol and Modifies Estrogen Receptor Expression and Neurodegeneration in Rabbit Hippocampus

(2017) Sylwia W. Brooks et al.   JOURNAL OF ALZHEIMERS DISEASE

Resveratrol regulates neuro-inflammation and induces adaptive immunity in Alzheimer’s disease

(2017) Charbel Moussa et al.   Journal of Neuroinflammation

The ROS-mediated activation of IL-6/STAT3 signaling pathway is involved in the 27-hydroxycholesterol-induced cellular senescence in nerve cells

(2017) Jiao Liu et al.   TOXICOLOGY IN VITRO

Discovery of oral-available resveratrol-caffeic acid based hybrids inhibiting acetylated and phosphorylated STAT3 protein

(2016) Shanshan Li et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

The ROS-mediated activation of STAT-3/VEGF signaling is involved in the 27-hydroxycholesterol-induced angiogenesis in human breast cancer cells

(2016) Dongmei Zhu et al.   TOXICOLOGY LETTERS

Resveratrol serves as a protein-substrate interaction stabilizer in human SIRT1 activation

(2016) Xuben Hou et al.   Scientific Reports

The suitability of BV2 cells as alternative model system for primary microglia cultures or for animal experiments examining brain inflammation

(2016) Anja Henn   ALTEX-Alternatives to Animal Experimentation

The zebrafish as a gerontology model in nervous system aging, disease, and repair

(2015) Jessie Van houcke et al.   AGEING RESEARCH REVIEWS

Does the oxysterol 27-hydroxycholesterol underlie Alzheimer's disease–Parkinson's disease overlap?

(2015) Gurdeep Marwarha et al.   EXPERIMENTAL GERONTOLOGY

Acetylation and phosphorylation of STAT3 are involved in the responsiveness of microglia to beta amyloid

(2015) Margherita Eufemi et al.   NEUROCHEMISTRY INTERNATIONAL

27-Hydroxycholesterol contributes to disruptive effects on learning and memory by modulating cholesterol metabolism in the rat brain

(2015) D.-D. Zhang et al.   NEUROSCIENCE

Automated Scalable Heat Shock Modification for Standard Aquatic Housing Systems

(2015) Alfonso Saera-Vila et al.   Zebrafish

P300-dependent STAT3 acetylation is necessary for angiotensin II-induced pro-fibrotic responses in renal tubular epithelial cells

(2014) Jun Ni et al.   ACTA PHARMACOLOGICA SINICA

Arsenic trioxide attenuates the invasion potential of human liver cancer cells through the demethylation-activated microRNA-491

(2014) Xingxing Wang et al.   TOXICOLOGY LETTERS

SRC Signaling Is Crucial in the Growth of Synovial Sarcoma Cells

(2013) S. Michels et al.   CANCER RESEARCH

Role of Resveratrol and its Analogues in the Treatment of Neurodegenerative Diseases: Focus on Recent Discoveries

(2012) V. Foti Cuzzola et al.   CNS & Neurological Disorders-Drug Targets

Sirtuins as regulators of metabolism and healthspan

(2012) Riekelt H. Houtkooper et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Effects of hallucinogenic agents mescaline and phencyclidine on zebrafish behavior and physiology

(2012) Evan J. Kyzar et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Oxidative Damage Targets Complexes Containing DNA Methyltransferases, SIRT1, and Polycomb Members to Promoter CpG Islands

(2011) Heather M. O'Hagan et al.   CANCER CELL

Characterization of behavioral and endocrine effects of LSD on zebrafish

(2010) Leah Grossman et al.   BEHAVIOURAL BRAIN RESEARCH

STAT3-dependent effects of IL-22 in human keratinocytes are counterregulated by sirtuin 1 through a direct inhibition of STAT3 acetylation

(2010) Rosanna Sestito et al.   FASEB JOURNAL

Recent progress in the biology and physiology of sirtuins

(2009) Toren Finkel et al.   NATURE

miR-34a repression of SIRT1 regulates apoptosis

(2008) M. Yamakuchi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

27-Hydroxycholesterol Is an Endogenous Selective Estrogen Receptor Modulator

(2007) Carolyn D. DuSell et al.   MOLECULAR ENDOCRINOLOGY