Fungal biofilm composition and opportunities in drug discovery

Deacetylation of Fungal Exopolysaccharide Mediates Adhesion and Biofilm Formation

(2016) Mark J. Lee et al.   mBio

Characterization of the Vibrio cholerae extracellular matrix: A top-down solid-state NMR approach

(2015) Courtney Reichhardt et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Spectral Snapshots of Bacterial Cell-Wall Composition and the Influence of Antibiotics by Whole-Cell NMR

(2015) Rie Nygaard et al.   BIOPHYSICAL JOURNAL

Analysis of the Aspergillus fumigatus Biofilm Extracellular Matrix by Solid-State Nuclear Magnetic Resonance Spectroscopy

(2015) Courtney Reichhardt et al.   EUKARYOTIC CELL

Bottom-up and top-down solid-state NMR approaches for bacterial biofilm matrix composition

(2015) Lynette Cegelski   JOURNAL OF MAGNETIC RESONANCE

Nanoscale biophysical properties of the cell surface galactosaminogalactan from the fungal pathogen Aspergillus fumigatus

(2015) Audrey Beaussart et al.   Nanoscale

Cellulose-Pectin Spatial Contacts Are Inherent to Never-Dried Arabidopsis Primary Cell Walls: Evidence from Solid-State Nuclear Magnetic Resonance

(2015) Tuo Wang et al.   PLANT PHYSIOLOGY

Pel is a cationic exopolysaccharide that cross-links extracellular DNA in thePseudomonas aeruginosabiofilm matrix

(2015) Laura K. Jennings et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Community participation in biofilm matrix assembly and function

(2015) Kaitlin F. Mitchell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Synergistic combinations of antifungals and anti-virulence agents to fight againstCandida albicans

(2015) Jinhui Cui et al.   Virulence

The Fungal Exopolysaccharide Galactosaminogalactan Mediates Virulence by Enhancing Resistance to Neutrophil Extracellular Traps

(2015) Mark J. Lee et al.   PLoS Pathogens

Development and antimicrobial susceptibility studies of in vitro monomicrobial and polymicrobial biofilm models with Aspergillus fumigatus and Pseudomonas aeruginosa

(2014) Elias K Manavathu et al.   BMC MICROBIOLOGY

Stress responses go three dimensional - the spatial order of physiological differentiation in bacterial macrocolony biofilms

(2014) Diego O. Serra et al.   ENVIRONMENTAL MICROBIOLOGY

Aspergillus Cell Wall and Biofilm

(2014) Anne Beauvais et al.   MYCOPATHOLOGIA

Amphotericin forms an extramembranous and fungicidal sterol sponge

(2014) Thomas M Anderson et al.   Nature Chemical Biology

Structural Characterization of the Extracellular Polysaccharide from Vibrio cholerae O1 El-Tor

(2014) Fitnat Yildiz et al.   PLoS One

Novel Entries in a Fungal Biofilm Matrix Encyclopedia

(2014) R. Zarnowski et al.   mBio

Efficacy of reducing sugar and phenol–sulfuric acid assays for analysis of soluble carbohydrates in feedstuffs

(2013) Mary Beth Hall   ANIMAL FEED SCIENCE AND TECHNOLOGY

Recent insights into Candida albicans biofilm resistance mechanisms

(2013) Lotte Mathé et al.   CURRENT GENETICS

Extracellular DNA Release Acts as an Antifungal Resistance Mechanism in Mature Aspergillus fumigatus Biofilms

(2013) Ranjith Rajendran et al.   EUKARYOTIC CELL

Mechanisms ofCandidabiofilm drug resistance

(2013) Heather T Taff et al.   Future Microbiology

Biofilm infections, their resilience to therapy and innovative treatment strategies

(2013) U. Römling et al.   JOURNAL OF INTERNAL MEDICINE

Sum of the Parts: Composition and Architecture of the Bacterial Extracellular Matrix

(2013) Oscar A. McCrate et al.   JOURNAL OF MOLECULAR BIOLOGY

Solid-state NMR for bacterial biofilms

(2013) Courtney Reichhardt et al.   MOLECULAR PHYSICS

The in vivo biofilm

(2013) Thomas Bjarnsholt et al.   TRENDS IN MICROBIOLOGY

Microanatomy at Cellular Resolution and Spatial Order of Physiological Differentiation in a Bacterial Biofilm

(2013) D. O. Serra et al.   mBio

Candida albicanspathogenicity mechanisms

(2013) François L. Mayer et al.   Virulence

Aspergillus Galactosaminogalactan Mediates Adherence to Host Constituents and Conceals Hyphal β-Glucan from the Immune System

(2013) Fabrice N. Gravelat et al.   PLoS Pathogens

A sticky situation: extracellular DNA shapes Aspergillus fumigatus biofilms

(2013) Sven Krappmann et al.   Frontiers in Microbiology

Extrinsic extracellular DNA leads to biofilm formation and colocalizes with matrix polysaccharides in the human pathogenic fungus Aspergillus fumigatus

(2013) Iordana Shopova et al.   Frontiers in Microbiology

In VitroInteraction between Alginate Lyase and Amphotericin B against Aspergillus fumigatus Biofilm Determined by Different Methods

(2012) Francesca Bugli et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Pectin–Cellulose Interactions in the Arabidopsis Primary Cell Wall from Two-Dimensional Magic-Angle-Spinning Solid-State Nuclear Magnetic Resonance

(2012) Tuo Wang et al.   BIOCHEMISTRY

Nutrient-Dependent Structural Changes in S. aureus Peptidoglycan Revealed by Solid-State NMR Spectroscopy

(2012) Xiaoxue Zhou et al.   BIOCHEMISTRY

The Nonsteroidal Antiinflammatory Drug Diclofenac Potentiates the In Vivo Activity of Caspofungin Against Candida albicans Biofilms

(2012) Anna Bink et al.   JOURNAL OF INFECTIOUS DISEASES

Multidimensional solid-state NMR studies of the structure and dynamics of pectic polysaccharides in uniformly 13C-labeled Arabidopsis primary cell walls

(2012) Marilu Dick-Perez et al.   MAGNETIC RESONANCE IN CHEMISTRY

Molecular Architecture and Assembly Principles of Vibrio cholerae Biofilms

(2012) V. Berk et al.   SCIENCE

Fungal Biofilms

(2012) Saranna Fanning et al.   PLoS Pathogens

A Candida Biofilm-Induced Pathway for Matrix Glucan Delivery: Implications for Drug Resistance

(2012) Heather T. Taff et al.   PLoS Pathogens

Azole Resistance of Aspergillus fumigatus Biofilms Is Partly Associated with Efflux Pump Activity

(2011) Ranjith Rajendran et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Structure and Interactions of Plant Cell-Wall Polysaccharides by Two- and Three-Dimensional Magic-Angle-Spinning Solid-State NMR

(2011) Marilú Dick-Pérez et al.   BIOCHEMISTRY

Interface of Candida albicans Biofilm Matrix-Associated Drug Resistance and Cell Wall Integrity Regulation

(2011) Jeniel E. Nett et al.   EUKARYOTIC CELL

Aspergillus fumigatusbiofilms in the clinical setting

(2011) Frank-Michael C. Müller et al.   MEDICAL MYCOLOGY

Addition of DNase improves the in vitro activity of antifungal drugs against Candida albicans biofilms

(2011) Margarida Martins et al.   MYCOSES

The Pel Polysaccharide Can Serve a Structural and Protective Role in the Biofilm Matrix of Pseudomonas aeruginosa

(2011) Kelly M. Colvin et al.   PLoS Pathogens

Interaction of Candida albicans Biofilms with Antifungals: Transcriptional Response and Binding of Antifungals to Beta-Glucans

(2010) G. Vediyappan et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

High-level antibiotic resistance in Pseudomonas aeruginosa biofilm: the ndvB gene is involved in the production of highly glycerol-phosphorylated  -(1->3)-glucans, which bind aminoglycosides

(2010) I. Sadovskaya et al.   GLYCOBIOLOGY

Antibiotic resistance of bacterial biofilms

(2010) Niels Høiby et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Genetic Basis ofCandidaBiofilm Resistance Due to Drug‐Sequestering Matrix Glucan

(2010) Jeniel E. Nett et al.   JOURNAL OF INFECTIOUS DISEASES

Demonstration of Antibiofilm and Antifungal Efficacy of Chitosan against Candidal Biofilms, Using an In Vivo Central Venous Catheter Model

(2010) Luis R. Martinez et al.   JOURNAL OF INFECTIOUS DISEASES

Functional genomic profiling of Aspergillus fumigatus biofilm reveals enhanced production of the mycotoxin gliotoxin

(2010) Sandra Bruns et al.   PROTEOMICS

In vivobiofilm composition ofAspergillus fumigatus

(2009) Céline Loussert et al.   CELLULAR MICROBIOLOGY

Our Current Understanding of Fungal Biofilms

(2009) Gordon Ramage et al.   CRITICAL REVIEWS IN MICROBIOLOGY

Characterization of a biofilm-like extracellular matrix inFLO1-expressingSaccharomyces cerevisiaecells

(2009) Anne Beauvais et al.   FEMS YEAST RESEARCH

Metabolic control of antifungal drug resistance

(2009) Nicole Robbins et al.   FUNGAL GENETICS AND BIOLOGY

Biofilms of non-Candida albicans Candidaspecies: quantification, structure and matrix composition

(2009) Sónia Silva et al.   MEDICAL MYCOLOGY

Presence of Extracellular DNA in the Candida albicans Biofilm Matrix and its Contribution to Biofilms

(2009) Margarida Martins et al.   MYCOPATHOLOGIA

Small-molecule inhibitors target Escherichia coli amyloid biogenesis and biofilm formation

(2009) Lynette Cegelski et al.   Nature Chemical Biology

Aspergillus fumigatus Forms Biofilms with Reduced Antifungal Drug Susceptibility on Bronchial Epithelial Cells

(2008) M. J. Seidler et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Phase-dependent antifungal activity against Aspergillus fumigatus developing multicellular filamentous biofilms

(2008) E. Mowat et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

The characteristics ofAspergillus fumigatusmycetoma development: is this a biofilm?

(2008) Eilidh Mowat et al.   MEDICAL MYCOLOGY

The biology and future prospects of antivirulence therapies

(2007) Lynette Cegelski et al.   NATURE REVIEWS MICROBIOLOGY