Androgen receptor regulates the proliferation of myoblasts under appropriate or excessive stretch through IGF-1 receptor mediated p38 and ERK1/2 pathways

Crucial role of androgen receptor in resistance and endurance trainings-induced muscle hypertrophy through IGF-1/IGF-1R- PI3K/Akt- mTOR pathway

(2020) Lijun YIN et al.   Nutrition & Metabolism

Low-Intensity Exercise Suppresses CCAAT/Enhancer-Binding Protein δ/Myostatin Pathway Through Androgen Receptor in Muscle Cells

(2019) Bo-Kyung Son et al.   GERONTOLOGY

Testosterone replacement therapy and cardiovascular risk

(2019) Thiago Gagliano-Jucá et al.   Nature Reviews Cardiology

Myonuclear accretion is a determinant of exercise-induced remodeling in skeletal muscle

(2019) Qingnian Goh et al.   eLife

Association of serum bone- and muscle-derived factors with age, sex, body composition, and physical function in community-dwelling middle-aged and elderly adults: a cross-sectional study

(2019) Kenta Moriwaki et al.   BMC MUSCULOSKELETAL DISORDERS

Effects of Cyclic Mechanical Stretch on the Proliferation of L6 Myoblasts and Its Mechanisms: PI3K/Akt and MAPK Signal Pathways Regulated by IGF-1 Receptor

(2018) Shaoting Fu et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Cross-talk between androgen and Wnt signaling potentially contributes to age-related skeletal muscle atrophy in rats

(2018) Petey W. Mumford et al.   JOURNAL OF APPLIED PHYSIOLOGY

Cleavage of caspase-12 at Asp94, mediated by endoplasmic reticulum stress (ERS), contributes to stretch-induced apoptosis of myoblasts

(2018) Jing Song et al.   JOURNAL OF CELLULAR PHYSIOLOGY

GSK2881078, a SARM, produces dose-dependent increases in lean mass in healthy older men and women

(2018) David Neil et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

miR-483 inhibits bovine myoblast cell proliferation and differentiation via IGF1/PI3K/AKT signal pathway

(2018) Chengchuang Song et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Muscle Androgen Receptor Content but Not Systemic Hormones Is Associated With Resistance Training-Induced Skeletal Muscle Hypertrophy in Healthy, Young Men

(2018) Robert W. Morton et al.   Frontiers in Physiology

Androgen receptor agonists increase lean mass, improve cardiopulmonary functions and extend survival in preclinical models of Duchenne muscular dystrophy

(2017) Suriyan Ponnusamy et al.   HUMAN MOLECULAR GENETICS

miR-18a induces myotubes atrophy by down-regulating IgfI

(2017) Chuncheng Liu et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Role of androgen receptor on cyclic mechanical stretch-regulated proliferation of C2C12 myoblasts and its upstream signals: IGF-1-mediated PI3K/Akt and MAPKs pathways

(2017) Yiming Ma et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Testosterone insulin-like effects: an in vitro study on the short-term metabolic effects of testosterone in human skeletal muscle cells

(2017) C. Antinozzi et al.   JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION

Treadmill Slope Modulates Inflammation, Fiber Type Composition, Androgen, and Glucocorticoid Receptors in the Skeletal Muscle of Overtrained Mice

(2017) Alisson L. da Rocha et al.   Frontiers in Immunology

Satellite cell depletion prevents fiber hypertrophy in skeletal muscle

(2016) Ingrid M. Egner et al.   DEVELOPMENT

Effects of Testosterone Supplementation for 3-Years on Muscle Performance and Physical Function in Older Men

(2016) Thomas W. Storer et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Testosterone therapy increases muscle mass in men with cirrhosis and low testosterone: A randomised controlled trial

(2016) Marie Sinclair et al.   JOURNAL OF HEPATOLOGY

Functional Overload Enhances Satellite Cell Properties in Skeletal Muscle

(2016) Shin Fujimaki et al.   Stem Cells International

Testosterone enables growth and hypertrophy in fusion impaired myoblasts that display myotube atrophy: deciphering the role of androgen and IGF-I receptors 

(2015) David C. Hughes et al.   BIOGERONTOLOGY

Insulin-like growth factor-1 (IGF-1) promotes myoblast proliferation and skeletal muscle growth of embryonic chickens via the PI3K/Akt signalling pathway

(2015) Minli Yu et al.   CELL BIOLOGY INTERNATIONAL

Expression of androgen receptor target genes in skeletal muscle

(2014) Kesha Rana et al.   ASIAN JOURNAL OF ANDROLOGY

Human androgen deficiency: insights gained from androgen receptor knockout mouse models

(2014) JeffreyD Zajac et al.   ASIAN JOURNAL OF ANDROLOGY

Myofiber Androgen Receptor Promotes Maximal Mechanical Overload-Induced Muscle Hypertrophy and Fiber Type Transition in Male Mice

(2014) Arnaud Ferry et al.   ENDOCRINOLOGY

A satellite cell-specific knockout of the androgen receptor reveals myostatin as a direct androgen target in skeletal muscle

(2014) Vanessa Dubois et al.   FASEB JOURNAL

Impaired hypertrophy in myoblasts is improved with testosterone administration

(2013) Colleen S. Deane et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Signaling pathways mediating the effects of insulin-like growth factor-I in bovine muscle satellite cells

(2013) Xiaomei Ge et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Ornithine decarboxylase is upregulated by the androgen receptor in skeletal muscle and regulates myoblast proliferation

(2011) Nicole K. L. Lee et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Novel evidence that testosterone promotes cell proliferation and differentiation via G protein-coupled receptors in the rat L6 skeletal muscle myoblast cell line

(2011) Rui Fu et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Testosterone-induced hypertrophy of L6 myoblasts is dependent upon Erk and mTOR

(2010) Yong Wu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The Role of GH and IGF-I in Mediating Anabolic Effects of Testosterone on Androgen-Responsive Muscle

(2010) Carlo Serra et al.   ENDOCRINOLOGY

Impaired muscle regeneration and myoblast differentiation in mice with a muscle-specific KO of IGF-IR

(2010) Lisa Heron-Milhavet et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Mouse model of testosterone-induced muscle fiber hypertrophy: involvement of p38 mitogen-activated protein kinase-mediated Notch signaling

(2009) Danielle Brown et al.   JOURNAL OF ENDOCRINOLOGY

Insulin-like growth factor-I-induced androgen receptor activation is mediated by the PI3K/Akt pathway in C2C12 skeletal muscle cells

(2009) Won Jun Lee   MOLECULES AND CELLS

Ligand-independent activation of the androgen receptor by insulin-like growth factor-i and the role of the MAPK pathway in skeletal muscle cells

(2009) Hye Jin Kim et al.   MOLECULES AND CELLS

Impaired skeletal muscle development and function in male, but not female, genomic androgen receptor knockout mice

(2008) Helen E. MacLean et al.   FASEB JOURNAL