LEO1 is a partner for Cockayne syndrome protein B (CSB) in response to transcription-blocking DNA damage

Current and emerging roles of Cockayne syndrome group B (CSB) protein

(2021) Vinod Tiwari et al.   NUCLEIC ACIDS RESEARCH

A CSB-PAF1C axis restores processive transcription elongation after DNA damage repair

(2021) Diana van den Heuvel et al.   Nature Communications

Defective transcription of ATF3 responsive genes, a marker for Cockayne Syndrome

(2020) Alexey Epanchintsev et al.   Scientific Reports

Ubiquitination of DNA Damage-Stalled RNAPII Promotes Transcription-Coupled Repair

(2020) Yuka Nakazawa et al.   CELL

Regulation of the RNAPII Pool Is Integral to the DNA Damage Response

(2020) Ana Tufegdžić Vidaković et al.   CELL

The cooperative action of CSB, CSA, and UVSSA target TFIIH to DNA damage-stalled RNA polymerase II

(2020) Yana van der Weegen et al.   Nature Communications

A C. elegans model for neurodegeneration in Cockayne syndrome

(2020) Amanda F C Lopes et al.   NUCLEIC ACIDS RESEARCH

Evidence that Moderate Eviction of Spt5 and Promotion of Error-Free Transcriptional Bypass by Rad26 Facilitates Transcription Coupled Nucleotide Excision Repair

(2019) Kathiresan Selvam et al.   JOURNAL OF MOLECULAR BIOLOGY

Cockayne syndrome group B deficiency reduces H3K9me3 chromatin remodeler SETDB1 and exacerbates cellular aging

(2019) Jong-Hyuk Lee et al.   NUCLEIC ACIDS RESEARCH

Leo1 is essential for the dynamic regulation of heterochromatin and gene expression during cellular quiescence

(2019) Eriko Oya et al.   Epigenetics & Chromatin

DNA Damage and Associated DNA Repair Defects in Disease and Premature Aging

(2019) Vinod Tiwari et al.   AMERICAN JOURNAL OF HUMAN GENETICS

The DNA damage response to transcription stress

(2019) Hannes Lans et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Mechanistic insights into the regulation of transcription and transcription-coupled DNA repair by Cockayne syndrome protein B

(2018) Erica L Boetefuer et al.   NUCLEIC ACIDS RESEARCH

Poly(ADP-ribose) polymerase 1 (PARP1) promotes oxidative stress–induced association of Cockayne syndrome group B protein with chromatin

(2018) Erica L Boetefuer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cockayne’s Syndrome A and B Proteins Regulate Transcription Arrest after Genotoxic Stress by Promoting ATF3 Degradation

(2017) Alexey Epanchintsev et al.   MOLECULAR CELL

Structural basis for the initiation of eukaryotic transcription-coupled DNA repair

(2017) Jun Xu et al.   NATURE

Elements That Regulate the DNA Damage Response of Proteins Defective in Cockayne Syndrome

(2016) Teruaki Iyama et al.   JOURNAL OF MOLECULAR BIOLOGY

Overexpression of parkin rescues the defective mitochondrial phenotype and the increased apoptosis of Cockayne Syndrome A cells

(2016) Barbara Pascucci et al.   Oncotarget

CTCF: an architectural protein bridging genome topology and function

(2014) Chin-Tong Ong et al.   NATURE REVIEWS GENETICS

CSB interacts with SNM1A and promotes DNA interstrand crosslink processing

(2014) Teruaki Iyama et al.   NUCLEIC ACIDS RESEARCH

Mitochondrial reactive oxygen species are scavenged by Cockayne syndrome B protein in human fibroblasts without nuclear DNA damage

(2014) James E. Cleaver et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dysregulation of gene expression as a cause of Cockayne syndrome neurological disease

(2014) Yuming Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Sequence-Specific Transcription Factor c-Jun Targets Cockayne Syndrome Protein B to Regulate Transcription and Chromatin Structure

(2014) Robert J. Lake et al.   PLoS Genetics

Transcription Recovery after DNA Damage Requires Chromatin Priming by the H3.3 Histone Chaperone HIRA

(2013) Salomé Adam et al.   CELL

Enhanced Chromatin Dynamics by FACT Promotes Transcriptional Restart after UV-Induced DNA Damage

(2013) Christoffel Dinant et al.   MOLECULAR CELL

Histone Methyltransferase DOT1L Drives Recovery of Gene Expression after a Genotoxic Attack

(2013) Valentyn Oksenych et al.   PLoS Genetics

Genome-wide Studies of CCCTC-binding Factor (CTCF) and Cohesin Provide Insight into Chromatin Structure and Regulation: FIGURE 1.

(2012) Bum-Kyu Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cockayne syndrome group B protein prevents the accumulation of damaged mitochondria by promoting mitochondrial autophagy

(2012) Morten Scheibye-Knudsen et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The Molecular Basis of CRL4DDB2/CSA Ubiquitin Ligase Architecture, Targeting, and Activation

(2011) Eric S. Fischer et al.   CELL

CSA and CSB proteins interact with p53 and regulate its Mdm2-dependent ubiquitination

(2011) Paolo Latini et al.   CELL CYCLE

Diverse Roles of RNA Polymerase II-associated Factor 1 Complex in Different Subpathways of Nucleotide Excision Repair

(2011) Danielle Tatum et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

8-Oxo-7,8-dihydroguanine in DNA does not constitute a barrier to transcription, but is converted into transcription-blocking damage by OGG1

(2011) Nataliya Kitsera et al.   NUCLEIC ACIDS RESEARCH

Cockayne syndrome group B protein promotes mitochondrial DNA stability by supporting the DNA repair association with the mitochondrial membrane

(2010) Maria D. Aamann et al.   FASEB JOURNAL

Proteins of nucleotide and base excision repair pathways interact in mitochondria to protect from loss of subcutaneous fat, a hallmark of aging

(2010) York Kamenisch et al.   JOURNAL OF EXPERIMENTAL MEDICINE

A Ubiquitin-Binding Domain in Cockayne Syndrome B Required for Transcription-Coupled Nucleotide Excision Repair

(2010) Roy Anindya et al.   MOLECULAR CELL

UV-Induced Association of the CSB Remodeling Protein with Chromatin Requires ATP-Dependent Relief of N-Terminal Autorepression

(2010) Robert J. Lake et al.   MOLECULAR CELL

Nucleic Acid Binding Activity of Human Cockayne Syndrome B Protein and Identification of Ca2+ as a Novel Metal Cofactor

(2009) Brian R. Berquist et al.   JOURNAL OF MOLECULAR BIOLOGY

Genome-Wide Analysis of Factors Affecting Transcription Elongation and DNA Repair: A New Role for PAF and Ccr4-Not in Transcription-Coupled Repair

(2009) Hélène Gaillard et al.   PLoS Genetics

Transcription-coupled DNA repair: two decades of progress and surprises

(2008) Philip C. Hanawalt et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY