The conserved sex regulator DMRT1 recruits SOX9 in sexual cell fate reprogramming

Dissecting Cell Lineage Specification and Sex Fate Determination in Gonadal Somatic Cells Using Single-Cell Transcriptomics

(2019) Isabelle Stévant et al.   Cell Reports

CBX2 is required to stabilize the testis pathway by repressing Wnt signaling

(2019) S. Alexandra Garcia-Moreno et al.   PLoS Genetics

Sex reversal following deletion of a single distal enhancer ofSox9

(2018) Nitzan Gonen et al.   SCIENCE

Gonadal supporting cells acquire sex-specific chromatin landscapes during mammalian sex determination

(2018) S. Alexandra Garcia-Moreno et al.   DEVELOPMENTAL BIOLOGY

Functional Analysis of Nuclear Estrogen Receptors in Zebrafish Reproduction by Genome Editing Approach

(2017) Huijie Lu et al.   ENDOCRINOLOGY

Vertebrate sex determination: evolutionary plasticity of a fundamental switch

(2017) Blanche Capel   NATURE REVIEWS GENETICS

In mammalian foetal testes, SOX9 regulates expression of its target genes by binding to genomic regions with conserved signatures

(2017) Massilva Rahmoun et al.   NUCLEIC ACIDS RESEARCH

Sox9 and Sox8 protect the adult testis from male-to-female genetic reprogramming and complete degeneration

(2016) Francisco J Barrionuevo et al.   eLife

Pioneer Transcription Factors Target Partial DNA Motifs on Nucleosomes to Initiate Reprogramming

(2015) Abdenour Soufi et al.   CELL

Sexual Cell-Fate Reprogramming in the Ovary by DMRT1

(2015) Robin E. Lindeman et al.   CURRENT BIOLOGY

Cell fate commitment during mammalian sex determination

(2015) Yi-Tzu Lin et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

An ancient protein-DNA interaction underlying metazoan sex determination

(2015) Mark W Murphy et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

An ancient protein-DNA interaction underlying metazoan sex determination

(2015) Mark W Murphy et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

DMRT1 Protects Male Gonadal Cells from Retinoid-Dependent Sexual Transdifferentiation

(2014) Anna Minkina et al.   DEVELOPMENTAL CELL

The transcription factor FOXL2 mobilizes estrogen signaling to maintain the identity of ovarian granulosa cells

(2014) Adrien Georges et al.   eLife

A MicroRNA (mmu-miR-124) Prevents Sox9 Expression in Developing Mouse Ovarian Cells1

(2013) Francisca M. Real et al.   BIOLOGY OF REPRODUCTION

Interaction between DMRT1 function and genetic background modulates signaling and pluripotency to control tumor susceptibility in the fetal germ line

(2013) Anthony D. Krentz et al.   DEVELOPMENTAL BIOLOGY

Building the mammalian testis: origins, differentiation, and assembly of the component cell populations

(2013) T. Svingen et al.   GENES & DEVELOPMENT

Fine Time Course Expression Analysis Identifies Cascades of Activation and Repression and Maps a Putative Regulator of Mammalian Sex Determination

(2013) Steven C. Munger et al.   PLoS Genetics

Sox9 and Sox8 Are Required for Basal Lamina Integrity of Testis Cords and for Suppression of FOXL2 During Embryonic Testis Development in Mice1

(2012) Ina Georg et al.   BIOLOGY OF REPRODUCTION

Sex and the singular DM domain: insights into sexual regulation, evolution and plasticity

(2012) Clinton K. Matson et al.   NATURE REVIEWS GENETICS

Temporal Transcriptional Profiling of Somatic and Germ Cells Reveals Biased Lineage Priming of Sexual Fate in the Fetal Mouse Gonad

(2012) Samantha A. Jameson et al.   PLoS Genetics

Dmrt1 mutation causes a male-to-female sex reversal after the sex determination by Dmy in the medaka

(2011) Haruo Masuyama et al.   CHROMOSOME RESEARCH

XY Sox9 embryonic loss-of-function mouse mutants show complete sex reversal and produce partially fertile XY oocytes

(2011) Rowena Lavery et al.   DEVELOPMENTAL BIOLOGY

DMRT1 prevents female reprogramming in the postnatal mammalian testis

(2011) Clinton K. Matson et al.   NATURE

FOXL2 versus SOX9: A lifelong “battle of the sexes”

(2010) Reiner A. Veitia   BIOESSAYS

Direct Reprogramming of Fibroblasts into Functional Cardiomyocytes by Defined Factors

(2010) Masaki Ieda et al.   CELL

A mouse tool for conditional mutagenesis in ovarian granulosa cells

(2010) Beatrice Grabner et al.   GENESIS

Generation of transgenic mice for conditional overexpression of Sox9

(2010) Youngwoo Kim et al.   JOURNAL OF BONE AND MINERAL METABOLISM

Direct conversion of fibroblasts to functional neurons by defined factors

(2010) Thomas Vierbuchen et al.   NATURE

Genome-wide analysis of DNA binding and transcriptional regulation by the mammalian Doublesex homolog DMRT1 in the juvenile testis

(2010) M. W. Murphy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Smad3 Is Required for Normal Follicular Follicle-Stimulating Hormone Responsiveness in the Mouse1

(2009) Xiaoyan Gong et al.   BIOLOGY OF REPRODUCTION

Somatic Sex Reprogramming of Adult Ovaries to Testes by FOXL2 Ablation

(2009) N. Henriette Uhlenhaut et al.   CELL

The avian Z-linked gene DMRT1 is required for male sex determination in the chicken

(2009) Craig A. Smith et al.   NATURE

Comprehensive Mapping of Long-Range Interactions Reveals Folding Principles of the Human Genome

(2009) E. Lieberman-Aiden et al.   SCIENCE

In vivo reprogramming of adult pancreatic exocrine cells to β-cells

(2008) Qiao Zhou et al.   NATURE

Sex determination involves synergistic action of SRY and SF1 on a specific Sox9 enhancer

(2008) Ryohei Sekido et al.   NATURE