Chronic valproic acid administration enhances oxidative stress, upregulates IL6 and downregulates Nrf2, Glut1 and Glut4 in rat’s liver and brain

Chronic Valproic Acid Administration Increases Plasma, Liver, and Brain Ammonia Concentration and Suppresses Glutamine Synthetase Activity

(2020) Abdelnaser A. Badawy et al.   Brain Sciences

Adverse placental effects of valproic acid: Studies in perfused human placentas

(2018) Miriam Rubinchik-Stern et al.   EPILEPSIA

Valproic Acid Attenuates Traumatic Brain Injury-Induced Inflammation in Vivo: Involvement of Autophagy and the Nrf2/ARE Signaling Pathway

(2018) Xiangrong Chen et al.   Frontiers in Molecular Neuroscience

Effects of Valproic Acid on Cerebral Nutrient Carriers' Expression in the Rat

(2018) Aniv Mann Brukner et al.   Frontiers in Pharmacology

Increased expression of fatty acid synthase and acetyl-CoA carboxylase in the prefrontal cortex and cerebellum in the valproic acid model of autism

(2016) Jianling Chen et al.   Experimental and Therapeutic Medicine

Ammonia as a Potential Neurotoxic Factor in Alzheimer's Disease

(2016) Aida Adlimoghaddam et al.   Frontiers in Molecular Neuroscience

Valproate modulates glucose metabolism in patients with epilepsy after first exposure

(2015) Aleksei Rakitin et al.   EPILEPSIA

Hypoglycemic, antilipidemic and antioxidant effects of valproic acid in alloxan-induced diabetic rats

(2015) Abidemi J. Akindele et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Role of Nrf2 activation and NF-κB inhibition in valproic acid induced hepatotoxicity and in diammonium glycyrrhizinate induced protection in mice

(2014) Jing Jin et al.   FOOD AND CHEMICAL TOXICOLOGY

Relation entre les concentrations plasmatiques d’acide valproïque et la survenue d’une hépatotoxicité

(2011) H. Ghozzi et al.   REVUE NEUROLOGIQUE

Glutathione depletion by valproic acid in sandwich-cultured rat hepatocytes: Role of biotransformation and temporal relationship with onset of toxicity

(2011) Tony K.L. Kiang et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

A review of valproate in psychiatric practice

(2009) Peter M Haddad et al.   Expert Opinion on Drug Metabolism & Toxicology

Effect of valproic acid on body weight, food intake, physical activity and hormones: results of a randomized controlled trial

(2008) CK Martin et al.   JOURNAL OF PSYCHOPHARMACOLOGY