A novel dual agonist of glucagon-like peptide-1 receptors and neuropeptide Y2 receptors attenuates fentanyl taking and seeking in male rats

Design and Evaluation of Peptide Dual-Agonists of GLP-1 and NPY2 Receptors for Glucoregulation and Weight Loss with Mitigated Nausea and Emesis

(2021) Brandon T. Milliken et al.   JOURNAL OF MEDICINAL CHEMISTRY

Opioid use disorder

(2020) John Strang et al.   Nature Reviews Disease Primers

Fentanyl self-administration impacts brain immune responses in male Sprague-Dawley rats

(2020) Chiomah Ezeomah et al.   BRAIN BEHAVIOR AND IMMUNITY

A novel mouse model of glucagon‐like peptide‐1 receptor expression: a look at the brain

(2020) Devon L. Graham et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Glucagon-like peptide-1 receptor regulation of basal dopamine transporter activity is species-dependent

(2020) Mathias E. Jensen et al.   NEUROCHEMISTRY INTERNATIONAL

Drug and Opioid-Involved Overdose Deaths — United States, 2017–2018

(2020) Nana Wilson et al.   MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT

Long-term treatment with a glucagon-like peptide-1 receptor agonist reduces ethanol intake in male and female rats

(2020) Daniel Vallöf et al.   Translational Psychiatry

Central GLP-1 receptors: Novel molecular targets for cocaine use disorder

(2019) N.S. Hernandez et al.   PHYSIOLOGY & BEHAVIOR

Sex differences in opioid reinforcement under a fentanyl vs. food choice procedure in rats

(2019) E. Andrew Townsend et al.   NEUROPSYCHOPHARMACOLOGY

Efficacy and safety of a monthly buprenorphine depot injection for opioid use disorder: a multicentre, randomised, double-blind, placebo-controlled, phase 3 trial

(2019) Barbara R Haight et al.   LANCET

The role of orexin-1 receptor signaling in demand for the opioid fentanyl

(2019) Jennifer E. Fragale et al.   NEUROPSYCHOPHARMACOLOGY

Glucagon-like peptide-1 receptor activation in the ventral tegmental area attenuates cocaine seeking in rats

(2018) Nicole S. Hernandez et al.   NEUROPSYCHOPHARMACOLOGY

Fentanyl: Receptor pharmacology, abuse potential, and implications for treatment

(2018) Sandra D. Comer et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Prevention and Treatment of Opioid Misuse and Addiction

(2018) Nora D. Volkow et al.   JAMA Psychiatry

PYY(3-36) and exendin-4 reduce food intake and activate neuronal circuits in a synergistic manner in mice

(2018) Marina Kjaergaard et al.   NEUROPEPTIDES

GLP-1 acts on habenular avoidance circuits to control nicotine intake

(2017) Luis M Tuesta et al.   NATURE NEUROSCIENCE

The glucagon-like peptide 1 receptor agonist Exendin-4 decreases relapse-like drinking in socially housed mice

(2017) Morgane Thomsen et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Central GLP-1 receptor activation modulates cocaine-evoked phasic dopamine signaling in the nucleus accumbens core

(2017) Samantha M. Fortin et al.   PHYSIOLOGY & BEHAVIOR

Effects of the GLP-1 Agonist Exendin-4 on Intravenous Ethanol Self-Administration in Mice

(2016) Gunnar Sørensen et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Central & peripheral glucagon-like peptide-1 receptor signaling differentially regulate addictive behaviors

(2016) Sunil Sirohi et al.   PHYSIOLOGY & BEHAVIOR

Glucagon-Like Peptide-1 Receptor Activation in the Ventral Tegmental Area Decreases the Reinforcing Efficacy of Cocaine

(2015) Heath D Schmidt et al.   NEUROPSYCHOPHARMACOLOGY

The glucagon-like peptide 1 (GLP-1) receptor agonist exendin-4 reduces cocaine self-administration in mice

(2015) Gunnar Sørensen et al.   PHYSIOLOGY & BEHAVIOR

Distribution and characterisation of Glucagon-like peptide-1 receptor expressing cells in the mouse brain

(2015) Simon C. Cork et al.   Molecular Metabolism

Casein Kinase 1δ/ε Inhibitor PF-5006739 Attenuates Opioid Drug-Seeking Behavior

(2014) Travis T. Wager et al.   ACS Chemical Neuroscience

Effects of PYY3–36 and GLP-1 on energy intake, energy expenditure, and appetite in overweight men

(2014) Julie Berg Schmidt et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Rapid dopamine transmission within the nucleus accumbens: Dramatic difference between morphine and oxycodone delivery

(2014) Caitlin M. Vander Weele et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Compulsive-Like Responding for Opioid Analgesics in Rats with Extended Access

(2014) Carrie L Wade et al.   NEUROPSYCHOPHARMACOLOGY

Ligands of the neuropeptide Y Y2 receptor

(2013) Gopi Kumar Mittapalli et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

The Y2 receptor agonist PYY3–36 increases the behavioural response to novelty and acute dopaminergic drug challenge in mice

(2013) Ulrike Stadlbauer et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Gut Peptide GLP-1 and Its Analogue, Exendin-4, Decrease Alcohol Intake and Reward

(2013) Rozita H. Shirazi et al.   PLoS One

The Glucagon-Like Peptide 1 Analogue, Exendin-4, Attenuates the Rewarding Properties of Psychostimulant Drugs in Mice

(2013) Emil Egecioglu et al.   PLoS One

The Glucagon-Like Peptide 1 Analogue Exendin-4 Attenuates the Nicotine-Induced Locomotor Stimulation, Accumbal Dopamine Release, Conditioned Place Preference as well as the Expression of Locomotor Sensitization in Mice

(2013) Emil Egecioglu et al.   PLoS One

Donepezil, an acetylcholinesterase inhibitor, attenuates nicotine self-administration and reinstatement of nicotine seeking in rats

(2012) Blake A. Kimmey et al.   ADDICTION BIOLOGY

Possible Mechanisms of Circulating PYY-Induced Satiation in Male Rats

(2012) Ulrike Stadlbauer et al.   ENDOCRINOLOGY

Glucagon-like peptide-1 in the rat brain: Distribution of expression and functional implication

(2012) Guibao Gu et al.   JOURNAL OF COMPARATIVE NEUROLOGY

GLP-1 analog attenuates cocaine reward

(2012) D L Graham et al.   MOLECULAR PSYCHIATRY

Interspecies Modeling and Prediction of Human Exenatide Pharmacokinetics

(2012) Ting Chen et al.   PHARMACEUTICAL RESEARCH

The glucagon-like peptide 1 analogue Exendin-4 attenuates alcohol mediated behaviors in rodents

(2012) Emil Egecioglu et al.   PSYCHONEUROENDOCRINOLOGY

Intracellular Signals Mediating the Food Intake-Suppressive Effects of Hindbrain Glucagon-like Peptide-1 Receptor Activation

(2011) Matthew R. Hayes et al.   Cell Metabolism

The Gut Hormones PYY3-36 and GLP-17-36 amide Reduce Food Intake and Modulate Brain Activity in Appetite Centers in Humans

(2011) Akila De Silva et al.   Cell Metabolism

Exogenous peptide YY3-36 and Exendin-4 further decrease food intake, whereas octreotide increases food intake in rats after Roux-en-Y gastric bypass

(2011) W K Fenske et al.   INTERNATIONAL JOURNAL OF OBESITY

The role of nausea in food intake and body weight suppression by peripheral GLP-1 receptor agonists, exendin-4 and liraglutide

(2011) Scott E. Kanoski et al.   NEUROPHARMACOLOGY

Comparative Effects of the Long-Acting GLP-1 Receptor Ligands, Liraglutide and Exendin-4, on Food Intake and Body Weight Suppression in Rats

(2011) Matthew R. Hayes et al.   Obesity

Uniform assessment and ranking of opioid Mu receptor binding constants for selected opioid drugs

(2011) Donna A. Volpe et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Peptide YY

(2011) Keval Chandarana et al.   Current Opinion in Endocrinology Diabetes and Obesity

Peptide hormones regulating appetite-focus on neuroimaging studies in humans

(2010) Haiko Schloegl et al.   DIABETES-METABOLISM RESEARCH AND REVIEWS

Therapeutic potential of neuropeptide Y (NPY) receptor ligands

(2010) Shaun P. Brothers et al.   EMBO Molecular Medicine

Efficacy and safety of exenatide once weekly versus sitagliptin or pioglitazone as an adjunct to metformin for treatment of type 2 diabetes (DURATION-2): a randomised trial

(2010) Richard M Bergenstal et al.   LANCET

Effects of Exendin-4 Alone and With Peptide YY3–36 on Food Intake and Body Weight in Diet-Induced Obese Rats

(2010) Roger D. Reidelberger et al.   Obesity

Role of the glucagon-like-peptide-1 receptor in the control of energy balance

(2010) Matthew R. Hayes et al.   PHYSIOLOGY & BEHAVIOR

Self-administration of cocaine, cannabis and heroin in the human laboratory: benefits and pitfalls

(2008) Margaret Haney   ADDICTION BIOLOGY

The role of peptide YY in appetite regulation and obesity

(2008) Efthimia Karra et al.   JOURNAL OF PHYSIOLOGY-LONDON

Controversies in translational research: drug self-administration

(2008) Margaret Haney et al.   PSYCHOPHARMACOLOGY

PYY(3–36) induces Fos in the arcuate nucleus and in both catecholaminergic and non-catecholaminergic neurons in the nucleus tractus solitarius of rats

(2007) J.E. Blevins et al.   PEPTIDES