Protective mechanisms of resveratrol against methotrexate-induced renal damage may involve BCRP/ABCG2

Resveratrol restored Nrf2 function, reduced renal inflammation, and mitigated hypertension in spontaneously hypertensive rats

(2015) Apurva A. Javkhedkar et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Resveratrol and cancer: Challenges for clinical translation

(2015) Chandra K. Singh et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Resveratrol ameliorates cisplatin-induced oxidative injury in New Zealand rabbits

(2015) Yilmaz Cigremis et al.   CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY

Chemosensitizing and nephroprotective effect of resveratrol in cisplatin –treated animals

(2015) Abdel-Moneim M Osman et al.   Cancer Cell International

Modification of Antitumor Immunity and Tumor Microenvironment by Resveratrol in Mouse Renal Tumor Model

(2015) Liang Chen et al.   CELL BIOCHEMISTRY AND BIOPHYSICS

Effects of pentoxifylline and alpha lipoic acid on methotrexate-induced damage in liver and kidney of rats

(2015) Ilkay Armagan et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Mechanisms of Thymoquinone Hepatorenal Protection in Methotrexate-Induced Toxicity in Rats

(2015) Azza A. K. El-Sheikh et al.   MEDIATORS OF INFLAMMATION

Resveratrol attenuates lipopolysaccharide-induced acute kidney injury by suppressing inflammation driven by macrophages

(2015) Liang Chen et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Organ-Protective Effects of Red Wine Extract, Resveratrol, in Oxidative Stress-Mediated Reperfusion Injury

(2015) Fu-Chao Liu et al.   Oxidative Medicine and Cellular Longevity

Resveratrol: A Focus on Several Neurodegenerative Diseases

(2015) Ester Tellone et al.   Oxidative Medicine and Cellular Longevity

An Organ System Approach to Explore the Antioxidative, Anti-Inflammatory, and Cytoprotective Actions of Resveratrol

(2015) Ashim Malhotra et al.   Oxidative Medicine and Cellular Longevity

Properties of Resveratrol:In VitroandIn VivoStudies about Metabolism, Bioavailability, and Biological Effects in Animal Models and Humans

(2015) J. Gambini et al.   Oxidative Medicine and Cellular Longevity

Resveratrol Rescues Kidney Mitochondrial Function Following Hemorrhagic Shock

(2015) Hao Wang et al.   SHOCK

Pioglitazone ameliorates methotrexate-induced renal endothelial dysfunction via amending detrimental changes in some antioxidant parameters, systemic cytokines and Fas production

(2015) Sahar M. El-Gowilly et al.   VASCULAR PHARMACOLOGY

Nephroprotective Role of Resveratrol and Ursolic Acid in Aristolochic Acid Intoxicated Zebrafish

(2015) Yu-Ju Ding et al.   Toxins

Role of the Breast Cancer Resistance Protein (BCRP/ABCG2) in Drug Transport—an Update

(2014) Qingcheng Mao et al.   AAPS Journal

Structure and function of BCRP, a broad specificity transporter of xenobiotics and endobiotics

(2014) Márton Jani et al.   ARCHIVES OF TOXICOLOGY

Resveratrol protects against arsenic trioxide-induced oxidative damage through maintenance of glutathione homeostasis and inhibition of apoptotic progression

(2014) Chengzhi Chen et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

Protective effect of peroxisome proliferator activator receptor (PPAR)-α and -γ ligands against methotrexate-induced nephrotoxicity

(2014) Mohamed A. Ibrahim et al.   IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY

Multi-drug resistance protein (Mrp) 3 may be involved in resveratrol protection against methotrexate-induced testicular damage

(2014) Azza A.K. El-Sheikh et al.   LIFE SCIENCES

Hepatic Sulfotransferase as a Nephropreventing Target by Suppression of the Uremic Toxin Indoxyl Sulfate Accumulation in Ischemic Acute Kidney Injury

(2014) Hideyuki Saito et al.   TOXICOLOGICAL SCIENCES

Nitric oxide system and diabetic nephropathy

(2014) Bruno Dellamea et al.   Diabetology & Metabolic Syndrome

Resveratrol Increases Nephrin and Podocin Expression and Alleviates Renal Damage in Rats Fed a High-Fat Diet

(2014) Qing-Rong Pan et al.   Nutrients

Molecular Basis for Pharmacokinetics and Pharmacodynamics of Methotrexate in Rheumatoid Arthritis Therapy

(2013) Katsuhisa Inoue et al.   Drug Metabolism and Pharmacokinetics

Resveratrol ameliorates methotrexate-induced hepatotoxicity in rats via inhibition of lipid peroxidation

(2013) S. Dalaklioglu et al.   HUMAN & EXPERIMENTAL TOXICOLOGY

Methotrexate: New Uses for an Old Drug

(2013) Philip J. Hashkes et al.   JOURNAL OF PEDIATRICS

Renal Protective Effects of Resveratrol

(2013) Munehiro Kitada et al.   Oxidative Medicine and Cellular Longevity

Interaction of immunosuppressive drugs with human organic anion transporter (OAT) 1 and OAT3, and multidrug resistance-associated protein (MRP) 2 and MRP4

(2013) Azza A.K. El-Sheikh et al.   Translational Research

Lack of ABCG2 Shortens Latency of BRCA1-Deficient Mammary Tumors and This Is Not Affected by Genistein or Resveratrol

(2012) S. A. L. Zander et al.   Cancer Prevention Research

Genetic risk factors for drug-induced liver injury in rheumatoid arthritis patients using low-dose methotrexate

(2012) Cristina Lucía Dávila-Fajardo et al.   PHARMACOGENOMICS

Interaction of hesperetin glucuronide conjugates with human BCRP, MRP2 and MRP3 as detected in membrane vesicles of overexpressing baculovirus-infected Sf9 cells

(2011) Walter Brand et al.   BIOPHARMACEUTICS & DRUG DISPOSITION

Pathobiology and Prevention of Cancer Chemotherapy-Induced Bone Growth Arrest, Bone Loss, and Osteonecrosis

(2011) C. Fan et al.   CURRENT MOLECULAR MEDICINE

pH-Dependent Transport of Pemetrexed by Breast Cancer Resistance Protein

(2011) L. Li et al.   DRUG METABOLISM AND DISPOSITION

Resveratrol attenuates doxorubicin-induced cellular damage by modulating nitric oxide and apoptosis

(2010) Gulperi Oktem et al.   EXPERIMENTAL AND TOXICOLOGIC PATHOLOGY

Involvement of Breast Cancer Resistance Protein (BCRP1/ABCG2) in the Bioavailability and Tissue Distribution oftrans-Resveratrol in Knockout Mice

(2010) Irene Alfaras et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Multidrug Resistance Proteins Restrain the Intestinal Absorption of trans-Resveratrol in Rats

(2010) M. Emília Juan et al.   JOURNAL OF NUTRITION

Mechanisms underlying methotrexate-induced pulmonary toxicity

(2009) Youn-Jung Kim et al.   Expert Opinion On Drug Safety

Caspase Mediated Enhanced Apoptotic Action of Cyclophosphamide- and Resveratrol-Treated MCF-7 Cells

(2009) Neetu Singh et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Substrate-Dependent Breast Cancer Resistance Protein (Bcrp1/Abcg2)-Mediated Interactions: Consideration of Multiple Binding Sites in in Vitro Assay Design

(2008) N. Giri et al.   DRUG METABOLISM AND DISPOSITION

Mechanisms of renal anionic drug transport

(2008) Azza A.K. El-Sheikh et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Protective effect of resveratrol on acute endotoxemia-induced nephrotoxicity in rat through nitric oxide independent mechanism

(2008) Hichem Sebai et al.   FREE RADICAL RESEARCH

Effect of melatonin, curcumin, quercetin, and resveratrol on acute ferric nitrilotriacetate (Fe-NTA)-induced renal oxidative damage in rats

(2008) V Eybl et al.   HUMAN & EXPERIMENTAL TOXICOLOGY

Increasing Systemic Exposure of Methotrexate by Active Efflux Mediated by Multidrug Resistance-Associated Protein 3 (Mrp3/Abcc3)

(2008) Y. Kitamura et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Intestinal Breast Cancer Resistance Protein (BCRP)/Bcrp1 and Multidrug Resistance Protein 3 (MRP3)/Mrp3 Are Involved in the Pharmacokinetics of Resveratrol

(2008) K. van de Wetering et al.   MOLECULAR PHARMACOLOGY