Type 2 diabetes mellitus in older adults: clinical considerations and management
Published 2021 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Type 2 diabetes mellitus in older adults: clinical considerations and management
Authors
Keywords
-
Journal
Nature Reviews Endocrinology
Volume 17, Issue 9, Pages 534-548
Publisher
Springer Science and Business Media LLC
Online
2021-06-25
DOI
10.1038/s41574-021-00512-2
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Targeting Age-Dependent Functional and Metabolic Decline of Human Skeletal Muscle: The Geroprotective Role of Exercise, Myokine IL-6, and Vitamin D
- (2020) Clara Crescioli INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Mechanism of increased risk of insulin resistance in aging skeletal muscle
- (2020) Jian Shou et al. Diabetology & Metabolic Syndrome
- Use of SGLT2 Inhibitors in Older Adults: Scientific Evidence and Practical Aspects
- (2020) Joaquim Silva Custódio et al. DRUGS & AGING
- Severe Hypoglycemia and Risk of Falls in Type 2 Diabetes: The Atherosclerosis Risk in Communities (ARIC) Study
- (2020) Alexandra K. Lee et al. DIABETES CARE
- Sodium–glucose cotransporter type 2 inhibitors for the treatment of type 2 diabetes mellitus
- (2020) André J. Scheen Nature Reviews Endocrinology
- Diabetes in ageing: pathways for developing the evidence base for clinical guidance
- (2020) Medha N Munshi et al. Lancet Diabetes & Endocrinology
- 12. Older Adults: Standards of Medical Care in Diabetes—2021
- (2020) DIABETES CARE
- Falls among older adults with sarcopenia dwelling in nursing home or community: A meta-analysis
- (2019) Xiaoming Zhang et al. CLINICAL NUTRITION
- The Impact of Aging on Adipose Function and Adipokine Synthesis
- (2019) Peter Mancuso et al. Frontiers in Endocrinology
- Diabetes-Multimorbidity Combinations and Disability Among Middle-aged and Older Adults
- (2019) Ana R. Quiñones et al. JOURNAL OF GENERAL INTERNAL MEDICINE
- Hyperglycemia and metformin use are associated with B-vitamin deficiency and cognitive dysfunction in older adults
- (2019) Kirsty M Porter et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Treatment of Diabetes in Older Adults: An Endocrine Society* Clinical Practice Guideline
- (2019) Derek LeRoith et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- CONSENSUS STATEMENT BY THE AMERICAN ASSOCIATION OF CLINICAL ENDOCRINOLOGISTS AND AMERICAN COLLEGE OF ENDOCRINOLOGY ON THE COMPREHENSIVE TYPE 2 DIABETES MANAGEMENT ALGORITHM – 2019 EXECUTIVE SUMMARY
- (2019) Alan J. Garber et al. Endocrine Practice
- Therapeutic Inertia and the Legacy of Dysglycemia on the Microvascular and Macrovascular Complications of Diabetes
- (2019) Kamlesh Khunti et al. DIABETES CARE
- Sarcopenia: revised European consensus on definition and diagnosis
- (2019) Alfonso J Cruz-Jentoft et al. AGE AND AGEING
- Long-Term Weight Loss With Metformin or Lifestyle Intervention in the Diabetes Prevention Program Outcomes Study
- (2019) John W. Apolzan et al. ANNALS OF INTERNAL MEDICINE
- Effectiveness of a multimodal intervention in functionally impaired older people with type 2 diabetes mellitus
- (2019) Leocadio Rodriguez‐Mañas et al. Journal of Cachexia Sarcopenia and Muscle
- Body composition changes in diabetes and aging
- (2019) Mohammed E. Al-Sofiani et al. JOURNAL OF DIABETES AND ITS COMPLICATIONS
- Natural history of prediabetes in older adults from a population‐based longitudinal study
- (2019) Y. Shang et al. JOURNAL OF INTERNAL MEDICINE
- Sarcopenia and type 2 diabetes mellitus: a bidirectional relationship
- (2019) Jakub Mesinovic et al. Diabetes Metabolic Syndrome and Obesity-Targets and Therapy
- Effect of Linagliptin vs Glimepiride on Major Adverse Cardiovascular Outcomes in Patients With Type 2 Diabetes
- (2019) Julio Rosenstock et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Efficacy and safety of empagliflozin in older patients in the EMPA-REG OUTCOME® trial
- (2019) Pedro Monteiro et al. AGE AND AGEING
- Aging and stress induced β cell senescence and its implication in diabetes development
- (2019) Na Li et al. Aging-US
- Early Outcomes From the English National Health Service Diabetes Prevention Programme
- (2019) Jonathan Valabhji et al. DIABETES CARE
- The epidemiology of multimorbidity in primary care: a retrospective cohort study
- (2018) Anna Cassell et al. BRITISH JOURNAL OF GENERAL PRACTICE
- Cardiovascular outcome studies in type 2 diabetes: Comparison between SGLT2 inhibitors and GLP-1 receptor agonists
- (2018) André J. Scheen DIABETES RESEARCH AND CLINICAL PRACTICE
- IDF Diabetes Atlas: Global estimates of diabetes prevalence for 2017 and projections for 2045
- (2018) N.H. Cho et al. DIABETES RESEARCH AND CLINICAL PRACTICE
- Failing to meet the needs of generations of care home residents with diabetes: a review of the literature and a call for action
- (2018) A. J. Sinclair et al. DIABETIC MEDICINE
- Type 2 diabetes mellitus in older people: a brief statement of key principles of modern day management including the assessment of frailty. A national collaborative stakeholder initiative
- (2018) W. D. Strain et al. DIABETIC MEDICINE
- Prediabetes and Cardiovascular Disease
- (2018) Ben Brannick et al. ENDOCRINOLOGY AND METABOLISM CLINICS OF NORTH AMERICA
- Exercise or physical activity and cognitive function in adults with type 2 diabetes, insulin resistance or impaired glucose tolerance: a systematic review
- (2018) Ren Ru Zhao et al. European Review of Aging and Physical Activity
- Glycaemic control and treatment of type 2 diabetes in adults aged 75 years or older
- (2018) Antonio Rodriguez-Poncelas et al. INTERNATIONAL JOURNAL OF CLINICAL PRACTICE
- Insulin Resistance is Associated with Cognitive Decline Among Older Koreans with Normal Baseline Cognitive Function: A Prospective Community-Based Cohort Study
- (2018) Sung Hye Kong et al. Scientific Reports
- Cognitive Function and Falls in Older Adults With Type 2 Diabetes Mellitus
- (2018) Jennifer Blackwood Journal of Geriatric Physical Therapy
- Are we missing hypoglycaemia? Elderly patients with insulin-treated diabetes present to primary care frequently with non-specific symptoms associated with hypoglycaemia
- (2018) Suzy V. Hope et al. Primary Care Diabetes
- Obesity and type-2 diabetes as inducers of premature cellular senescence and ageing
- (2018) Dominick G. A. Burton et al. BIOGERONTOLOGY
- Age-Related Changes in Glucose Metabolism, Hyperglycemia, and Cardiovascular Risk
- (2018) Chee W. Chia et al. CIRCULATION RESEARCH
- Long-term Glycemic Control and Dementia Risk in Type 1 Diabetes
- (2018) Mary E. Lacy et al. DIABETES CARE
- Exercise training modalities in patients with type 2 diabetes mellitus: a systematic review and network meta-analysis
- (2018) Bei Pan et al. International Journal of Behavioral Nutrition and Physical Activity
- Cognitive Function Is Impaired in Patients with Recently Diagnosed Type 2 Diabetes, but Not Type 1 Diabetes
- (2018) Theresa van Gemert et al. Journal of Diabetes Research
- Personality traits and cognitive function in old-adults with type-2 diabetes
- (2018) Galit Weinstein et al. AGING & MENTAL HEALTH
- Effect of Liraglutide on Cardiovascular Outcomes in Elderly Patients: A Post Hoc Analysis of a Randomized Controlled Trial
- (2018) Matthew P. Gilbert et al. ANNALS OF INTERNAL MEDICINE
- Management of Hyperglycemia in Type 2 Diabetes, 2018. A Consensus Report by the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD)
- (2018) Melanie J. Davies et al. DIABETES CARE
- HbA1c, Insulin Resistance, and β-Cell Function in Relation to Cognitive Function in Type 2 Diabetes: The CAROLINA Cognition Substudy
- (2018) Jolien Janssen et al. DIABETES CARE
- Effects of Severe Hypoglycemia on Cardiovascular Outcomes and Death in the Veterans Affairs Diabetes Trial
- (2018) Stephen N. Davis et al. DIABETES CARE
- Effect of Linagliptin vs Placebo on Major Cardiovascular Events in Adults With Type 2 Diabetes and High Cardiovascular and Renal Risk
- (2018) Julio Rosenstock et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Dapagliflozin and Cardiovascular Outcomes in Type 2 Diabetes
- (2018) Stephen D. Wiviott et al. NEW ENGLAND JOURNAL OF MEDICINE
- Sarcopenia as a predictor of all-cause mortality among older nursing home residents: a systematic review and meta-analysis
- (2018) Xiaoming Zhang et al. BMJ Open
- Changes in adipose tissue cellular composition during obesity and aging as a cause of metabolic dysregulation
- (2017) Kari Martyniak et al. EXPERIMENTAL GERONTOLOGY
- Effect of moderate-intensity aerobic exercise on glycosylated haemoglobin among elderly patients with type 2 diabetes & peripheral neuropathy
- (2017) Snehil Dixit et al. INDIAN JOURNAL OF MEDICAL RESEARCH
- Frailty and sarcopenia - newly emerging and high impact complications of diabetes
- (2017) Alan J. Sinclair et al. JOURNAL OF DIABETES AND ITS COMPLICATIONS
- Sarcopenia: a potential cause and consequence of type 2 diabetes in Australia's ageing population?
- (2017) David Scott et al. MEDICAL JOURNAL OF AUSTRALIA
- Aerobic or Resistance Exercise, or Both, in Dieting Obese Older Adults
- (2017) Dennis T. Villareal et al. NEW ENGLAND JOURNAL OF MEDICINE
- Canagliflozin and Cardiovascular and Renal Events in Type 2 Diabetes
- (2017) Bruce Neal et al. NEW ENGLAND JOURNAL OF MEDICINE
- Type 2 Diabetes Mellitus and Impaired Renal Function Are Associated With Brain Alterations and Poststroke Cognitive Decline
- (2017) Einor Ben Assayag et al. STROKE
- The Associations among Insulin Resistance, Hyperglycemia, Physical Performance, Diabetes Mellitus, and Cognitive Function in Relatively Healthy Older Adults with Subtle Cognitive Dysfunction
- (2017) Hiroyuki Umegaki et al. Frontiers in Aging Neuroscience
- Efficacy and safety of metformin in the management of type 2 diabetes mellitus in older adults: a systematic review for the development of recommendations to reduce potentially inappropriate prescribing
- (2017) Lisa Schlender et al. BMC Geriatrics
- Glycemic Control and Functional Decline in Nursing Home Residents With Diabetes
- (2017) Amy Hsu et al. JAMA Internal Medicine
- Effects on the incidence of cardiovascular events of the addition of pioglitazone versus sulfonylureas in patients with type 2 diabetes inadequately controlled with metformin (TOSCA.IT): a randomised, multicentre trial
- (2017) Olga Vaccaro et al. Lancet Diabetes & Endocrinology
- Resistance Training for Glycemic Control, Muscular Strength, and Lean Body Mass in Old Type 2 Diabetic Patients: A Meta-Analysis
- (2017) JungHoon Lee et al. Diabetes Therapy
- Resistance Training for Glycemic Control, Muscular Strength, and Lean Body Mass in Old Type 2 Diabetic Patients: A Meta-Analysis
- (2017) JungHoon Lee et al. Diabetes Therapy
- A systematic review of medication non-adherence in persons with dementia or cognitive impairment
- (2017) Daisy Smith et al. PLoS One
- Muscle dysfunction in type 2 diabetes: a major threat to patient’s mobility and independence
- (2016) Lara Bianchi et al. ACTA DIABETOLOGICA
- Multimorbidity and mortality in older adults: A systematic review and meta-analysis
- (2016) Bruno Pereira Nunes et al. ARCHIVES OF GERONTOLOGY AND GERIATRICS
- Hypoglycaemia when adding sulphonylurea to metformin: a systematic review and network meta-analysis
- (2016) Stig Ejdrup Andersen et al. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
- Insulin resistance and sarcopenia: mechanistic links between common co-morbidities
- (2016) Mark E Cleasby et al. JOURNAL OF ENDOCRINOLOGY
- Association between telomere length and diabetes mellitus: A meta-analysis
- (2016) Jianfei Wang et al. JOURNAL OF INTERNATIONAL MEDICAL RESEARCH
- Frailty: An Emerging Public Health Priority
- (2016) Matteo Cesari et al. Journal of the American Medical Directors Association
- Glucose Levels and Risk of Frailty
- (2016) Oleg Zaslavsky et al. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
- Worldwide trends in diabetes since 1980: a pooled analysis of 751 population-based studies with 4·4 million participants
- (2016) LANCET
- Pharmacology and therapeutic implications of current drugs for type 2 diabetes mellitus
- (2016) Abd A. Tahrani et al. Nature Reviews Endocrinology
- Association between Depressive Symptoms and Cognitive Function in Persons with Diabetes Mellitus: A Systematic Review
- (2016) Sofia M. Danna et al. PLoS One
- Diabetes, hyperglycemia, and the burden of functional disability among older adults in a community-based study
- (2016) Job G Godino et al. Journal of Diabetes
- Sarcopenia, Frailty, and Diabetes in Older Adults
- (2016) Hak Chul Jang Diabetes & Metabolism Journal
- Hyperglycemia Is Associated with Impaired Muscle Quality in Older Men with Diabetes: The Korean Longitudinal Study on Health and Aging
- (2016) Ji Won Yoon et al. Diabetes & Metabolism Journal
- Determinants of new-onset diabetes in older adults–Results of a national cohort study
- (2015) Alan C. Tsai et al. CLINICAL NUTRITION
- Safety of antidiabetes medications: An update
- (2015) CJ Bailey CLINICAL PHARMACOLOGY & THERAPEUTICS
- Physical Function and Disability in Older Adults with Diabetes
- (2015) Nathalie de Rekeneire et al. CLINICS IN GERIATRIC MEDICINE
- Efficacy and Safety of Saxagliptin in Older Participants in the SAVOR-TIMI 53 Trial
- (2015) Lawrence A. Leiter et al. DIABETES CARE
- Preventing the progression to Type 2 diabetes mellitus in adults at high risk: A systematic review and network meta-analysis of lifestyle, pharmacological and surgical interventions
- (2015) John W. Stevens et al. DIABETES RESEARCH AND CLINICAL PRACTICE
- Efficacy and Tolerability of Sitagliptin Compared with Glimepiride in Elderly Patients with Type 2 Diabetes Mellitus and Inadequate Glycemic Control: A Randomized, Double-Blind, Non-Inferiority Trial
- (2015) Paul Hartley et al. DRUGS & AGING
- Relationship between glycated hemoglobin A1c and cognitive function in nondemented elderly patients with type 2 diabetes
- (2015) Lingning Huang et al. METABOLIC BRAIN DISEASE
- Empagliflozin, Cardiovascular Outcomes, and Mortality in Type 2 Diabetes
- (2015) Bernard Zinman et al. NEW ENGLAND JOURNAL OF MEDICINE
- Effects of Aerobic Exercise Based upon Heart Rate at Aerobic Threshold in Obese Elderly Subjects with Type 2 Diabetes
- (2015) Gian Pietro Emerenziani et al. International Journal of Endocrinology
- Low HbA1c and Increased Mortality Risk-is Frailty a Confounding Factor?
- (2015) Ahmed H Abdelhafiz et al. Aging and Disease
- Diabetes in older people: new insights and remaining challenges
- (2015) Alan Sinclair et al. Lancet Diabetes & Endocrinology
- Vitamins and Type 2 Diabetes Mellitus
- (2015) Roxana Valdes-Ramos et al. Endocrine Metabolic & Immune Disorders-Drug Targets
- Diabetes in Midlife and Cognitive Change Over 20 Years
- (2014) Andreea M. Rawlings et al. ANNALS OF INTERNAL MEDICINE
- Geroscience: Linking Aging to Chronic Disease
- (2014) Brian K. Kennedy et al. CELL
- Insulin Therapy in People With Type 2 Diabetes: Opportunities and Challenges?
- (2014) Philip Home et al. DIABETES CARE
- New IDF Guideline for managing type 2 diabetes in older people
- (2014) Trisha Dunning et al. DIABETES RESEARCH AND CLINICAL PRACTICE
- Type 2 diabetes is associated with low muscle mass in older adults
- (2014) Kyung-Soo Kim et al. Geriatrics & Gerontology International
- Skeletal muscle capillary density and microvascular function are compromised with aging and type 2 diabetes
- (2014) Bart B. L. Groen et al. JOURNAL OF APPLIED PHYSIOLOGY
- High Prevalence of Falls, Fear of Falling, and Impaired Balance in Older Adults with Pain in the United States: Findings from the 2011 National Health and Aging Trends Study
- (2014) Kushang V. Patel et al. JOURNAL OF THE AMERICAN GERIATRICS SOCIETY
- Incidence and Predictors of Multimorbidity in the Elderly: A Population-Based Longitudinal Study
- (2014) René Melis et al. PLoS One
- Effect of renal impairment on cognitive function during a 3-year follow up in elderly patients with type 2 diabetes: Association with microinflammation
- (2014) Takahiko Kawamura et al. Journal of Diabetes Investigation
- The Effect of Comorbid Illness and Functional Status on the Expected Benefits of Intensive Glucose Control in Older Patients with Type 2 Diabetes: A Decision Analysis
- (2013) Elbert S. Huang et al. ANNALS OF INTERNAL MEDICINE
- Relationship between blood pressure, cognitive function and education level in elderly patients with diabetes: A preliminary study
- (2013) J. Talfournier et al. DIABETES & METABOLISM
- Effects of Randomization to Intensive Glucose Control on Adverse Events, Cardiovascular Disease, and Mortality in Older Versus Younger Adults in the ACCORD Trial
- (2013) Michael E. Miller et al. DIABETES CARE
- The Prevalence of Presarcopenia in Asian Indian Individuals With and Without Type 2 Diabetes
- (2013) Viknesh Prabu Anbalagan et al. Diabetes Technology & Therapeutics
- Patients With Type 2 Diabetes Show a Greater Decline in Muscle Mass, Muscle Strength, and Functional Capacity With Aging
- (2013) Marika Leenders et al. Journal of the American Medical Directors Association
- Individualised treatment targets for elderly patients with type 2 diabetes using vildagliptin add-on or lone therapy (INTERVAL): a 24 week, randomised, double-blind, placebo-controlled study
- (2013) W David Strain et al. LANCET
- Frailty and diabetes
- (2013) Alan Sinclair et al. LANCET
- Midlife type 2 diabetes and poor glycaemic control as risk factors for cognitive decline in early old age: a post-hoc analysis of the Whitehall II cohort study
- (2013) Richard H Tuligenga et al. Lancet Diabetes & Endocrinology
- Metabolic outcomes of elderly patient populations initiating exenatide BID versus insulin glargine in an ambulatory care setting
- (2012) Manjiri Pawaskar et al. CURRENT MEDICAL RESEARCH AND OPINION
- Improvements in the Life Expectancy of Type 1 Diabetes: The Pittsburgh Epidemiology of Diabetes Complications Study Cohort
- (2012) R. G. Miller et al. DIABETES
- Glycosylated Hemoglobin and Functional Decline in Community-Dwelling Nursing Home-Eligible Elderly Adults with Diabetes Mellitus
- (2012) Celia K. Yau et al. JOURNAL OF THE AMERICAN GERIATRICS SOCIETY
- Diabetes in Older Adults: A Consensus Report
- (2012) M. Sue Kirkman et al. JOURNAL OF THE AMERICAN GERIATRICS SOCIETY
- Prevalence of Frailty in Community-Dwelling Older Persons: A Systematic Review
- (2012) Rose M. Collard et al. JOURNAL OF THE AMERICAN GERIATRICS SOCIETY
- Diabetes Mellitus in Older People: Position Statement on behalf of the International Association of Gerontology and Geriatrics (IAGG), the European Diabetes Working Party for Older People (EDWPOP), and the International Task Force of Experts in Diabetes
- (2012) Alan Sinclair et al. Journal of the American Medical Directors Association
- Healthy life expectancy for 187 countries, 1990–2010: a systematic analysis for the Global Burden Disease Study 2010
- (2012) Joshua A Salomon et al. LANCET
- Frequent Hypoglycemia Among Elderly Patients With Poor Glycemic Control
- (2011) Medha N. Munshi ARCHIVES OF INTERNAL MEDICINE
- Correlates of Quality of Life in Older Adults With Diabetes
- (2011) Neda Laiteerapong et al. DIABETES CARE
- Prevalence and Determinant Factors of Sarcopenia in Patients With Type 2 Diabetes: The Korean Sarcopenic Obesity Study (KSOS)
- (2010) T. N. Kim et al. DIABETES CARE
- Association of Diabetes, Comorbidities, and A1C With Functional Disability in Older Adults: Results from the National Health and Nutrition Examination Survey (NHANES), 1999-2006
- (2010) R. R. Kalyani et al. DIABETES CARE
- Risk of Acute Myocardial Infarction, Stroke, Heart Failure, and Death in Elderly Medicare Patients Treated With Rosiglitazone or Pioglitazone
- (2010) David J. Graham et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Determinants of Severe Hypoglycemia Complicating Type 2 Diabetes: The Fremantle Diabetes Study
- (2010) Timothy M. E. Davis et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Severe Hypoglycemia and Risks of Vascular Events and Death
- (2010) Sophia Zoungas et al. NEW ENGLAND JOURNAL OF MEDICINE
- Stress hormones: physiological stress and regulation of metabolism
- (2009) Ioannis Kyrou et al. CURRENT OPINION IN PHARMACOLOGY
- Age, Obesity, and Sex Effects on Insulin Sensitivity and Skeletal Muscle Mitochondrial Function
- (2009) H. Karakelides et al. DIABETES
- Excessive Loss of Skeletal Muscle Mass in Older Adults With Type 2 Diabetes
- (2009) S. W. Park et al. DIABETES CARE
- Physical Inactivity and Obesity Underlie the Insulin Resistance of Aging
- (2009) F. Amati et al. DIABETES CARE
- Obesity in the Elderly Diabetic Patient: Is weight loss beneficial? No
- (2009) I. Kyrou et al. DIABETES CARE
- Connecting obesity, aging and diabetes
- (2009) Rexford S. Ahima NATURE MEDICINE
- Hypoglycaemia: An overview
- (2009) Alex J. Graveling et al. Primary Care Diabetes
- The prevention of type 2 diabetes
- (2008) Jill P Crandall et al. Nature clinical practice. Endocrinology & metabolism
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now