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Title
Advancing therapy for osteosarcoma
Authors
Keywords
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Journal
Nature Reviews Clinical Oncology
Volume 18, Issue 10, Pages 609-624
Publisher
Springer Science and Business Media LLC
Online
2021-06-16
DOI
10.1038/s41571-021-00519-8
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Note: Only part of the references are listed.- Radiotherapy-exposed CD8+ and CD4+ neoantigens enhance tumor control
- (2021) Claire Lhuillier et al. JOURNAL OF CLINICAL INVESTIGATION
- Antitumor Activity and Safety of Trastuzumab Deruxtecan in Patients With HER2-Low–Expressing Advanced Breast Cancer: Results From a Phase Ib Study
- (2020) Shanu Modi et al. JOURNAL OF CLINICAL ONCOLOGY
- Cabozantinib in patients with advanced Ewing sarcoma or osteosarcoma (CABONE): a multicentre, single-arm, phase 2 trial
- (2020) Antoine Italiano et al. LANCET ONCOLOGY
- Comprehensive analysis of chromothripsis in 2,658 human cancers using whole-genome sequencing
- (2020) Isidro Cortés-Ciriano et al. NATURE GENETICS
- Preclinical evaluation of the combination of AZD1775 and irinotecan against selected pediatric solid tumors: A Pediatric Preclinical Testing Consortium report
- (2020) E. Anders Kolb et al. PEDIATRIC BLOOD & CANCER
- Immuno-genomic landscape of osteosarcoma
- (2020) Chia-Chin Wu et al. Nature Communications
- Tumor secreted ANGPTL2 facilitates recruitment of neutrophils to the lung to promote lung pre-metastatic niche formation and targeting ANGPTL2 signaling affects metastatic disease
- (2020) Manish Charan et al. Oncotarget
- Phase II study of antidisialoganglioside antibody, dinutuximab, in combination with GM-CSF in patients with recurrent osteosarcoma (AOST1421): A report from the Children’s Oncology Group.
- (2020) Pooja Hingorani et al. JOURNAL OF CLINICAL ONCOLOGY
- Preliminary dose escalation results from a phase I/II, first-in-human study of MGC018 (anti-B7-H3 antibody-drug conjugate) in patients with advanced solid tumors.
- (2020) John D. Powderly et al. JOURNAL OF CLINICAL ONCOLOGY
- Nivolumab in children and young adults with relapsed or refractory solid tumours or lymphoma (ADVL1412): a multicentre, open-label, single-arm, phase 1–2 trial
- (2020) Kara L Davis et al. LANCET ONCOLOGY
- The Osteosarcoma Microenvironment: A Complex but Targetable Ecosystem
- (2020) Isabelle Corre et al. Cells
- How we approach Philadelphia chromosome‐positive acute lymphoblastic leukemia in children and young adults
- (2020) William B. Slayton et al. PEDIATRIC BLOOD & CANCER
- Chimeric Antigen Receptor T Cell Therapy for Pediatric B-ALL: Narrowing the Gap Between Early and Long-Term Outcomes
- (2020) Liora Schultz Frontiers in Immunology
- CXCL13/CXCR5 Interaction Facilitates VCAM-1-Dependent Migration in Human Osteosarcoma
- (2020) Ju-Fang Liu et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Expression and clinical implications of leucine‐rich repeat containing 15 (LRRC15) in osteosarcoma
- (2020) Juncheng Cui et al. JOURNAL OF ORTHOPAEDIC RESEARCH
- Preclinical Development of MGC018, a Duocarmycin-based Antibody-drug Conjugate Targeting B7-H3 for Solid Cancer
- (2020) Juniper A Scribner et al. MOLECULAR CANCER THERAPEUTICS
- Identification of Potential Therapeutic Targets and Immune Cell Infiltration Characteristics in Osteosarcoma Using Bioinformatics Strategy
- (2020) Jianfang Niu et al. Frontiers in Oncology
- ABBV-085, antibody-drug conjugate targeting LRRC15, is effective in osteosarcoma: A report by the Pediatric Preclinical Testing Consortium
- (2020) Pooja Hingorani et al. MOLECULAR CANCER THERAPEUTICS
- Single-cell RNA landscape of intratumoral heterogeneity and immunosuppressive microenvironment in advanced osteosarcoma
- (2020) Yan Zhou et al. Nature Communications
- Epigenetic modulation enhances immunotherapy for hepatocellular carcinoma
- (2019) Young K. Hong et al. CELLULAR IMMUNOLOGY
- CAR T cells targeting B7-H3, a Pan-Cancer Antigen, Demonstrate Potent Preclinical Activity Against Pediatric Solid Tumors and Brain Tumors
- (2019) Robbie G. Majzner et al. CLINICAL CANCER RESEARCH
- State-of-the-Art of Profiling Immune Contexture in the Era of Multiplexed Staining and Digital Analysis to Study Paraffin Tumor Tissues
- (2019) Edwin Parra et al. Cancers
- Aurora B kinase as a novel molecular target for inhibition the growth of osteosarcoma
- (2019) Zhenjiang Zhao et al. MOLECULAR CARCINOGENESIS
- First-in-Human, First-in-Class Phase I Trial of the Anti-CD47 Antibody Hu5F9-G4 in Patients With Advanced Cancers
- (2019) Branimir I. Sikic et al. JOURNAL OF CLINICAL ONCOLOGY
- A Phase 2 Study of Alisertib in Children with Recurrent/Refractory Solid Tumors or Leukemia: Children's Oncology Group Phase 1 and Pilot Consortium ADVL0921)
- (2019) Yael P. Mosse et al. CLINICAL CANCER RESEARCH
- First-in-human phase 1 study of ABBV-085, an antibody-drug conjugate (ADC) targeting LRRC15, in sarcomas and other advanced solid tumors.
- (2019) George D. Demetri et al. JOURNAL OF CLINICAL ONCOLOGY
- Sorafenib and Palbociclib Combination Regresses a Cisplatinum-resistant Osteosarcoma in a PDOX Mouse Model
- (2019) TAKASHI HIGUCHI et al. ANTICANCER RESEARCH
- Randomized Double-Blind Phase II Study of Regorafenib in Patients With Metastatic Osteosarcoma
- (2019) Lara E. Davis et al. JOURNAL OF CLINICAL ONCOLOGY
- Cell Adhesion Molecules and Their Roles and Regulation in the Immune and Tumor Microenvironment
- (2019) Heidi Harjunpää et al. Frontiers in Immunology
- Programmed cell death 1 (PD-1) targeting in patients with advanced osteosarcomas: results from the PEMBROSARC study
- (2019) A. Le Cesne et al. EUROPEAN JOURNAL OF CANCER
- Phase II trial of the glycoprotein non-metastatic B-targeted antibody–drug conjugate, glembatumumab vedotin (CDX-011), in recurrent osteosarcoma AOST1521: A report from the Children's Oncology Group
- (2019) Lisa M. Kopp et al. EUROPEAN JOURNAL OF CANCER
- Clinicopathological and prognostic values of ErbB receptor family amplification in primary osteosarcoma
- (2019) Zhen Huang et al. SCANDINAVIAN JOURNAL OF CLINICAL & LABORATORY INVESTIGATION
- Genomic Profiling of Childhood Tumor Patient-Derived Xenograft Models to Enable Rational Clinical Trial Design
- (2019) Jo Lynne Rokita et al. Cell Reports
- Methotrexate–Etoposide–Ifosfamide Compared with Doxorubicin–Cisplatin–Ifosfamide Chemotherapy in Osteosarcoma Treatment, Patients Aged 18–25 Years
- (2019) Perrine Marec-Berard et al. Journal of Adolescent and Young Adult Oncology
- Pazopanib in the Treatment of Bone Sarcomas: Clinical Experience
- (2019) Ninna Aggerholm-Pedersen et al. Translational Oncology
- Expression and therapeutic implications of cyclin-dependent kinase 4 (CDK4) in osteosarcoma
- (2018) Yubing Zhou et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Humanization of bone and bone marrow in an orthotopic site reveals new potential therapeutic targets in osteosarcoma
- (2018) Ferdinand Wagner et al. BIOMATERIALS
- Results of methotrexate-etoposide-ifosfamide based regimen (M-EI) in osteosarcoma patients included in the French OS2006/sarcome-09 study
- (2018) Nathalie Gaspar et al. EUROPEAN JOURNAL OF CANCER
- PD-1 axis expression in musculoskeletal tumors and antitumor effect of nivolumab in osteosarcoma model of humanized mouse
- (2018) Bingxin Zheng et al. Journal of Hematology & Oncology
- The landscape of genomic alterations across childhood cancers
- (2018) Susanne N. Gröbner et al. NATURE
- Positively selected enhancer elements endow osteosarcoma cells with metastatic competence
- (2018) James J Morrow et al. NATURE MEDICINE
- Anti-PD-1 therapy redirects macrophages from an M2 to an M1 phenotype inducing regression of OS lung metastases
- (2018) Pooja Dhupkar et al. Cancer Medicine
- Single-agent expansion cohort of lenvatinib (LEN) and combination dose-finding cohort of LEN + etoposide (ETP) + ifosfamide (IFM) in patients (pts) aged 2 to ≤25 years with relapsed/refractory osteosarcoma (OS).
- (2018) Nathalie Gaspar et al. JOURNAL OF CLINICAL ONCOLOGY
- Profiling targetable immune checkpoints in osteosarcoma
- (2018) Troy A McEachron et al. OncoImmunology
- A phase II study of eribulin in recurrent or refractory osteosarcoma: A report from the Children's Oncology Group
- (2018) Michael S. Isakoff et al. PEDIATRIC BLOOD & CANCER
- Src nuclear localization and its prognostic relevance in human osteosarcoma
- (2017) Enrica Urciuoli et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Pembrolizumab in advanced soft-tissue sarcoma and bone sarcoma (SARC028): a multicentre, two-cohort, single-arm, open-label, phase 2 trial
- (2017) Hussein A Tawbi et al. LANCET ONCOLOGY
- KLF4-dependent perivascular cell plasticity mediates pre-metastatic niche formation and metastasis
- (2017) Meera Murgai et al. NATURE MEDICINE
- A single dose of peripherally infused EGFRvIII-directed CAR T cells mediates antigen loss and induces adaptive resistance in patients with recurrent glioblastoma
- (2017) Donald M. O’Rourke et al. Science Translational Medicine
- Recurrent mutation of IGF signalling genes and distinct patterns of genomic rearrangement in osteosarcoma
- (2017) Sam Behjati et al. Nature Communications
- cFOS-SOX9 Axis Reprograms Bone Marrow-Derived Mesenchymal Stem Cells into Chondroblastic Osteosarcoma
- (2017) Yunlong He et al. Stem Cell Reports
- Effect of entinostat on NK cell-mediated cytotoxicity against osteosarcoma cells and osteosarcoma lung metastasis
- (2017) Simin Kiany et al. OncoImmunology
- Osteosarcoma enters a post genomic era with in silico opportunities: Generation of the High Dimensional Database for facilitating sarcoma biology research: A report from the Children's Oncology Group and the QuadW Foundation
- (2017) Jason Glover et al. PLoS One
- Whole-exome sequencing in osteosarcoma reveals important heterogeneity of genetic alterations
- (2016) M. Bousquet et al. ANNALS OF ONCOLOGY
- Gemcitabine and docetaxel in relapsed and unresectable high-grade osteosarcoma and spindle cell sarcoma of bone
- (2016) E. Palmerini et al. BMC CANCER
- Molecular Pathways: Targeting B7-H3 (CD276) for Human Cancer Immunotherapy
- (2016) E. Picarda et al. CLINICAL CANCER RESEARCH
- Outcome of Patients With Recurrent Osteosarcoma Enrolled in Seven Phase II Trials Through Children's Cancer Group, Pediatric Oncology Group, and Children's Oncology Group: Learning From the Past to Move Forward
- (2016) Joanne P. Lagmay et al. JOURNAL OF CLINICAL ONCOLOGY
- Comparison of MAPIE versus MAP in patients with a poor response to preoperative chemotherapy for newly diagnosed high-grade osteosarcoma (EURAMOS-1): an open-label, international, randomised controlled trial
- (2016) Neyssa M Marina et al. LANCET ONCOLOGY
- HHLA2, a member of the B7 family, is expressed in human osteosarcoma and is associated with metastases and worse survival
- (2016) Pratistha Koirala et al. Scientific Reports
- Immune infiltration and PD-L1 expression in the tumor microenvironment are prognostic in osteosarcoma
- (2016) Pratistha Koirala et al. Scientific Reports
- Augmented expression of MYC and/or MYCN protein defines highly aggressive MYC-driven neuroblastoma: a Children’s Oncology Group study
- (2015) L L Wang et al. BRITISH JOURNAL OF CANCER
- Methotrexate, Doxorubicin, and Cisplatin (MAP) Plus Maintenance Pegylated Interferon Alfa-2b Versus MAP Alone in Patients With Resectable High-Grade Osteosarcoma and Good Histologic Response to Preoperative MAP: First Results of the EURAMOS-1 Good Response Randomized Controlled Trial
- (2015) Stefan S. Bielack et al. JOURNAL OF CLINICAL ONCOLOGY
- Human Epidermal Growth Factor Receptor 2 (HER2) –Specific Chimeric Antigen Receptor–Modified T Cells for the Immunotherapy of HER2-Positive Sarcoma
- (2015) Nabil Ahmed et al. JOURNAL OF CLINICAL ONCOLOGY
- Osteosarcoma: Current Treatment and a Collaborative Pathway to Success
- (2015) Michael S. Isakoff et al. JOURNAL OF CLINICAL ONCOLOGY
- EGFR is not a major driver for osteosarcoma cell growth in vitro but contributes to starvation and chemotherapy resistance
- (2015) Florian Sevelda et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- Sorafenib and everolimus for patients with unresectable high-grade osteosarcoma progressing after standard treatment: a non-randomised phase 2 clinical trial
- (2015) Giovanni Grignani et al. LANCET ONCOLOGY
- Tumor-infiltrating lymphocytes for the treatment of metastatic cancer
- (2015) M.H. Geukes Foppen et al. Molecular Oncology
- A Sleeping Beauty forward genetic screen identifies new genes and pathways driving osteosarcoma development and metastasis
- (2015) Branden S Moriarity et al. NATURE GENETICS
- Rapid Protocol Enrollment in Osteosarcoma: A Report From the Children's Oncology Group
- (2015) Michael S. Isakoff et al. PEDIATRIC BLOOD & CANCER
- Targeting Glycoprotein NMB With Antibody-Drug Conjugate, Glembatumumab Vedotin, for the Treatment of Osteosarcoma
- (2015) Michael Roth et al. PEDIATRIC BLOOD & CANCER
- Exome sequencing of osteosarcoma reveals mutation signatures reminiscent of BRCA deficiency
- (2015) Michal Kovac et al. Nature Communications
- CD47 blockade inhibits tumor progression human osteosarcoma in xenograft models
- (2015) Ji-Feng Xu et al. Oncotarget
- Unscrambling the genomic chaos of osteosarcoma reveals extensive transcript fusion, recurrent rearrangements and frequent novel TP53 aberrations
- (2015) Susanne Lorenz et al. Oncotarget
- CD8+/FOXP3+-ratio in osteosarcoma microenvironment separates survivors from non-survivors: a multicenter validated retrospective study
- (2015) Benedikt Fritzsching et al. OncoImmunology
- Recurrent osteosarcoma with a single pulmonary metastasis: a multi-institutional review
- (2014) N C Daw et al. BRITISH JOURNAL OF CANCER
- HER-2 expression is not prognostic in osteosarcoma; a Children's Oncology Group prospective biology study
- (2014) Sarah Gorlick et al. PEDIATRIC BLOOD & CANCER
- A summary of the osteosarcoma banking efforts: A report from the Children's Oncology Group and the QuadW Foundation
- (2014) Jason Glover et al. PEDIATRIC BLOOD & CANCER
- Initial testing (stage 1) of glembatumumab vedotin (CDX-011) by the pediatric preclinical testing program
- (2014) E. Anders Kolb et al. PEDIATRIC BLOOD & CANCER
- Complementary genomic approaches highlight the PI3K/mTOR pathway as a common vulnerability in osteosarcoma
- (2014) Jennifer A. Perry et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Recurrent Somatic Structural Variations Contribute to Tumorigenesis in Pediatric Osteosarcoma
- (2014) Xiang Chen et al. Cell Reports
- Preclinical validation of Aurora kinases-targeting drugs in osteosarcoma
- (2013) E Tavanti et al. BRITISH JOURNAL OF CANCER
- Ganglioside GD2 as a therapeutic target for antibody-mediated therapy in patients with osteosarcoma
- (2013) Michael Roth et al. CANCER
- Natural killer cell therapy and aerosol interleukin-2 for the treatment of osteosarcoma lung metastasis
- (2013) Sergei R. Guma et al. PEDIATRIC BLOOD & CANCER
- Mifamurtide in metastatic and recurrent osteosarcoma: A patient access study with pharmacokinetic, pharmacodynamic, and safety assessments
- (2013) P.M. Anderson et al. PEDIATRIC BLOOD & CANCER
- Wee1 Inhibition by MK-1775 Leads to Tumor Inhibition and Enhances Efficacy of Gemcitabine in Human Sarcomas
- (2013) Jenny M. Kreahling et al. PLoS One
- B7-H3 is Overexpressed in Patients Suffering Osteosarcoma and Associated with Tumor Aggressiveness and Metastasis
- (2013) Ling Wang et al. PLoS One
- Phase II Trial of Trastuzumab in Combination With Cytotoxic Chemotherapy for Treatment of Metastatic Osteosarcoma With Human Epidermal Growth Factor Receptor 2 Overexpression: A Report From the Children's Oncology Group
- (2012) David Ebb et al. JOURNAL OF CLINICAL ONCOLOGY
- Neoadjuvant Chemotherapy With Methotrexate, Cisplatin, and Doxorubicin With or Without Ifosfamide in Nonmetastatic Osteosarcoma of the Extremity: An Italian Sarcoma Group Trial ISG/OS-1
- (2012) Stefano Ferrari et al. JOURNAL OF CLINICAL ONCOLOGY
- Osteosarcoma in Sprague-Dawley rats after long-term treatment with teriparatide (human parathyroid hormone (1-34))
- (2012) Atsushi Watanabe et al. JOURNAL OF TOXICOLOGICAL SCIENCES
- Initial testing (stage 1) of the cyclin dependent kinase inhibitor SCH 727965 (dinaciclib) by the pediatric preclinical testing program
- (2012) Richard Gorlick et al. PEDIATRIC BLOOD & CANCER
- Survival from high-grade localised extremity osteosarcoma: combined results and prognostic factors from three European Osteosarcoma Intergroup randomised controlled trials
- (2011) J. S. Whelan et al. ANNALS OF ONCOLOGY
- A phase II trial of sorafenib in relapsed and unresectable high-grade osteosarcoma after failure of standard multimodal therapy: an Italian Sarcoma Group study
- (2011) G. Grignani et al. ANNALS OF ONCOLOGY
- Synthesis of biotinylated muramyl tripeptides with NOD2-stimulating activity
- (2011) Nicolas Gisch et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- WEE1 inhibition sensitizes osteosarcoma to radiotherapy
- (2011) Jantine PosthumaDeBoer et al. BMC CANCER
- Effect of the histone deacetylase inhibitor SNDX-275 on Fas signaling in osteosarcoma cells and the feasibility of its topical application for the treatment of osteosarcoma lung metastases
- (2011) Nadezhda V. Koshkina et al. CANCER
- Cell surface receptor expression patterns in osteosarcoma
- (2011) Sheref E. Hassan et al. CANCER
- Frontline treatment of localized osteosarcoma without methotrexate
- (2011) Najat C. Daw et al. CANCER
- Massive Genomic Rearrangement Acquired in a Single Catastrophic Event during Cancer Development
- (2011) Philip J. Stephens et al. CELL
- Chemotherapeutic adjuvant treatment for osteosarcoma: Where do we stand?
- (2011) Jakob K. Anninga et al. EUROPEAN JOURNAL OF CANCER
- Characterization of canine osteosarcoma by array comparative genomic hybridization and RT-qPCR: Signatures of genomic imbalance in canine osteosarcoma parallel the human counterpart
- (2011) Andrea Y. Angstadt et al. GENES CHROMOSOMES & CANCER
- The Cyclin-Dependent Kinase Inhibitor SCH 727965 (Dinacliclib) Induces the Apoptosis of Osteosarcoma Cells
- (2011) W. Fu et al. MOLECULAR CANCER THERAPEUTICS
- CD73: A Novel Target for Cancer Immunotherapy
- (2010) B. Zhang CANCER RESEARCH
- Inhaled Granulocyte-Macrophage Colony Stimulating Factor for First Pulmonary Recurrence of Osteosarcoma: Effects on Disease-Free Survival and Immunomodulation. A Report From the Children's Oncology Group
- (2010) C. A. S. Arndt et al. CLINICAL CANCER RESEARCH
- Medulloblastoma Comprises Four Distinct Molecular Variants
- (2010) Paul A. Northcott et al. JOURNAL OF CLINICAL ONCOLOGY
- Addition of muramyl tripeptide to chemotherapy for patients with newly diagnosed metastatic osteosarcoma
- (2009) Alexander J. Chou et al. CANCER
- Osteosarcoma incidence and survival rates from 1973 to 2004
- (2009) Lisa Mirabello et al. CANCER
- Phase II Multicenter Trial of Imatinib in 10 Histologic Subtypes of Sarcoma Using a Bayesian Hierarchical Statistical Model
- (2009) Rashmi Chugh et al. JOURNAL OF CLINICAL ONCOLOGY
- High grade osteosarcoma of the extremities metastatic to the lung: Long-term results in 323 patients treated combining surgery and chemotherapy, 1985–2005
- (2009) Antonio Briccoli et al. SURGICAL ONCOLOGY-OXFORD
- The Comparative Oncology Trials Consortium: Using Spontaneously Occurring Cancers in Dogs to Inform the Cancer Drug Development Pathway
- (2009) Ira Gordon et al. PLOS MEDICINE
- Platelet-derived growth factor receptor as a prognostic marker and a therapeutic target for imatinib mesylate therapy in osteosarcoma
- (2008) Tadahiko Kubo et al. CANCER
- Conditional mouse osteosarcoma, dependent on p53 loss and potentiated by loss of Rb, mimics the human disease
- (2008) C. R. Walkley et al. GENES & DEVELOPMENT
- Osteosarcoma: The Addition of Muramyl Tripeptide to Chemotherapy Improves Overall Survival—A Report From the Children's Oncology Group
- (2008) Paul A. Meyers et al. JOURNAL OF CLINICAL ONCOLOGY
- Metastatic osteosarcoma induced by inactivation of Rb and p53 in the osteoblast lineage
- (2008) S. D. Berman et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Initial testing of dasatinib by the pediatric preclinical testing program
- (2007) E. Anders Kolb et al. PEDIATRIC BLOOD & CANCER
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