WEE1 inhibition sensitizes osteosarcoma to radiotherapy

Non-randomized therapy trial to determine the safety and efficacy of heavy ion radiotherapy in patients with non-resectable osteosarcoma

(2010) Claudia Blattmann et al.   BMC CANCER

In Silico Analysis of Kinase Expression Identifies WEE1 as a Gatekeeper against Mitotic Catastrophe in Glioblastoma

(2010) Shahryar E. Mir et al.   CANCER CELL

Swe1Wee1-Dependent Tyrosine Phosphorylation of Hsp90 Regulates Distinct Facets of Chaperone Function

(2010) Mehdi Mollapour et al.   MOLECULAR CELL

Gauchos and ochos: a Wee1-Cdk tango regulating mitotic entry

(2010) Greg H Enders   Cell Division

Tyrosines in the Kinesin-5 Head Domain Are Necessary for Phosphorylation by Wee1 and for Mitotic Spindle Integrity

(2009) Kristin Garcia et al.   CURRENT BIOLOGY

Long-term outcome after polychemotherapy and intensive local radiation therapy of high-grade osteosarcoma

(2009) Patrick Hundsdoerfer et al.   EUROPEAN JOURNAL OF CANCER

The combined status of ATM and p53 link tumor development with therapeutic response

(2009) H. Jiang et al.   GENES & DEVELOPMENT

Small-molecule inhibition of Wee1 kinase by MK-1775 selectively sensitizes p53-deficient tumor cells to DNA-damaging agents

(2009) H. Hirai et al.   MOLECULAR CANCER THERAPEUTICS

Bone Tumors in Adolescents and Young Adults

(2008) Stefan S. Bielack et al.   CURRENT TREATMENT OPTIONS IN ONCOLOGY

Novel bone cancer drugs: investigational agents and control paradigms for primary bone sarcomas (Ewing's sarcoma and osteosarcoma)

(2008) Pete Anderson et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Combination Short-Course Preoperative Irradiation, Surgical Resection, and Reduced-Field High-Dose Postoperative Irradiation in the Treatment of Tumors Involving the Bone

(2008) Timothy D. Wagner et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

Multimodality treatment of osteosarcoma: Radiation in a high-risk cohort

(2008) Anita Mahajan et al.   PEDIATRIC BLOOD & CANCER