Wittig reagents for chemoselective sulfenic acid ligation enables global site stoichiometry analysis and redox-controlled mitochondrial targeting

Reactive oxygen species (ROS) as pleiotropic physiological signalling agents

(2020) Helmut Sies et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Analysis of human acetylation stoichiometry defines mechanistic constraints on protein regulation

(2019) Bogi Karbech Hansen et al.   Nature Communications

Activity-Based Sensing for Site-Specific Proteomic Analysis of Cysteine Oxidation

(2019) Yunlong Shi et al.   ACCOUNTS OF CHEMICAL RESEARCH

Global redox proteome and phosphoproteome analysis reveals redox switch in Akt

(2019) Zhiduan Su et al.   Nature Communications

Reactive Oxygen Species in Metabolic and Inflammatory Signaling

(2018) Steven J. Forrester et al.   CIRCULATION RESEARCH

Mitochondrial DNA Is a Pro-Inflammatory Damage-Associated Molecular Pattern Released During Active IBD

(2018) Ray K Boyapati et al.   INFLAMMATORY BOWEL DISEASES

Transient Sulfenic Acids in the Synthesis of Biologically Relevant Products

(2018) Anna Barattucci et al.   MOLECULES

OUP accepted manuscript

(2018)   NUCLEIC ACIDS RESEARCH

The Future of Bioorthogonal Chemistry

(2018) Neal K. Devaraj   ACS Central Science

Comprehensive identification of peptides in tandem mass spectra using an efficient open search engine

(2018) Hao Chi et al.   NATURE BIOTECHNOLOGY

Diverse Redoxome Reactivity Profiles of Carbon Nucleophiles

(2017) Vinayak Gupta et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Systematic and Quantitative Assessment of Hydrogen Peroxide Reactivity With Cysteines Across Human Proteomes

(2017) Ling Fu et al.   MOLECULAR & CELLULAR PROTEOMICS

Chemoproteomics Reveals Chemical Diversity and Dynamics of 4-Oxo-2-nonenal Modifications in Cells

(2017) Rui Sun et al.   MOLECULAR & CELLULAR PROTEOMICS

S-nitrosylation of UCHL1 induces its structural instability and promotes α-synuclein aggregation

(2017) Roshan Kumar et al.   Scientific Reports

Rational design of reversible and irreversible cysteine sulfenic acid-targeted linear C-nucleophiles

(2016) Vinayak Gupta et al.   CHEMICAL COMMUNICATIONS

Peroxiredoxin 6 homodimerization and heterodimerization with glutathione S-transferase pi are required for its peroxidase but not phospholipase A2 activity

(2016) Suiping Zhou et al.   FREE RADICAL BIOLOGY AND MEDICINE

UniProt: the universal protein knowledgebase

(2016)   NUCLEIC ACIDS RESEARCH

Profiling the reactivity of cyclic C-nucleophiles towards electrophilic sulfur in cysteine sulfenic acid

(2016) Vinayak Gupta et al.   Chemical Science

Mitochondrial dysfunction and oxidative stress in aging and cancer

(2016) Anna V. Kudryavtseva et al.   Oncotarget

Mitochondrial diseases

(2016) Gráinne S. Gorman et al.   Nature Reviews Disease Primers

Cysteine-mediated redox signalling in the mitochondria

(2015) D. W. Bak et al.   Molecular BioSystems

Global, in situ, site-specific analysis of protein S-sulfenylation

(2015) Jing Yang et al.   Nature Protocols

Light-Mediated Sulfenic Acid Generation from Photocaged Cysteine Sulfoxide

(2015) Jia Pan et al.   ORGANIC LETTERS

Redox control of protein degradation

(2015) Marta Pajares et al.   Redox Biology

Cellular mechanisms and physiological consequences of redox-dependent signalling

(2014) Kira M. Holmström et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Site-specific mapping and quantification of protein S-sulphenylation in cells

(2014) Jing Yang et al.   Nature Communications

Sulfenic acid chemistry, detection and cellular lifetime

(2013) Vinayak Gupta et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Cysteine-Mediated Redox Signaling: Chemistry, Biology, and Tools for Discovery

(2013) Candice E. Paulsen et al.   CHEMICAL REVIEWS

Global Proteomic Assessment of the Classical Protein-Tyrosine Phosphatome and “Redoxome”

(2011) Robert Karisch et al.   CELL

A large-scale method to measure absolute protein phosphorylation stoichiometries

(2011) Ronghu Wu et al.   NATURE METHODS

Mining the Thiol Proteome for Sulfenic Acid Modifications Reveals New Targets for Oxidation in Cells

(2009) Stephen E. Leonard et al.   ACS Chemical Biology

Bioorthogonal Chemistry: Fishing for Selectivity in a Sea of Functionality

(2009) Ellen M. Sletten et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Sensors and regulators of intracellular pH

(2009) Joseph R. Casey et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Membrane-associated farnesylated UCH-L1 promotes  -synuclein neurotoxicity and is a therapeutic target for Parkinson's disease

(2009) Z. Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Thioredoxins and glutaredoxins as facilitators of protein folding

(2008) Carsten Berndt et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Reconciling the chemistry and biology of reactive oxygen species

(2008) Christine C Winterbourn   Nature Chemical Biology