ALKBH7-mediated demethylation regulates mitochondrial polycistronic RNA processing

N6-methyladenosine of chromosome-associated regulatory RNA regulates chromatin state and transcription

(2020) Jun Liu et al.   SCIENCE

N6-Deoxyadenosine Methylation in Mammalian Mitochondrial DNA

(2020) Ziyang Hao et al.   MOLECULAR CELL

Targeting DGAT1 Ameliorates Glioblastoma by Increasing Fat Catabolism and Oxidative Stress

(2020) Xiang Cheng et al.   Cell Metabolism

Transcription, Processing, and Decay of Mitochondrial RNA in Health and Disease

(2019) Arianna Barchiesi et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Metabolic role of fatty acid binding protein 7 in mediating triple negative breast cancer cell death via PPAR-alpha signalling

(2019) Soke Chee Kwong et al.   JOURNAL OF LIPID RESEARCH

Evolution of a reverse transcriptase to map N1-methyladenosine in human messenger RNA

(2019) Huiqing Zhou et al.   NATURE METHODS

Mitochondrial Gene Expression and Beyond—Novel Aspects of Cellular Physiology

(2019) Anna V. Kotrys et al.   Cells

R-2HG Exhibits Anti-tumor Activity by Targeting FTO/m 6 A/MYC/CEBPA Signaling

(2018) Rui Su et al.   CELL

PKR Senses Nuclear and Mitochondrial Signals by Interacting with Endogenous Double-Stranded RNAs

(2018) Yoosik Kim et al.   MOLECULAR CELL

Mitochondrial double-stranded RNA triggers antiviral signalling in humans

(2018) Ashish Dhir et al.   NATURE

TRMT1-Catalyzed tRNA Modifications Are Required for Redox Homeostasis To Ensure Proper Cellular Proliferation and Oxidative Stress Survival

(2017) Joshua M. Dewe et al.   MOLECULAR AND CELLULAR BIOLOGY

ALKBH7 drives a tissue and sex-specific necrotic cell death response following alkylation-induced damage

(2017) Jennifer J Jordan et al.   Cell Death & Disease

The Biochemistry and Physiology of Mitochondrial Fatty Acid β-Oxidation and Its Genetic Disorders

(2016) Sander M. Houten et al.   Annual Review of Physiology

Combined defects in oxidative phosphorylation and fatty acid  -oxidation in mitochondrial disease

(2016) A. Nsiah-Sefaa et al.   BIOSCIENCE REPORTS

ALKBH1-Mediated tRNA Demethylation Regulates Translation

(2016) Fange Liu et al.   CELL

Transcriptome-wide interrogation of RNA secondary structure in living cells with icSHAPE

(2016) Ryan A Flynn et al.   Nature Protocols

Post-transcriptional gene regulation by mRNA modifications

(2016) Boxuan Simen Zhao et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Death-associated Protein 3 Regulates Mitochondrial-encoded Protein Synthesis and Mitochondrial Dynamics

(2015) Lin Xiao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural imprints in vivo decode RNA regulatory mechanisms

(2015) Robert C. Spitale et al.   NATURE

Efficient and quantitative high-throughput tRNA sequencing

(2015) Guanqun Zheng et al.   NATURE METHODS

ARM-seq: AlkB-facilitated RNA methylation sequencing reveals a complex landscape of modified tRNA fragments

(2015) Aaron E Cozen et al.   NATURE METHODS

The Atomic Resolution Structure of Human AlkB Homolog 7 (ALKBH7), a Key Protein for Programmed Necrosis and Fat Metabolism

(2014) Guoqiang Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A complete landscape of post-transcriptional modifications in mammalian mitochondrial tRNAs

(2014) T. Suzuki et al.   NUCLEIC ACIDS RESEARCH

Human ALKBH7 is required for alkylation and oxidation-induced programmed necrosis

(2013) D. Fu et al.   GENES & DEVELOPMENT

Deletion of mouse Alkbh7 leads to obesity

(2013) A. Solberg et al.   Journal of Molecular Cell Biology

ALKBH4-dependent demethylation of actin regulates actomyosin dynamics

(2013) Ming-Ming Li et al.   Nature Communications

ALKBH5 Is a Mammalian RNA Demethylase that Impacts RNA Metabolism and Mouse Fertility

(2012) Guanqun Zheng et al.   MOLECULAR CELL

Of P and Z: Mitochondrial tRNA processing enzymes

(2011) Walter Rossmanith   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

N6-Methyladenosine in nuclear RNA is a major substrate of the obesity-associated FTO

(2011) Guifang Jia et al.   Nature Chemical Biology

Yeast mitochondrial RNase P, RNase Z and the RNA degradosome are part of a stable supercomplex

(2011) Rachid Daoud et al.   NUCLEIC ACIDS RESEARCH

Mice Lacking Alkbh1 Display Sex-Ratio Distortion and Unilateral Eye Defects

(2010) Line M. Nordstrand et al.   PLoS One

Crystal structures of DNA/RNA repair enzymes AlkB and ABH2 bound to dsDNA

(2008) Cai-Guang Yang et al.   NATURE