pH/ROS dual-sensitive and chondroitin sulfate wrapped poly (β-amino ester)-SA-PAPE copolymer nanoparticles for macrophage-targeted oral therapy for ulcerative colitis

Delivery of triptolide with reduction-sensitive polymer nanoparticles for liver cancer therapy on patient-derived xenografts models

(2020) Mengxue He et al.   CHINESE CHEMICAL LETTERS

Curcumin nanocrystal/pH-responsive polyelectrolyte multilayer core-shell nanoparticles for inflammation-targeted alleviation of ulcerative colitis

(2020) Murtada A. Oshi et al.   BIOMACROMOLECULES

Photodynamic PEG-coated ROS-sensitive prodrug nanoassemblies for core-shell synergistic chemo-photodynamic therapy

(2019) Bingjun Sun et al.   Acta Biomaterialia

Self-facilitated ROS-responsive nanoassembly of heterotypic dimer for synergistic chemo-photodynamic therapy

(2019) Cong Luo et al.   JOURNAL OF CONTROLLED RELEASE

Multi-bioresponsive silk fibroin-based nanoparticles with on-demand cytoplasmic drug release capacity for CD44-targeted alleviation of ulcerative colitis

(2019) Shuangquan Gou et al.   BIOMATERIALS

Oral administration of chondroitin sulfate-functionalized nanoparticles for colonic macrophage-targeted drug delivery

(2019) Xueqing Zhang et al.   CARBOHYDRATE POLYMERS

Targeted pH-responsive polyion complex micelle for controlled intracellular drug delivery

(2019) Pan Zheng et al.   CHINESE CHEMICAL LETTERS

A self-assembled, ROS-responsive Janus-prodrug for targeted therapy of inflammatory bowel disease

(2019) Shanshan Li et al.   JOURNAL OF CONTROLLED RELEASE

Targeted Delivery of Doxorubicin via CD147-Mediated ROS/pH Dual-Sensitive Nanomicelles for the Efficient Therapy of Hepatocellular Carcinoma

(2018) Chenxi Qu et al.   AAPS Journal

Colon-targeted dexamethasone microcrystals with pH-sensitive chitosan/alginate/Eudragit S multilayers for the treatment of inflammatory bowel disease

(2018) Murtada A. Oshi et al.   CARBOHYDRATE POLYMERS

Biodistribution and targeting potential assessment of mucoadhesive chitosan nanoparticles designed for ulcerative colitis via scintigraphy

(2018) Pooja Mongia Raj et al.   RSC Advances

Delivery of tacrolimus with cationic lipid-assisted nanoparticles for ulcerative colitis therapy

(2018) Ji-Long Wang et al.   Biomaterials Science

Curcumin as a therapeutic agent for blocking NF-κB activation in ulcerative colitis

(2018) Yiqing Wang et al.   IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY

TNFα gene silencing mediated by orally targeted nanoparticles combined with interleukin-22 for synergistic combination therapy of ulcerative colitis

(2018) Bo Xiao et al.   JOURNAL OF CONTROLLED RELEASE

Green Fabrication of Ovalbumin Nanoparticles as Natural Polyphenol Carriers for Ulcerative Colitis Therapy

(2018) Shuangquan Gou et al.   ACS Sustainable Chemistry & Engineering

pH and Reactive Oxygen Species‐Sequential Responsive Nano‐in‐Micro Composite for Targeted Therapy of Inflammatory Bowel Disease

(2018) Serena Bertoni et al.   ADVANCED FUNCTIONAL MATERIALS

Oral administration of colitis tissue-accumulating porous nanoparticles for ulcerative colitis therapy

(2018) Qiubing Chen et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Worldwide incidence and prevalence of inflammatory bowel disease in the 21st century: a systematic review of population-based studies

(2017) Siew C Ng et al.   LANCET

Oxidation-Responsive Aliphatic Polycarbonates from N -Substituted Eight-Membered Cyclic Carbonate: Synthesis and Degradation Study

(2017) Fang-Yi Qiu et al.   MACROMOLECULAR RAPID COMMUNICATIONS

Self-assembled nanoparticles based on a carboxymethylcellulose–ursolic acid conjugate for anticancer combination therapy

(2017) Yan-xue Liu et al.   RSC Advances

Multiple Functions of D-α-Tocopherol Polyethylene Glycol 1000 Succinate (TPGS) as Curcumin Nanoparticle Stabilizer: In Vivo Kinetic Profile and Anti-Ulcerative Colitis Analysis in Animal Model

(2017) Heni Rachmawati et al.   Pharmaceutics

Curcumin as a therapeutic agent in the chemoprevention of inflammatory bowel disease

(2016) Remya Sreedhar et al.   DRUG DISCOVERY TODAY

Inflammation related responses of intestinal cells to plum and cabbage digesta with differential carotenoid and polyphenol profiles following simulated gastrointestinal digestion

(2016) Anouk Kaulmann et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Effect of piperine on inhibition of FFA induced TLR4 mediated inflammation and amelioration of acetic acid induced ulcerative colitis in mice

(2015) Rohit A. Gupta et al.   JOURNAL OF ETHNOPHARMACOLOGY

Hydrogel drug delivery for inflammatory bowel disease

(2015) Megan Cully   NATURE REVIEWS DRUG DISCOVERY

Hyaluronic Acid-Decorated Graphene Oxide Nanohybrids as Nanocarriers for Targeted and pH-Responsive Anticancer Drug Delivery

(2014) Erqun Song et al.   ACS Applied Materials & Interfaces

Treatment of IBD: Where We Are and Where We Are Going

(2014) Charles N Bernstein   AMERICAN JOURNAL OF GASTROENTEROLOGY

Nanoparticles With Surface Antibody Against CD98 and Carrying CD98 Small Interfering RNA Reduce Colitis in Mice

(2014) Bo Xiao et al.   GASTROENTEROLOGY

Self-assembled micelles based on pH-sensitive PAE-g-MPEG-cholesterol block copolymer for anticancer drug delivery

(2014) Lijuan Zhang et al.   International Journal of Nanomedicine

ROS-triggered and regenerating anticancer nanosystem: An effective strategy to subdue tumor's multidrug resistance

(2014) Zhigui Su et al.   JOURNAL OF CONTROLLED RELEASE

Biocompatible Reactive Oxygen Species (ROS)-Responsive Nanoparticles as Superior Drug Delivery Vehicles

(2014) Dinglin Zhang et al.   Advanced Healthcare Materials

Induction with NCB-02 (curcumin) enema for mild-to-moderate distal ulcerative colitis — A randomized, placebo-controlled, pilot study

(2013) Vikas Singla et al.   Journal of Crohns & Colitis

Therapeutic potential of curcumin in digestive diseases

(2013) Pietro Dulbecco   WORLD JOURNAL OF GASTROENTEROLOGY

Do different animal models of IBD serve different purposes?

(2012) Matthew B. Grisham   INFLAMMATORY BOWEL DISEASES

Dextran Sodium Sulphate Colitis Mouse Model: Traps and Tricks

(2012) Martina Perše et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Nutraceuticals as new treatment approaches for oral cancer – I: Curcumin

(2012) Ayelet Zlotogorski et al.   ORAL ONCOLOGY

Curcumin, an active component of turmeric in the prevention and treatment of ulcerative colitis: preclinical and clinical observations

(2012) Manjeshwar Shrinath Baliga et al.   Food & Function

Intestinal homeostasis and its breakdown in inflammatory bowel disease

(2011) Kevin J. Maloy et al.   NATURE

Ulcerative Colitis

(2011) Silvio Danese et al.   NEW ENGLAND JOURNAL OF MEDICINE

Nitric oxide-releasing aspirin but not conventional aspirin improves healing of experimental colitis

(2011) Malgorzata Zwolinska-Wcislo   WORLD JOURNAL OF GASTROENTEROLOGY

Prophylactic role of curcumin in dextran sulfate sodium (DSS)-induced ulcerative colitis murine model

(2009) Hossam M.M. Arafa et al.   FOOD AND CHEMICAL TOXICOLOGY

Drug-Loaded Nanoparticles Targeted to the Colon With Polysaccharide Hydrogel Reduce Colitis in a Mouse Model

(2009) Hamed Laroui et al.   GASTROENTEROLOGY