Saffron and Its Major Ingredients’ Effect on Colon Cancer Cells with Mismatch Repair Deficiency and Microsatellite Instability

Epigenetics of colorectal cancer: biomarker and therapeutic potential

(2020) Gerhard Jung et al.   Nature Reviews Gastroenterology & Hepatology

Saffron Crudes and Compounds Restrict MACC1-Dependent Cell Proliferation and Migration of Colorectal Cancer Cells

(2020) Nazli Güllü et al.   Cells

Colorectal Cancer and Nutrition

(2019) Kannan Thanikachalam et al.   Nutrients

Crocin inhibits the migration, invasion, and epithelial-mesenchymal transition of gastric cancer cells via miR-320/KLF5/HIF-1α signaling

(2019) Ying Zhou et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Saffron: The Golden Spice with Therapeutic Properties on Digestive Diseases

(2019) Hassan Ashktorab et al.   Nutrients

Global burden of colorectal cancer: emerging trends, risk factors and prevention strategies

(2019) NaNa Keum et al.   Nature Reviews Gastroenterology & Hepatology

Crocin has pharmacological effects against the pathological behavior of colon cancer cells by interacting with the STAT3 signaling pathway

(2019) Jun Wang et al.   Experimental and Therapeutic Medicine

Crocin promotes apoptosis of human skin cancer cells by inhibiting the JAK/STAT pathway

(2018) Gongfeng Wang et al.   Experimental and Therapeutic Medicine

Safranal induces DNA double-strand breakage and ER-stress-mediated cell death in hepatocellular carcinoma cells

(2018) Ala’a Al-Hrout et al.   Scientific Reports

Racial Disparity in Gastrointestinal Cancer Risk

(2017) Hassan Ashktorab et al.   GASTROENTEROLOGY

Evaluation of the Cytotoxic Activity of Crocin and Safranal, Constituents of Saffron, in Oral Squamous Cell Carcinoma (KB Cell Line)

(2017) Raheleh Jabini et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

Distinctive DNA mismatch repair and APC rare variants in African Americans with colorectal neoplasia

(2017) Hassan Ashktorab et al.   Oncotarget

Saffron-Based Crocin Prevents Early Lesions of Liver Cancer: In vivo, In vitro and Network Analyses

(2016) Amr Amin et al.   Recent Patents on Anti-Cancer Drug Discovery

Defective Autophagosome Formation in p53-Null Colorectal Cancer Reinforces Crocin-Induced Apoptosis

(2015) Amr Amin et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

MSH3 expression does not influence the sensitivity of colon cancer HCT116 cell line to oxaliplatin and poly(ADP-ribose) polymerase (PARP) inhibitor as monotherapy or in combination

(2013) Lucio Tentori et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Crocin Triggers the Apoptosis Through Increasing the Bax/Bcl-2 Ratio and Caspase Activation in Human Gastric Adenocarcinoma, AGS, Cells

(2013) Reyhane Hoshyar et al.   DNA AND CELL BIOLOGY

Assessment of Cytotoxic Properties of Safranal and Nanoliposomal Safranal in Various Cancer Cell Lines

(2013) Bizhan Malaekeh-Nikouei et al.   PHYTOTHERAPY RESEARCH

Synergistic apoptotic effect of crocin and cisplatin on osteosarcoma cells via caspase induced apoptosis

(2013) Xiucheng Li et al.   TOXICOLOGY LETTERS

The anticancer effect of saffron in two p53 isogenic colorectal cancer cell lines

(2012) Khuloud Bajbouj et al.   BMC Complementary and Alternative Medicine

Doxorubicin promotes transcriptional upregulation of Cdc25B in cancer cells by releasing Sp1 from the promoter

(2012) M Dalvai et al.   ONCOGENE

Correction: Colorectal Cancer Migration and Invasion Initiated by microRNA-106a

(2012) Bo Feng et al.   PLoS One

Targeting PI3K Signaling as a Therapeutic Approach for Colorectal Cancer

(2011) Jing Zhang et al.   GASTROENTEROLOGY

Saffron: A potential candidate for a novel anticancer drug against hepatocellular carcinoma

(2011) Amr Amin et al.   HEPATOLOGY

Role of caspases and Bax protein in saffron-induced apoptosis in MCF-7 cells

(2009) Seyed Hadi Mousavi et al.   FOOD AND CHEMICAL TOXICOLOGY

Study of cytotoxic and apoptogenic properties of saffron extract in human cancer cell lines

(2008) Jalil Tavakkol-Afshari et al.   FOOD AND CHEMICAL TOXICOLOGY