Extracellular vesicles derived from inflammatory-educated stem cells reverse brain inflammation—implication of miRNAs
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Title
Extracellular vesicles derived from inflammatory-educated stem cells reverse brain inflammation—implication of miRNAs
Authors
Keywords
mesenchymal stem cells, MSCs, extracellular vesicles, EVs, MSC priming, Alzheimer’s disease, AD, microglia, amyloid beta oligomers, AβOs, lipopolysaccharide, LPS, miRNAs
Journal
MOLECULAR THERAPY
Volume -, Issue -, Pages -
Publisher
Elsevier BV
Online
2021-08-08
DOI
10.1016/j.ymthe.2021.08.008
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Note: Only part of the references are listed.- MCP-1 Priming Enhanced the Therapeutic Effects of Mesenchymal Stromal Cells on Contact Hypersensitivity by Activating the COX2-PGE2/STAT3 Pathway
- (2020) Qiuli Liu et al. STEM CELLS AND DEVELOPMENT
- Bone marrow-derived mesenchymal stem cells improve cognitive impairment in an Alzheimer’s disease model by increasing the expression of microRNA-146a in hippocampus
- (2020) Masako Nakano et al. Scientific Reports
- Exosomes derived from umbilical cord mesenchymal stem cells reduce microglia-mediated neuroinflammation in perinatal brain injury
- (2019) Gierin Thomi et al. Stem Cell Research & Therapy
- Exploiting microglial and peripheral immune cell crosstalk to treat Alzheimer’s disease
- (2019) Dawling A. Dionisio-Santos et al. Journal of Neuroinflammation
- Preconditioning in an Inflammatory Milieu Augments the Immunotherapeutic Function of Mesenchymal Stromal Cells
- (2019) Rodriguez et al. Cells
- Noradrenergic dysfunction accelerates LPS-elicited inflammation-related ascending sequential neurodegeneration and deficits in non-motor/motor functions
- (2019) Sheng Song et al. BRAIN BEHAVIOR AND IMMUNITY
- Neuroinflammation induced by lipopolysaccharide causes cognitive impairment in mice
- (2019) Jiayi Zhao et al. Scientific Reports
- Intranasal Delivery of Mesenchymal Stem Cell Derived Exosomes Loaded with Phosphatase and Tensin Homolog siRNA Repairs Complete Spinal Cord Injury
- (2019) Shaowei Guo et al. ACS Nano
- Porcine Milk Exosome MiRNAs Attenuate LPS-Induced Apoptosis through Inhibiting TLR4/NF-κB and p53 Pathways in Intestinal Epithelial Cells
- (2019) Mei-Ying Xie et al. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
- Intranasally Administered Exosomes from Umbilical Cord Stem Cells Have Preventive Neuroprotective Effects and Contribute to Functional Recovery after Perinatal Brain Injury
- (2019) Thomi et al. Cells
- Pioglitazone treatment prior to transplantation improves the efficacy of human mesenchymal stem cells after traumatic brain injury in rats
- (2019) Mahasweta Das et al. Scientific Reports
- Isoalantolactone suppresses LPS-induced inflammation by inhibiting TRAF6 ubiquitination and alleviates acute lung injury
- (2018) Yun-he Ding et al. ACTA PHARMACOLOGICA SINICA
- Alzheimer’s Disease, Oligomers, and Inflammation
- (2018) Gianluigi Forloni et al. JOURNAL OF ALZHEIMERS DISEASE
- JNK1 inhibition by Licochalcone A leads to neuronal protection against excitotoxic insults derived of kainic acid
- (2018) Oriol Busquets et al. NEUROPHARMACOLOGY
- Optimizing exosomal RNA isolation for RNA-Seq analyses of archival sera specimens
- (2018) Emily N. Prendergast et al. PLoS One
- Human Mesenchymal Stromal Cell-Derived Extracellular Vesicles Modify Microglial Response and Improve Clinical Outcomes in Experimental Spinal Cord Injury
- (2018) Katherine A. Ruppert et al. Scientific Reports
- Lipopolysaccharide Associates with Amyloid Plaques, Neurons and Oligodendrocytes in Alzheimer’s Disease Brain: A Review
- (2018) Xinhua Zhan et al. Frontiers in Aging Neuroscience
- Inflammasome signalling in brain function and neurodegenerative disease
- (2018) Michael T. Heneka et al. NATURE REVIEWS NEUROSCIENCE
- TLR4 signaling pathway mediates the LPS/ischemia-induced expression of monocytechemotactic protein-induced protein 1 in microglia
- (2018) Shumin Chen et al. NEUROSCIENCE LETTERS
- Pro inflammatory stimuli enhance the immunosuppressive functions of adipose mesenchymal stem cells-derived exosomes
- (2018) Rossana Domenis et al. Scientific Reports
- Artemisinin B Improves Learning and Memory Impairment in AD Dementia Mice by Suppressing Neuroinflammation
- (2018) Weijie Qiang et al. NEUROSCIENCE
- Role of Microglia TLRs in Neurodegeneration
- (2018) Bernd L. Fiebich et al. Frontiers in Cellular Neuroscience
- A presumed antagonistic LPS identifies distinct functional organization of TLR4 in mouse microglia
- (2017) Christin Döring et al. GLIA
- The extracellular signal-regulated kinase 1/2 pathway in neurological diseases: A potential therapeutic target (Review)
- (2017) Jing Sun et al. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
- Microglia in Alzheimer’s disease
- (2017) Heela Sarlus et al. JOURNAL OF CLINICAL INVESTIGATION
- Neuroinflammatory responses in Alzheimer’s disease
- (2017) Cira Dansokho et al. JOURNAL OF NEURAL TRANSMISSION
- Modulation of neuroinflammation and pathology in the 5XFAD mouse model of Alzheimer's disease using a biased and selective beta-1 adrenergic receptor partial agonist
- (2017) Pooneh Memar Ardestani et al. NEUROPHARMACOLOGY
- Lipopolysaccharide enters the rat brain by a lipoprotein-mediated transport mechanism in physiological conditions
- (2017) Alejandra Vargas-Caraveo et al. Scientific Reports
- Exosomes as therapeutic drug carriers and delivery vehicles across biological membranes: current perspectives and future challenges
- (2016) Dinh Ha et al. Acta Pharmaceutica Sinica B
- Dysregulation of microRNA-219 promotes neurodegeneration through post-transcriptional regulation of tau
- (2015) Ismael Santa-Maria et al. JOURNAL OF CLINICAL INVESTIGATION
- LPS-preconditioned mesenchymal stromal cells modify macrophage polarization for resolution of chronic inflammation via exosome-shuttled let-7b
- (2015) Dongdong Ti et al. Journal of Translational Medicine
- Evaluation of the Role of JNK1 in the Hippocampus in an Experimental Model of Familial Alzheimer’s Disease
- (2015) Dmitry Petrov et al. MOLECULAR NEUROBIOLOGY
- Extracellular Vesicles Improve Post-Stroke Neuroregeneration and Prevent Postischemic Immunosuppression
- (2015) Thorsten R. Doeppner et al. Stem Cells Translational Medicine
- Pycnogenol Attenuates the Release of Proinflammatory Cytokines and Expression of Perilipin 2 in Lipopolysaccharide-Stimulated Microglia in Part via Inhibition of NF-κB and AP-1 Activation
- (2015) Bin Fan et al. PLoS One
- Neuroinflammation and M2 microglia: the good, the bad, and the inflamed
- (2014) Jonathan D Cherry et al. Journal of Neuroinflammation
- Epigenetic Modification of Spinal miR-219 Expression Regulates Chronic Inflammation Pain by Targeting CaMKII
- (2014) Z. Pan et al. JOURNAL OF NEUROSCIENCE
- Sorting it out: Regulation of exosome loading
- (2014) Carolina Villarroya-Beltri et al. SEMINARS IN CANCER BIOLOGY
- Exosomes from marrow stromal cells expressing miR-146b inhibit glioma growth
- (2013) Mark Katakowski et al. CANCER LETTERS
- Toll-like receptor 4 mediates microglial activation and production of inflammatory mediators in neonatal rat brain following hypoxia: role of TLR4 in hypoxic microglia
- (2013) Linli Yao et al. Journal of Neuroinflammation
- Physiology: Inflammation links ageing to the brain
- (2013) Dana Gabuzda et al. NATURE
- Mesenchymal Stem Cells from Human Umbilical Cord Express Preferentially Secreted Factors Related to Neuroprotection, Neurogenesis, and Angiogenesis
- (2013) Jui-Yu Hsieh et al. PLoS One
- Mesenchymal stem cell: An efficient mass producer of exosomes for drug delivery
- (2012) Ronne Wee Yeh Yeo et al. ADVANCED DRUG DELIVERY REVIEWS
- Exosome-Mediated Transfer of miR-133b from Multipotent Mesenchymal Stromal Cells to Neural Cells Contributes to Neurite Outgrowth
- (2012) Hongqi Xin et al. STEM CELLS
- Treatment of Brain Inflammatory Diseases by Delivering Exosome Encapsulated Anti-inflammatory Drugs From the Nasal Region to the Brain
- (2011) Xiaoying Zhuang et al. MOLECULAR THERAPY
- Delivery of siRNA to the mouse brain by systemic injection of targeted exosomes
- (2011) Lydia Alvarez-Erviti et al. NATURE BIOTECHNOLOGY
- Analysis of deep sequencing microRNA expression profile from human embryonic stem cells derived mesenchymal stem cells reveals possible role of let-7 microRNA family in downstream targeting of Hepatic Nuclear Factor 4 Alpha
- (2010) Winston Koh et al. BMC GENOMICS
- Inflammatory conditions affect gene expression and function of human adipose tissue-derived mesenchymal stem cells
- (2010) M. J. Crop et al. CLINICAL AND EXPERIMENTAL IMMUNOLOGY
- Microglial activation depends on beta-amyloid conformation: role of the formylpeptide receptor 2
- (2010) Tony Heurtaux et al. JOURNAL OF NEUROCHEMISTRY
- Beta amyloid oligomers and fibrils stimulate differential activation of primary microglia
- (2009) Cindy M Sondag et al. Journal of Neuroinflammation
- Inflammation in Alzheimer's disease: Amyloid-β oligomers trigger innate immunity defence via pattern recognition receptors
- (2009) Antero Salminen et al. PROGRESS IN NEUROBIOLOGY
- Amyloid-β oligomers set fire to inflammasomes and induce Alzheimer's pathology
- (2008) Antero Salminen et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
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