Atypical perineuronal nets in the CA2 region interfere with social memory in a mouse model of social dysfunction

Integrated analysis of miRNA and mRNA expression profiles in the brains of BTBR mice

(2020) Min Wang et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE

Microglial Remodeling of the Extracellular Matrix Promotes Synapse Plasticity

(2020) Phi T. Nguyen et al.   CELL

Circadian Rhythms of Perineuronal Net Composition

(2020) Harry Pantazopoulos et al.   eNeuro

Adult-born neurons in the hippocampus are essential for social memory maintenance

(2020) Elise C Cope et al.   eNeuro

Adult Neurogenesis, Glia, and the Extracellular Matrix

(2019) Elise C. Cope et al.   Cell Stem Cell

Novel role for mineralocorticoid receptors in control of a neuronal phenotype

(2019) Katharine E. McCann et al.   MOLECULAR PSYCHIATRY

Maturation of PNN and ErbB4 Signaling in Area CA2 during Adolescence Underlies the Emergence of PV Interneuron Plasticity and Social Memory

(2019) Soledad Domínguez et al.   Cell Reports

Inhibiting constitutive neurogenesis compromises long-term social recognition memory

(2018) Ana Raquel Pereira-Caixeta et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Increased Excitability and Reduced Excitatory Synaptic Input Into Fast-Spiking CA2 Interneurons After Enzymatic Attenuation of Extracellular Matrix

(2018) Hussam Hayani et al.   Frontiers in Cellular Neuroscience

Regulation of synaptic plasticity in hippocampal area CA2

(2018) Kelly E Carstens et al.   CURRENT OPINION IN NEUROBIOLOGY

Microglia play an active role in obesity-associated cognitive decline

(2018) Elise C. Cope et al.   JOURNAL OF NEUROSCIENCE

Neuroimaging hippocampal subfields in schizophrenia and bipolar disorder: A systematic review and meta-analysis

(2018) Unn K. Haukvik et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Social brain, social dysfunction and social withdrawal

(2018) Stefano Porcelli et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

The hippocampal sharp wave–ripple in memory retrieval for immediate use and consolidation

(2018) Hannah R. Joo et al.   NATURE REVIEWS NEUROSCIENCE

A hippocampal circuit linking dorsal CA2 to ventral CA1 critical for social memory dynamics

(2018) Torcato Meira et al.   Nature Communications

Disruption of perineuronal nets increases the frequency of sharp wave ripple events

(2017) Zhi Yong Sun et al.   HIPPOCAMPUS

The social hippocampus

(2017) Alison Montagrin et al.   HIPPOCAMPUS

Multi-modal MRI investigation of volumetric and microstructural changes in the hippocampus and its subfields in mild cognitive impairment, Alzheimer's disease, and dementia with Lewy bodies

(2017) Elijah Mak et al.   INTERNATIONAL PSYCHOGERIATRICS

The Efficacy of Emotion Recognition Rehabilitation for People with Alzheimer’s Disease

(2017) J. Antonio García-Casal et al.   JOURNAL OF ALZHEIMERS DISEASE

Genetic Otx2 mis-localization delays critical period plasticity across brain regions

(2017) H H C Lee et al.   MOLECULAR PSYCHIATRY

On the Integration of Space, Time, and Memory

(2017) Howard Eichenbaum   NEURON

The BTBR mouse model of idiopathic autism – Current view on mechanisms

(2017) K.Z. Meyza et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Dynamic microglial modulation of spatial learning and social behavior

(2016) Luisa Torres et al.   BRAIN BEHAVIOR AND IMMUNITY

Casting a Wide Net: Role of Perineuronal Nets in Neural Plasticity

(2016) Barbara A. Sorg et al.   JOURNAL OF NEUROSCIENCE

Perineuronal Nets Suppress Plasticity of Excitatory Synapses on CA2 Pyramidal Neurons

(2016) K. E. Carstens et al.   JOURNAL OF NEUROSCIENCE

Removal of Perineuronal Nets Unlocks Juvenile Plasticity Through Network Mechanisms of Decreased Inhibition and Increased Gamma Activity

(2016) Kristian Kinden Lensjø et al.   JOURNAL OF NEUROSCIENCE

Microglial Polarization and Inflammatory Mediators After Intracerebral Hemorrhage

(2016) Zhen Zhang et al.   MOLECULAR NEUROBIOLOGY

Neurogenesis Inhibition Prevents Enriched Environment to Prolong and Strengthen Social Recognition Memory, But Not to Increase BDNF Expression

(2016) Ana Raquel Pereira-Caixeta et al.   MOLECULAR NEUROBIOLOGY

Targeted activation of the hippocampal CA2 area strongly enhances social memory

(2016) A S Smith et al.   MOLECULAR PSYCHIATRY

Rediscovering area CA2: unique properties and functions

(2016) Serena M. Dudek et al.   NATURE REVIEWS NEUROSCIENCE

A Designer AAV Variant Permits Efficient Retrograde Access to Projection Neurons

(2016) D. Gowanlock R. Tervo et al.   NEURON

Ventral CA1 neurons store social memory

(2016) T. Okuyama et al.   SCIENCE

Chondroitin 6-Sulfation Regulates Perineuronal Net Formation by Controlling the Stability of Aggrecan

(2016) Shinji Miyata et al.   NEURAL PLASTICITY

In Sickness and in Health: Perineuronal Nets and Synaptic Plasticity in Psychiatric Disorders

(2016) Harry Pantazopoulos et al.   NEURAL PLASTICITY

Comparative Gene Expression Analysis of Two Mouse Models of Autism: Transcriptome Profiling of the BTBR and En2−/− Hippocampus

(2016) Giovanni Provenzano et al.   Frontiers in Neuroscience

Novel connection between newborn granule neurons and the hippocampal CA2 field

(2015) María Llorens-Martín et al.   EXPERIMENTAL NEUROLOGY

Perineuronal net digestion with chondroitinase restores memory in mice with tau pathology

(2015) Sujeong Yang et al.   EXPERIMENTAL NEUROLOGY

Conditional Reduction of Adult Born Doublecortin-Positive Neurons Reversibly Impairs Selective Behaviors

(2015) Lillian Garrett et al.   Frontiers in Behavioral Neuroscience

Hippocampal Transcriptomic and Proteomic Alterations in the BTBR Mouse Model of Autism Spectrum Disorder

(2015) Caitlin M. Daimon et al.   Frontiers in Physiology

Lesions to the CA2 region of the hippocampus impair social memory in mice

(2014) Erica L. Stevenson et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Perineuronal nets affect parvalbumin expression in GABAergic neurons of the mouse hippocampus

(2014) J. Yamada et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

The hippocampal CA2 region is essential for social memory

(2014) Frederick L. Hitti et al.   NATURE

Modulation of the proteoglycan receptor PTPσ promotes recovery after spinal cord injury

(2014) Bradley T. Lang et al.   NATURE

Long-Term Memory Deficits are Associated with Elevated Synaptic ERK1/2 Activation and Reversed by mGluR5 Antagonism in an Animal Model of Autism

(2014) Ronald R Seese et al.   NEUROPSYCHOPHARMACOLOGY

Chondroitin sulfate proteoglycans inhibit oligodendrocyte myelination through PTPσ

(2013) James C. Pendleton et al.   EXPERIMENTAL NEUROLOGY

Enriched environment increases neurogenesis and improves social memory persistence in socially isolated adult mice

(2013) Brisa M.M. Monteiro et al.   HIPPOCAMPUS

Distinct physiological and developmental properties of hippocampal CA2 subfield revealed by using anti-Purkinje cell protein 4 (PCP4) immunostaining

(2013) Andrew San Antonio et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Disruption of the perineuronal net in the hippocampus or medial prefrontal cortex impairs fear conditioning

(2013) M. J. Hylin et al.   LEARNING & MEMORY

Astrocytes mediate synapse elimination through MEGF10 and MERTK pathways

(2013) Won-Suk Chung et al.   NATURE

Cell type–specific genetic and optogenetic tools reveal hippocampal CA2 circuits

(2013) Keigo Kohara et al.   NATURE NEUROSCIENCE

Quantitative Trait Loci for Interhemispheric Commissure Development and Social Behaviors in the BTBR T+ tf/J Mouse Model of Autism

(2013) Dorothy M. Jones-Davis et al.   PLoS One

Choroid-Plexus-Derived Otx2 Homeoprotein Constrains Adult Cortical Plasticity

(2013) Julien Spatazza et al.   Cell Reports

Microglial Cell Activation is a Source of Metalloproteinase Generation during Hemorrhagic Transformation

(2012) Gregory J del Zoppo et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Otx2 Binding to Perineuronal Nets Persistently Regulates Plasticity in the Mature Visual Cortex

(2012) M. Beurdeley et al.   JOURNAL OF NEUROSCIENCE

Microglia Sculpt Postnatal Neural Circuits in an Activity and Complement-Dependent Manner

(2012) Dorothy P. Schafer et al.   NEURON

Low sociability in BTBR T+tf/J mice is independent of partner strain

(2012) Mu Yang et al.   PHYSIOLOGY & BEHAVIOR

Vasopressin Inhibits LTP in the CA2 Mouse Hippocampal Area

(2012) Magda Chafai et al.   PLoS One

Cognitive and social cognitive predictors of change in objective versus subjective quality-of-life in rehabilitation for schizophrenia

(2012) Matthew M. Kurtz et al.   PSYCHIATRY RESEARCH

Molecular signals of plasticity at the tetrapartite synapse

(2011) Alexander Dityatev et al.   CURRENT OPINION IN NEUROBIOLOGY

BTBR T+tf/J mice: Autism-relevant behaviors and reduced fractone-associated heparan sulfate

(2011) D. Caroline Blanchard et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Synaptic Pruning by Microglia Is Necessary for Normal Brain Development

(2011) R. C. Paolicelli et al.   SCIENCE

Histopathologic characterization of the BTBR mouse model of autistic-like behavior reveals selective changes in neurodevelopmental proteins and adult hippocampal neurogenesis

(2011) Diane T Stephenson et al.   Molecular Autism

Autism-like behavioral phenotypes in BTBR T+tf/J mice

(2007) H. G. McFarlane et al.   GENES BRAIN AND BEHAVIOR