Spared Nerve Injury Causes Sexually Dimorphic Mechanical Allodynia and Differential Gene Expression in Spinal Cords and Dorsal Root Ganglia in Rats

Sex differences in gene regulation in the dorsal root ganglion after nerve injury

(2019) Kimberly E. Stephens et al.   BMC GENOMICS

Histamine, histamine receptors and neuropathic pain relief

(2019) Ilona Obara et al.   BRITISH JOURNAL OF PHARMACOLOGY

Pharmacological Blockade of Spinal CXCL3/CXCR2 Signaling by NVP CXCR2 20, a Selective CXCR2 Antagonist, Reduces Neuropathic Pain Following Peripheral Nerve Injury

(2019) Anna Piotrowska et al.   Frontiers in Immunology

Antinociceptive effects of novel histamine H3 and H4 receptor antagonists and their influence on morphine analgesia of neuropathic pain in the mouse

(2018) Katarzyna Popiolek-Barczyk et al.   BRITISH JOURNAL OF PHARMACOLOGY

Differential gene expression in trigeminal ganglia of male and female rats following chronic constriction of the infraorbital nerve

(2018) O.A. Korczeniewska et al.   EUROPEAN JOURNAL OF PAIN

A machine-learned analysis of human gene polymorphisms modulating persisting pain points to major roles of neuroimmune processes

(2018) D. Kringel et al.   EUROPEAN JOURNAL OF PAIN

ATF2, but not ATF3, participates in the maintenance of nerve injury-induced tactile allodynia and thermal hyperalgesia

(2018) Ana B Salinas-Abarca et al.   Molecular Pain

Differential Spinal and Supraspinal Activation of Glia in a Rat Model of Morphine Tolerance

(2018) Viljami Jokinen et al.   NEUROSCIENCE

Microglial P2X4R-evoked pain hypersensitivity is sexually dimorphic in rats

(2018) Josiane C.S. Mapplebeck et al.   PAIN

Glial cell type-specific changes in spinal dipeptidyl peptidase 4 expression and effects of its inhibitors in inflammatory and neuropatic pain

(2018) Kornél Király et al.   Scientific Reports

What Makes Surgical Nerve Injury Painful? A 4-9 Year Follow-Up of Patients with Intercostobrachial Nerve Resection in Women Treated for Breast Cancer

(2018) Laura Mustonen et al.   PAIN

Effects of S 38093, an antagonist/inverse agonist of histamine H3 receptors, in models of neuropathic pain in rats

(2017) T. Chaumette et al.   EUROPEAN JOURNAL OF PAIN

PD-L1 inhibits acute and chronic pain by suppressing nociceptive neuron activity via PD-1

(2017) Gang Chen et al.   NATURE NEUROSCIENCE

Erratum: Structural plasticity and reorganisation in chronic pain

(2017) Rohini Kuner et al.   NATURE REVIEWS NEUROSCIENCE

CXCL1/CXCR2 signaling in pathological pain: Role in peripheral and central sensitization

(2017) Rangel L. Silva et al.   NEUROBIOLOGY OF DISEASE

Transient receptor potential vanilloid 6 (TRPV6) in the mouse brain: Distribution and estrous cycle-related changes in the hypothalamus

(2017) Santosh Kumar et al.   NEUROSCIENCE

Inflammation in the pathophysiology of neuropathic pain

(2017) Claudia Sommer et al.   PAIN

High levels of cerebrospinal fluid chemokines point to the presence of neuroinflammation in peripheral neuropathic pain

(2017) Emmanuel Bäckryd et al.   PAIN

Analyses of long non-coding RNA and mRNA profiles in the spinal cord of rats using RNA sequencing during the progression of neuropathic pain in an SNI model

(2017) Jun Zhou et al.   RNA Biology

Sex differences in peripheral not central immune responses to pain-inducing injury

(2017) Douglas M. Lopes et al.   Scientific Reports

Spinal inhibition of p38 MAP kinase reduces inflammatory and neuropathic pain in male but not female mice: Sex-dependent microglial signaling in the spinal cord

(2016) Sarah Taves et al.   BRAIN BEHAVIOR AND IMMUNITY

Chemokine receptor CXCR2 in dorsal root ganglion contributes to the maintenance of inflammatory pain

(2016) De-Li Cao et al.   BRAIN RESEARCH BULLETIN

Central Mechanisms Mediating Thrombospondin-4-induced Pain States

(2016) John Park et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CXCL13 drives spinal astrocyte activation and neuropathic pain via CXCR5

(2016) Bao-Chun Jiang et al.   JOURNAL OF CLINICAL INVESTIGATION

Peripheral nerve injury induces loss of nociceptive neuron-specific Gαi-interacting protein in neuropathic pain rat

(2016) Zhen Liu et al.   Molecular Pain

Selective small molecule angiotensin II type 2 receptor antagonists for neuropathic pain

(2016) Maree T. Smith et al.   PAIN

Pharmacotherapy for neuropathic pain in adults: a systematic review and meta-analysis

(2015) Nanna B Finnerup et al.   LANCET NEUROLOGY

Different immune cells mediate mechanical pain hypersensitivity in male and female mice

(2015) Robert E Sorge et al.   NATURE NEUROSCIENCE

Unravelling Spinal Circuits of Pain and Mechanical Allodynia

(2015) Vijayan Gangadharan et al.   NEURON

Angiotensin II Type 2-Receptor: New Clinically Validated Target in the Treatment of Neuropathic Pain

(2015) ASC Rice et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Trimmomatic: a flexible trimmer for Illumina sequence data

(2014) Anthony M. Bolger et al.   BIOINFORMATICS

Chemokine CXCL1 enhances inflammatory pain and increases NMDA receptor activity and COX-2 expression in spinal cord neurons via activation of CXCR2

(2014) De-Li Cao et al.   EXPERIMENTAL NEUROLOGY

Terminal Deoxynucleotidyl Transferase Establishes and Broadens Antiviral CD8+ T Cell Immunodominance Hierarchies

(2014) S. M. M. Haeryfar et al.   JOURNAL OF IMMUNOLOGY

Painful nerve injury upregulates thrombospondin-4 expression in dorsal root ganglia

(2014) Bin Pan et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Dynorphin Acts as a Neuromodulator to Inhibit Itch in the Dorsal Horn of the Spinal Cord

(2014) Adam P. Kardon et al.   NEURON

TRPV6 calcium channel translocates to the plasma membrane via Orai1-mediated mechanism and controls cancer cell survival

(2014) Maylis Raphaël et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Transcription factor IRF5 drives P2X4R+-reactive microglia gating neuropathic pain

(2014) Takahiro Masuda et al.   Nature Communications

featureCounts: an efficient general purpose program for assigning sequence reads to genomic features

(2013) Y. Liao et al.   BIOINFORMATICS

PainNetworks: A web-based resource for the visualisation of pain-related genes in the context of their network associations

(2013) James R. Perkins et al.   PAIN

Chemokine contribution to neuropathic pain: Respective induction of CXCL1 and CXCR2 in spinal cord astrocytes and neurons

(2013) Zhi-Jun Zhang et al.   PAIN

Higher pain perception and lack of recovery from neuropathic pain in females: A behavioural, immunohistochemical, and proteomic investigation on sex-related differences in mice

(2013) Valentina Vacca et al.   PAIN

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

Thrombospondin-4 Contributes to Spinal Sensitization and Neuropathic Pain States

(2012) D.-S. Kim et al.   JOURNAL OF NEUROSCIENCE

IRF8 Is a Critical Transcription Factor for Transforming Microglia into a Reactive Phenotype

(2012) Takahiro Masuda et al.   Cell Reports

PD-L1 co-stimulation contributes to ligand-induced T cell receptor down-modulation on CD8+T cells

(2011) Katarzyna Karwacz et al.   EMBO Molecular Medicine

Intrinsic and extrinsic control of peripheral T-cell tolerance by costimulatory molecules of the CD28/ B7 family

(2011) Hélène Bour-Jordan et al.   IMMUNOLOGICAL REVIEWS

Patterns of pain: Meta-analysis of microarray studies of pain

(2011) Michael L. LaCroix-Fralish et al.   PAIN

A new definition of neuropathic pain

(2011) Troels S. Jensen et al.   PAIN

A systematic literature review of 10 years of research on sex/gender and experimental pain perception – Part 1: Are there really differences between women and men?

(2011) Mélanie Racine et al.   PAIN

Activating Transcription Factor 3, a Useful Marker for Regenerative Response after Nerve Root Injury

(2011) Hans Lindå et al.   Frontiers in Neurology

Loss of Inhibitory Interneurons in the Dorsal Spinal Cord and Elevated Itch in Bhlhb5 Mutant Mice

(2010) Sarah E. Ross et al.   NEURON

Differential ATF3 expression in dorsal root ganglion neurons reveals the profile of primary afferents engaged by diverse noxious chemical stimuli

(2010) João M. Bráz et al.   PAIN

Improving Bioscience Research Reporting: The ARRIVE Guidelines for Reporting Animal Research

(2010) Carol Kilkenny et al.   PLOS BIOLOGY

Gabapentin Receptor α2δ-1 Is a Neuronal Thrombospondin Receptor Responsible for Excitatory CNS Synaptogenesis

(2009) Çagla Eroglu et al.   CELL

Intrathecally injected Ile-Pro-Ile, an inhibitor of membrane ectoenzyme dipeptidyl peptidase IV, is antihyperalgesic in rats by switching the enzyme from hydrolase to synthase functional mode to generate endomorphin 2

(2009) Kornél Király et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Negative regulators of T-cell activation: potential targets for therapeutic intervention in cancer, autoimmune disease, and persistent infections

(2009) Tsvetelina Pentcheva-Hoang et al.   IMMUNOLOGICAL REVIEWS

T-Cell Infiltration and Signaling in the Adult Dorsal Spinal Cord Is a Major Contributor to Neuropathic Pain-Like Hypersensitivity

(2009) M. Costigan et al.   JOURNAL OF NEUROSCIENCE

Sex, Gender, and Pain: A Review of Recent Clinical and Experimental Findings

(2009) Roger B. Fillingim et al.   JOURNAL OF PAIN

Profiling of dynamically changed gene expression in dorsal root ganglia post peripheral nerve injury and a critical role of injury-induced glial fibrillary acetic protein in maintenance of pain behaviors

(2009) Doo-sik Kim et al.   PAIN

MAP kinase and pain

(2008) Ru-Rong Ji et al.   BRAIN RESEARCH REVIEWS

MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification

(2008) Jürgen Cox et al.   NATURE BIOTECHNOLOGY

Prevalence of chronic pain with neuropathic characteristics in the general population

(2007) Didier Bouhassira et al.   PAIN