Identification of a Novel Cleavage Site and Confirmation of the Effectiveness of NgAgo Gene Editing on RNA Targets

A novel long non-coding RNA-KAT7 is low expressed in colorectal cancer and acts as a tumor suppressor

(2019) Qingmei Wang et al.   Cancer Cell International

CRISPR–Cas13 Precision Transcriptome Engineering in Cancer

(2018) Javier T. Granados-Riveron et al.   CANCER RESEARCH

Zebrafish Embryonic Slow Muscle Is a Rapid System for Genetic Analysis of Sarcomere Organization by CRISPR/Cas9, but Not NgAgo

(2018) Mengxin Cai et al.   MARINE BIOTECHNOLOGY

Ligase IV inhibitor SCR7 enhances gene editing directed by CRISPR–Cas9 and ssODN in human cancer cells

(2018) Zheng Hu et al.   Cell and Bioscience

HPV Oncogene Manipulation Using Nonvirally Delivered CRISPR/Cas9 or Natronobacterium gregoryi Argonaute

(2018) Yeh-Hsing Lao et al.   Advanced Science

Highly efficient genome editing by CRISPR-Cpf1 using CRISPR RNA with a uridinylate-rich 3′-overhang

(2018) Su Bin Moon et al.   Nature Communications

The Expanded Universe of Prokaryotic Argonaute Proteins

(2018) Sergei Ryazansky et al.   mBio

AKR1B10 promotes breast cancer cell migration and invasion via activation of ERK signaling

(2017) Jia Li et al.   Oncotarget

No evidence of genome editing activity from Natronobacterium gregoryi Argonaute (NgAgo) in human cells

(2017) Parisa Javidi-Parsijani et al.   PLoS One

No evidence for genome editing in mouse zygotes and HEK293T human cell line using the DNA-guided Natronobacterium gregoryi Argonaute (NgAgo)

(2017) Nay Chi Khin et al.   PLoS One

RISC assembly: Coordination between small RNAs and Argonaute proteins

(2016) Hotaka Kobayashi et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

NgAgo-based fabp11a gene knockdown causes eye developmental defects in zebrafish

(2016) Jialing Qi et al.   CELL RESEARCH

Failure to detect DNA-guided genome editing using Natronobacterium gregoryi Argonaute

(2016) Seung Hwan Lee et al.   NATURE BIOTECHNOLOGY

Optimized sgRNA design to maximize activity and minimize off-target effects of CRISPR-Cas9

(2016) John G Doench et al.   NATURE BIOTECHNOLOGY

Questions about NgAgo

(2016) Shawn Burgess et al.   Protein & Cell

Argonaute of the archaeon Pyrococcus furiosus is a DNA-guided nuclease that targets cognate DNA

(2015) Daan C. Swarts et al.   NUCLEIC ACIDS RESEARCH

DNA-guided DNA interference by a prokaryotic Argonaute

(2014) Daan C. Swarts et al.   NATURE

Molecular Mechanisms of RNA Interference

(2013) Ross C. Wilson et al.   Annual Review of Biophysics

Argonaute proteins: functional insights and emerging roles

(2013) Gunter Meister   NATURE REVIEWS GENETICS

Genome-Scale CRISPR-Cas9 Knockout Screening in Human Cells

(2013) Ophir Shalem et al.   SCIENCE