Elevated soluble amyloid beta protofibrils in Down syndrome and Alzheimer's disease

Characterization of monomeric and soluble aggregated Aβ in Down’s syndrome and Alzheimer’s disease brains

(2021) Eleni Gkanatsiou et al.   NEUROSCIENCE LETTERS

Association Between Longitudinal Plasma Neurofilament Light and Neurodegeneration in Patients With Alzheimer Disease

(2019) Niklas Mattsson et al.   JAMA Neurology

Patterns and severity of vascular amyloid in Alzheimer’s disease associated with duplications and missense mutations in APP gene, Down syndrome and sporadic Alzheimer’s disease

(2018) David M. A. Mann et al.   ACTA NEUROPATHOLOGICA

Down syndrome, beta-amyloid and neuroimaging

(2018) Elizabeth Head et al.   FREE RADICAL BIOLOGY AND MEDICINE

Specific Uptake of an Amyloid-β Protofibril-Binding Antibody-Tracer in AβPP Transgenic Mouse Brain

(2018) Kristina Magnusson et al.   JOURNAL OF ALZHEIMERS DISEASE

The Murine Version of BAN2401 (mAb158) Selectively Reduces Amyloid-β Protofibrils in Brain and Cerebrospinal Fluid of tg-ArcSwe Mice

(2018) Stina Tucker et al.   JOURNAL OF ALZHEIMERS DISEASE

Plasma and CSF biomarkers for the diagnosis of Alzheimer's disease in adults with Down syndrome: a cross-sectional study

(2018) Juan Fortea et al.   LANCET NEUROLOGY

Comparison of longitudinal Aβ in non-demented elderly and Down syndrome

(2018) Dana L. Tudorascu et al.   NEUROBIOLOGY OF AGING

Predictors of Age of Diagnosis and Survival of Alzheimer’s Disease in Down Syndrome

(2017) Amanda Sinai et al.   JOURNAL OF ALZHEIMERS DISEASE

Down Syndrome, Partial Trisomy 21, and Absence of Alzheimer’s Disease: The Role of APP

(2017) Eric Doran et al.   JOURNAL OF ALZHEIMERS DISEASE

Down syndrome: age-dependence of PiB binding in postmortem frontal cortex across the lifespan

(2017) Harry LeVine et al.   NEUROBIOLOGY OF AGING

Normalizing the gene dosage of Dyrk1A in a mouse model of Down syndrome rescues several Alzheimer's disease phenotypes

(2017) Susana García-Cerro et al.   NEUROBIOLOGY OF DISEASE

Elucidating Pathogenic Mechanisms of Early-onset Alzheimer's Disease in Down Syndrome Patients

(2017) Masashi Asai et al.   YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN

The pattern of amyloid accumulation in the brains of adults with Down syndrome

(2016) Tiina Annus et al.   Alzheimers & Dementia

Safety and tolerability of BAN2401 - a clinical study in Alzheimer’s disease with a protofibril selective Aβ antibody

(2016) Veronika Logovinsky et al.   Alzheimers Research & Therapy

Aging in Down Syndrome and the Development of Alzheimer's Disease Neuropathology

(2015) Elizabeth Head et al.   Current Alzheimer Research

Perspectives on future Alzheimer therapies: amyloid-β protofibrils - a new target for immunotherapy with BAN2401 in Alzheimer’s disease

(2014) Lars Lannfelt et al.   Alzheimers Research & Therapy

Characterization of AZD4694, a novel fluorinated Aβ plaque neuroimaging PET radioligand

(2010) Anders Juréus et al.   JOURNAL OF NEUROCHEMISTRY

A fibril-specific, conformation-dependent antibody recognizes a subset of Aβ plaques in Alzheimer disease, Down syndrome and Tg2576 transgenic mouse brain

(2009) Floyd Sarsoza et al.   ACTA NEUROPATHOLOGICA

The genetic architecture of Down syndrome phenotypes revealed by high-resolution analysis of human segmental trisomies

(2009) J. O. Korbel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mosaicism for Trisomy 21 in a Patient With Young-Onset Dementia

(2008) John M. Ringman et al.   ARCHIVES OF NEUROLOGY