Emerging importance of ACE2 in external stratified epithelial tissues

Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro

(2020) Manli Wang et al.   CELL RESEARCH

Angiotensin-converting enzyme 2 (ACE2) as a SARS-CoV-2 receptor: molecular mechanisms and potential therapeutic target

(2020) Haibo Zhang et al.   INTENSIVE CARE MEDICINE

Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding

(2020) Roujian Lu et al.   LANCET

A pneumonia outbreak associated with a new coronavirus of probable bat origin

(2020) Peng Zhou et al.   NATURE

Pathological findings of COVID-19 associated with acute respiratory distress syndrome

(2020) Zhe Xu et al.   Lancet Respiratory Medicine

SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor

(2020) Markus Hoffmann et al.   CELL

Soluble angiotensin-converting enzyme 2: a potential approach for coronavirus infection therapy?

(2020) Daniel Batlle et al.   CLINICAL SCIENCE

The pivotal link between ACE2 deficiency and SARS-CoV-2 infection

(2020) Paolo Verdecchia et al.   European Journal of Internal Medicine

Expression of SARS-CoV-2 receptor ACE2 and TMPRSS2 in human primary conjunctival and pterygium cell lines and in mouse cornea

(2020) Di Ma et al.   EYE

High expression of ACE2 on the keratinocytes reveals skin as a potential target for SARS-CoV-2

(2020) Xiaotong Xue et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Renal denervation improves vascular endothelial dysfunction by inducing autophagy via AMPK/mTOR signaling activation in a rat model of type 2 diabetes mellitus with insulin resistance

(2020) Yong Wang et al.   ACTA DIABETOLOGICA

Inhibitory Effect of Valsartan on Pterygium Fibroblasts

(2020) Erkut Küçük et al.   CORNEA

The Role of the Renin‐Angiotensin System in Skin Physiology and Pathophysiology

(2020) Igor Maciel Souza Silva et al.   EXPERIMENTAL DERMATOLOGY

The ACE2‐deficient mouse: A model for a cytokine storm‐driven inflammation

(2020) Junyi Wang et al.   FASEB JOURNAL

MicroRNA-122 aggravates angiotensin II-mediated apoptosis and autophagy imbalance in rat aortic adventitial fibroblasts via the modulation of SIRT6-elabela-ACE2 signaling

(2020) Juan-Juan Song et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Secukinumab Lowers Expression of ACE2 in Affected Skin of Patients With Psoriasis

(2020) James G. Krueger et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Vitamin D improves sunburns by increasing autophagy in M2 macrophages

(2019) Lopa. M. Das et al.   Autophagy

The renin angiotensin aldosterone system and its therapeutic targets

(2019) Katrina M. Mirabito Colafella et al.   EXPERIMENTAL EYE RESEARCH

Angiotensin-converting enzyme 2 regulates autophagy in acute lung injury through AMPK/mTOR signaling

(2019) Xiaomiao Zhang et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

FGF23-Mediated Activation of Local RAAS Promotes Cardiac Hypertrophy and Fibrosis

(2019) Ineke Böckmann et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Novel Variants of Angiotensin Converting Enzyme-2 of Shorter Molecular Size to Target the Kidney Renin Angiotensin System

(2019) Jan Wysocki et al.   Biomolecules

Topical Reformulation of Valsartan for Treatment of Chronic Diabetic Wounds

(2018) Peter Abadir et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Skin Stem Cells in Silence, Action, and Cancer

(2018) Elaine Fuchs   Stem Cell Reports

Balance and circumstance: The renin angiotensin system in wound healing and fibrosis

(2018) Rocco Bernasconi et al.   CELLULAR SIGNALLING

MiRNA-30e mediated cardioprotection of ACE2 in rats with Doxorubicin-induced heart failure through inhibiting cardiomyocytes autophagy

(2017) Lei Lai et al.   LIFE SCIENCES

Vitamin D alleviates lipopolysaccharide-induced acute lung injury via regulation of the renin-angiotensin system

(2017) Jun Xu et al.   Molecular Medicine Reports

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

(2016) Daniel J Klionsky et al.   Autophagy

MicroRNAs-103/107 coordinately regulate macropinocytosis and autophagy

(2016) Jong Kook Park et al.   JOURNAL OF CELL BIOLOGY

Angiotensin-converting enzyme 2 activator diminazene aceturate prevents lipopolysaccharide-induced inflammation by inhibiting MAPK and NF-κB pathways in human retinal pigment epithelium

(2016) Lifei Tao et al.   Journal of Neuroinflammation

Transforming growth factor beta (TGF-β) isoforms in wound healing and fibrosis

(2016) Michael K. Lichtman et al.   WOUND REPAIR AND REGENERATION

AAV8-Mediated Angiotensin-Converting Enzyme 2 Gene Delivery Prevents Experimental Autoimmune Uveitis by Regulating MAPK, NF-κB and STAT3 Pathways

(2016) Yiguo Qiu et al.   Scientific Reports

Ang-(1-7) promotes the migration and invasion of human renal cell carcinoma cells via Mas-mediated AKT signaling pathway

(2015) Shuai Zheng et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Tissue Renin–Angiotensin System in Lacrimal Gland Fibrosis in a Murine Model of Chronic Graft-Versus-Host Disease

(2015) Saori Yaguchi et al.   CORNEA

The expression of Mas-receptor of the renin–angiotensin system in the human eye

(2015) A. Vaajanen et al.   GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY

Angiotensins as therapeutic targets beyond heart disease

(2015) Danielle Gomes Passos-Silva et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Atlas of tissue renin-angiotensin-aldosterone system in human: A transcriptomic meta-analysis

(2015) Ali Nehme et al.   Scientific Reports

Effects of RAS inhibitors on diabetic retinopathy: a systematic review and meta-analysis

(2015) Bin Wang et al.   Lancet Diabetes & Endocrinology

Angiotensin-(1–7) abolishes AGE-induced cellular hypertrophy and myofibroblast transformation via inhibition of ERK1/2

(2014) Ebaa M. Alzayadneh et al.   CELLULAR SIGNALLING

Angiotensin II: immunohistochemical study in Sardinian pterygium

(2014) P. Demurtas et al.   EUROPEAN JOURNAL OF HISTOCHEMISTRY

Wounding the cornea to learn how it heals

(2014) Mary Ann Stepp et al.   EXPERIMENTAL EYE RESEARCH

Molecular pathology of emerging coronavirus infections

(2014) Lisa E Gralinski et al.   JOURNAL OF PATHOLOGY

Expression of classical components of the renin-angiotensin system in the human eye

(2014) Andrew JR White et al.   JOURNAL OF THE RENIN-ANGIOTENSIN-ALDOSTERONE SYSTEM

ACE and ACE2 expression in normal and malignant skin lesions

(2013) Jedrzej Grzegrzolka et al.   FOLIA HISTOCHEMICA ET CYTOBIOLOGICA

The ocular renin–angiotensin system: A therapeutic target for the treatment of ocular disease

(2013) Michael J. Giese et al.   PHARMACOLOGY & THERAPEUTICS

Angiotensin-converting enzyme 2: enhancing the degradation of angiotensin II as a potential therapy for diabetic nephropathy

(2011) Daniel Batlle et al.   KIDNEY INTERNATIONAL

ACE2 and Ang-(1-7) Confer Protection Against Development of Diabetic Retinopathy

(2011) Amrisha Verma et al.   MOLECULAR THERAPY

Reduced angiogenesis and delay in wound healing in angiotensin II type 1a receptor-deficient mice

(2009) Maya Kurosaka et al.   BIOMEDICINE & PHARMACOTHERAPY

Autophagy: A lysosomal degradation pathway with a central role in health and disease

(2008) Eeva-Liisa Eskelinen et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Update on tissue renin–angiotensin systems

(2008) Michael Bader et al.   JOURNAL OF MOLECULAR MEDICINE-JMM