Fenofibrate, a PPARα agonist, reduces hepatic fat accumulation through the upregulation of TFEB-mediated lipophagy
Published 2021 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Fenofibrate, a PPARα agonist, reduces hepatic fat accumulation through the upregulation of TFEB-mediated lipophagy
Authors
Keywords
Nonalcoholic fatty liver disease, Autophagy, Lipophagy, Transcription factor EB, Fenofibrate, Peroxisome proliferator-activated receptor α, Mucolipin 1, Calcium signaling
Journal
METABOLISM-CLINICAL AND EXPERIMENTAL
Volume 120, Issue -, Pages 154798
Publisher
Elsevier BV
Online
2021-05-11
DOI
10.1016/j.metabol.2021.154798
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Curcumin ameliorates oxidative stress-induced intestinal barrier injury and mitochondrial damage by promoting Parkin dependent mitophagy through AMPK-TFEB signal pathway
- (2019) Shuting Cao et al. FREE RADICAL BIOLOGY AND MEDICINE
- Experimental design and analysis and their reporting II: updated and simplified guidance for authors and peer reviewers
- (2018) Michael J Curtis et al. BRITISH JOURNAL OF PHARMACOLOGY
- The complex relationship between TFEB transcription factor phosphorylation and subcellular localization
- (2018) Rosa Puertollano et al. EMBO JOURNAL
- A novel autophagy enhancer as a therapeutic agent against metabolic syndrome and diabetes
- (2018) Hyejin Lim et al. Nature Communications
- Procyanidin B2 ameliorates free fatty acids-induced hepatic steatosis through regulating TFEB-mediated lysosomal pathway and redox state
- (2018) Hongming Su et al. FREE RADICAL BIOLOGY AND MEDICINE
- Exendin-4, a glucagon-like peptide-1 receptor agonist, reduces hepatic steatosis and endoplasmic reticulum stress by inducing nuclear factor erythroid-derived 2-related factor 2 nuclear translocation
- (2018) Jin Yoo et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
- AMPK: guardian of metabolism and mitochondrial homeostasis
- (2017) Sébastien Herzig et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- TFEB-mediated increase in peripheral lysosomes regulates store-operated calcium entry
- (2017) Luigi Sbano et al. Scientific Reports
- TFEB and TFE3: Linking Lysosomes to Cellular Adaptation to Stress
- (2016) Nina Raben et al. Annual Review of Cell and Developmental Biology
- AMPK governs lineage specification through Tfeb-dependent regulation of lysosomes
- (2016) Nathan P. Young et al. GENES & DEVELOPMENT
- Protein kinase C controls lysosome biogenesis independently of mTORC1
- (2016) Yang Li et al. NATURE CELL BIOLOGY
- PPARα in lysosomal biogenesis: A perspective
- (2016) Arunava Ghosh et al. PHARMACOLOGICAL RESEARCH
- Regulation of autophagy by Ca2+
- (2016) Fang Sun et al. TUMOR BIOLOGY
- Intracellular calcium signaling regulates autophagy via calcineurin-mediated TFEB dephosphorylation
- (2015) Yanju Tong et al. Autophagy
- Fenofibrate activates Nrf2 through p62-dependent Keap1 degradation
- (2015) Jeong Su Park et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Molecular mechanism of PPARα action and its impact on lipid metabolism, inflammation and fibrosis in non-alcoholic fatty liver disease
- (2015) Michal Pawlak et al. JOURNAL OF HEPATOLOGY
- Fenofibrate pre-treatment suppressed inflammation by activating phosphoinositide 3 kinase/protein kinase B (PI3K/Akt) signaling in renal ischemia-reperfusion injury
- (2015) Feng-jie Yang et al. Journal of Huazhong University of Science and Technology-Medical Sciences
- Lysosomal calcium signalling regulates autophagy through calcineurin and TFEB
- (2015) Diego L. Medina et al. NATURE CELL BIOLOGY
- Degradation of lipid droplet-associated proteins by chaperone-mediated autophagy facilitates lipolysis
- (2015) Susmita Kaushik et al. NATURE CELL BIOLOGY
- Nutrient-sensing nuclear receptors coordinate autophagy
- (2014) Jae Man Lee et al. NATURE
- Fenofibrate and dipyridamole treatments in low-doses either alone or in combination blunted the development of nephropathy in diabetic rats
- (2014) Pitchai Balakumar et al. PHARMACOLOGICAL RESEARCH
- The Nutrient-Responsive Transcription Factor TFE3 Promotes Autophagy, Lysosomal Biogenesis, and Clearance of Cellular Debris
- (2014) J. A. Martina et al. Science Signaling
- Fenofibrate, a PPARα agonist, has renoprotective effects in mice by enhancing renal lipolysis
- (2011) Yuki Tanaka et al. KIDNEY INTERNATIONAL
- TFEB Links Autophagy to Lysosomal Biogenesis
- (2011) C. Settembre et al. SCIENCE
- AMPK-Dependent Metabolic Regulation by PPAR Agonists
- (2010) Woo Hyung Lee et al. PPAR Research
- Autophagy regulates lipid metabolism
- (2009) Rajat Singh et al. NATURE
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now