MALDI imaging mass spectrometry: an emerging tool in neurology

In situ metabolite and lipid analysis of GluN2D−/− and wild-type mice after ischemic stroke using MALDI MSI

(2020) William T. Andrews et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Integrated molecular imaging technologies for investigation of metals in biological systems: A brief review

(2020) William J. Perry et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Brain delivery and activity of a lysosomal enzyme using a blood-brain barrier transport vehicle in mice

(2020) Julie C. Ullman et al.   Science Translational Medicine

Multimodal Imaging Mass Spectrometry: Next Generation Molecular Mapping in Biology and Medicine

(2020) Elizabeth Kathleen Neumann et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Involvement of Lipids in Alzheimer’s Disease Pathology and Potential Therapies

(2020) Hannah Chew et al.   Frontiers in Physiology

MALDI Mass Spectrometry Imaging in a Primary Demyelination Model of Murine Spinal Cord

(2020) Emily R. Sekera et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Metabolomic analysis and mass spectrometry imaging after neonatal stroke and cell therapies in mouse brains

(2020) Emi Tanaka et al.   Scientific Reports

Distinguishing core from penumbra by lipid profiles using Mass Spectrometry Imaging in a transgenic mouse model of ischemic stroke

(2019) I. A. Mulder et al.   Scientific Reports

Traumatic brain injury: neuropathological, neurocognitive and neurobehavioral sequelae

(2019) Dragan Pavlovic et al.   Pituitary

Quantification and assessment of detection capability in imaging mass spectrometry using a revised mimetic tissue model

(2019) Jeremy A Barry et al.   Bioanalysis

Metabolites and Lipids Associated with Fetal Swine Anatomy via Desorption Electrospray Ionization – Mass Spectrometry Imaging

(2019) Marisol León et al.   Scientific Reports

Imaging Mass Spectrometry: A New Tool to Assess Molecular Underpinnings of Neurodegeneration

(2019) Kevin Chen et al.   Metabolites

Matrix-Assisted Laser Desorption/Ionization-Mass Spectrometry Imaging of Lipids in Experimental Model of Traumatic Brain Injury Detecting Acylcarnitines as Injury Related Markers

(2019) Khalil Mallah et al.   ANALYTICAL CHEMISTRY

Comprehensive mapping of neurotransmitter networks by MALDI–MS imaging

(2019) Mohammadreza Shariatgorji et al.   NATURE METHODS

Evaluation of lipid coverage and high spatial resolution MALDI-imaging capabilities of oversampling combined with laser post-ionisation

(2019) Andrew P. Bowman et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

The global burden of neurological disorders: translating evidence into policy

(2019) Valery L Feigin et al.   LANCET NEUROLOGY

Cerebral Lipid Dynamics in Chronic Cerebral Hypoperfusion Model by DESI-MS Imaging

(2019) Dryelle L.R. Severiano et al.   NEUROSCIENCE

Matrix-Assisted Laser Desorption Ionization Mapping of Lysophosphatidic Acid Changes after Traumatic Brain Injury and the Relationship to Cellular Pathology

(2018) Whitney S. McDonald et al.   AMERICAN JOURNAL OF PATHOLOGY

MALDI matrices for low molecular weight compounds: an endless story?

(2018) Cosima Damiana Calvano et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Traumatic Brain Injury: Classification, Models and Markers

(2018) Dema Najem et al.   Biochemistry and Cell Biology

Lysophosphatidic acid induces neuronal cell death via activation of asparagine endopeptidase in cerebral ischemia-reperfusion injury

(2018) Chao Wang et al.   EXPERIMENTAL NEUROLOGY

Subventricular Zone Lipidomic Architecture Loss in Huntington's Disease

(2018) Mandana Hunter et al.   JOURNAL OF NEUROCHEMISTRY

Matrix-assisted laser desorption/ionization imaging mass spectrometry of intraperitoneally injected danegaptide (ZP1609) for treatment of stroke-reperfusion injury in mice

(2018) Jasmine S.H. Wang et al.   RAPID COMMUNICATIONS IN MASS SPECTROMETRY

Multi-modal imaging of long-term recovery post-stroke by positron emission tomography and matrix-assisted laser desorption/ionisation mass spectrometry

(2018) Fiona Henderson et al.   RAPID COMMUNICATIONS IN MASS SPECTROMETRY

Mass Spectrometry Imaging of Lipids: Generation of Untargeted Consensus Spectra Reveals Spatial Distributions in Niemann-Pick Disease, Type C1

(2018) Fernando Tobias et al.   JOURNAL OF LIPID RESEARCH

Chloroquine Restores Ganglioside Homeostasis and Improves Pathological and Behavioral Outcomes Post-stroke in the Rat

(2018) Sarah Caughlin et al.   MOLECULAR NEUROBIOLOGY

Spatial and molecular changes of mouse brain metabolism in response to immunomodulatory treatment with teriflunomide as visualized by MALDI-MSI

(2018) Ignacy Rzagalinski et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

The physiology of foamy phagocytes in multiple sclerosis

(2018) Elien Grajchen et al.   Acta Neuropathologica Communications

Protein identification strategies in MALDI imaging mass spectrometry: a brief review

(2018) Daniel J Ryan et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

MALDI imaging mass spectrometry analysis—A new approach for protein mapping in multiple sclerosis brain lesions

(2017) Giuseppina Maccarrone et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Feasibility Assessment of a MALDI FTICR Imaging Approach for the 3D Reconstruction of a Mouse Lung

(2017) E. Ellen Jones et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Active liver X receptor signaling in phagocytes in multiple sclerosis lesions

(2017) Jo Mailleux et al.   Multiple Sclerosis Journal

Region-specific bioconversion of dynorphin neuropeptide detected by in situ histochemistry and MALDI imaging mass spectrometry

(2017) Erik Bivehed et al.   PEPTIDES

Active liver X receptor signaling in phagocytes in multiple sclerosis lesions

(2017) Jo Mailleux et al.   Multiple Sclerosis Journal

Distinct deposition of amyloid-β species in brains with Alzheimer’s disease pathology visualized with MALDI imaging mass spectrometry

(2017) Nobuto Kakuda et al.   Acta Neuropathologica Communications

Tissue Localization of Glycosphingolipid Accumulation in a Gaucher Disease Mouse Brain by LC-ESI-MS/MS and High-Resolution MALDI Imaging Mass Spectrometry

(2017) E. Ellen Jones et al.   SLAS Discovery

Multimodal detection of GM2 and GM3 lipid species in the brain of mucopolysaccharidosis type II mouse by serial imaging mass spectrometry and immunohistochemistry

(2016) Martin Dufresne et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Imaging mass spectrometry in drug development and toxicology

(2016) Oskar Karlsson et al.   ARCHIVES OF TOXICOLOGY

Imaging of amyloid-β in Alzheimer's disease transgenic mouse brains with ToF-SIMS using immunoliposomes

(2016) Louise Carlred et al.   Biointerphases

Imaging mass spectrometry reveals loss of polyunsaturated cardiolipins in the cortical contusion, hippocampus, and thalamus after traumatic brain injury

(2016) Louis J. Sparvero et al.   JOURNAL OF NEUROCHEMISTRY

Mass spectrometry imaging of amino neurotransmitters: a comparison of derivatization methods and application in mouse brain tissue

(2016) Clara Esteve et al.   Metabolomics

Lipid and metabolite profiles of human brain tumors by desorption electrospray ionization-MS

(2016) Alan K. Jarmusch et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Imaging of amyloid-β in Alzheimer's disease transgenic mouse brains with ToF-SIMS using immunoliposomes

(2016) Louise Carlred et al.   Biointerphases

Hippocampal lipid differences in Alzheimer's disease: a human brain study using matrix-assisted laser desorption/ionization-imaging mass spectrometry

(2016) Lakshini H. S. Mendis et al.   Brain and Behavior

Proteomic Profiling in the Brain of CLN1 Disease Model Reveals Affected Functional Modules

(2015) Saara Tikka et al.   NEUROMOLECULAR MEDICINE

Increased Expression of Simple Ganglioside Species GM2 and GM3 Detected by MALDI Imaging Mass Spectrometry in a Combined Rat Model of Aβ Toxicity and Stroke

(2015) Sarah Caughlin et al.   PLoS One

On-Tissue Localization of Ceramides and Other Sphingolipids by MALDI Mass Spectrometry Imaging

(2014) E. Ellen Jones et al.   ANALYTICAL CHEMISTRY

Simultaneous Imaging of Amyloid-β and Lipids in Brain Tissue Using Antibody-Coupled Liposomes and Time-of-Flight Secondary Ion Mass Spectrometry

(2014) Louise Carlred et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Direct Targeted Quantitative Molecular Imaging of Neurotransmitters in Brain Tissue Sections

(2014) Mohammadreza Shariatgorji et al.   NEURON

MALDI imaging mass spectrometry to investigate endogenous peptides in an animal model of Usher's disease

(2014) Bijon Chatterji et al.   PROTEOMICS

Systemic delivery of P42 peptide: a new weapon to fight Huntington’s disease

(2014) Yoan Arribat et al.   Acta Neuropathologica Communications

Mass Spectrometry Imaging, an Emerging Technology in Neuropsychopharmacology

(2013) Mohammadreza Shariatgorji et al.   NEUROPSYCHOPHARMACOLOGY

Visualization and quantification of cerebral metabolic fluxes of glucose in awake mice

(2013) Yuki Sugiura et al.   PROTEOMICS

Myelin alters the inflammatory phenotype of macrophages by activating PPARs

(2013) Jeroen FJ Bogie et al.   Acta Neuropathologica Communications

Time-of-flight secondary ion mass spectrometry (TOF-SIMS) imaging reveals cholesterol overload in the cerebral cortex of Alzheimer disease patients

(2012) Adina N. Lazar et al.   ACTA NEUROPATHOLOGICA

A new combination MALDI matrix for small molecule analysis: application to imaging mass spectrometry for drugs and metabolites

(2012) Selina Rahman Shanta et al.   ANALYST

New Analysis Workflow for MALDI Imaging Mass Spectrometry: Application to the Discovery and Identification of Potential Markers of Childhood Absence Epilepsy

(2012) Mélanie Lagarrigue et al.   JOURNAL OF PROTEOME RESEARCH

MALDI Imaging Mass Spectrometry of Neuropeptides in Parkinson's Disease

(2012) Jörg Hanrieder et al.   Jove-Journal of Visualized Experiments

Molecular imaging and depth profiling by mass spectrometry—SIMS, MALDI or DESI?

(2011) John C. Vickerman   ANALYST

MALDI Imaging of Lipid Biochemistry in Tissues by Mass Spectrometry

(2011) Karin A. Zemski Berry et al.   CHEMICAL REVIEWS

The evolving field of imaging mass spectrometry and its impact on future biological research

(2011) Jeramie D. Watrous et al.   JOURNAL OF MASS SPECTROMETRY

Imaging Mass Spectrometry Detection of Gangliosides Species in the Mouse Brain following Transient Focal Cerebral Ischemia and Long-Term Recovery

(2011) Shawn N. Whitehead et al.   PLoS One

Mass Spectrometric Imaging for Biomedical Tissue Analysis

(2010) Kamila Chughtai et al.   CHEMICAL REVIEWS

MALDI Imaging Mass Spectrometry - Painting Molecular Pictures

(2010) Kristina Schwamborn et al.   Molecular Oncology

Imaging MALDI Mass Spectrometry Using an Oscillating Capillary Nebulizer Matrix Coating System and Its Application to Analysis of Lipids in Brain from a Mouse Model of Tay−Sachs/Sandhoff Disease

(2008) Yanfeng Chen et al.   ANALYTICAL CHEMISTRY