Does serotonin deficiency lead to anosmia, ageusia, dysfunctional chemesthesis and increased severity of illness in COVID-19?
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Title
Does serotonin deficiency lead to anosmia, ageusia, dysfunctional chemesthesis and increased severity of illness in COVID-19?
Authors
Keywords
Coronavirus, SARS-CoV-2, COVID-19, Anosmia, Ageusia, Chemesthesis, Tryptophan, Serotonin, SSRI, Hypoxia, TRP channel, Melatonin, Niacin, NAD
Journal
MEDICAL HYPOTHESES
Volume 153, Issue -, Pages 110627
Publisher
Elsevier BV
Online
2021-06-06
DOI
10.1016/j.mehy.2021.110627
References
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Related references
Note: Only part of the references are listed.- Neuroinvasion of SARS-CoV-2 in human and mouse brain
- (2021) Eric Song et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Prevalence and 6‐month recovery of olfactory dysfunction: a multicentre study of 1363 COVID‐19 patients
- (2021) J. R. Lechien et al. JOURNAL OF INTERNAL MEDICINE
- Neurological infection with SARS-CoV-2 — the story so far
- (2021) Tom Solomon Nature Reviews Neurology
- Pineal hormone melatonin as an adjuvant treatment for COVID‑19 (Review)
- (2021) Marilena Vlachou et al. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
- Potential intestinal infection and faecal–oral transmission of SARS-CoV-2
- (2021) Meng Guo et al. Nature Reviews Gastroenterology & Hepatology
- Severe COVID‐19 is marked by dysregulated serum levels of carboxypeptidase A3 and serotonin
- (2021) Rodolfo Soria‐Castro et al. JOURNAL OF LEUKOCYTE BIOLOGY
- COVID-19 patients with respiratory failure: what can we learn from aviation medicine?
- (2020) William Ottestad et al. BRITISH JOURNAL OF ANAESTHESIA
- Olfactory and gustatory dysfunctions as a clinical presentation of mild-to-moderate forms of the coronavirus disease (COVID-19): a multicenter European study
- (2020) Jerome R. Lechien et al. EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY
- Potential pathogenesis of ageusia and anosmia in COVID‐19 patients
- (2020) Luigi Angelo Vaira et al. International Forum of Allergy & Rhinology
- Magnetic Resonance Imaging Alteration of the Brain in a Patient With Coronavirus Disease 2019 (COVID-19) and Anosmia
- (2020) Letterio S. Politi et al. JAMA Neurology
- Constitutionally High Serotonin Tone Favors Obesity: Study on Rat Sublines With Altered Serotonin Homeostasis
- (2020) Maja Kesić et al. Frontiers in Neuroscience
- Happy Hypoxemia in COVID-19—A Neural Hypothesis
- (2020) Anoop U.R. et al. ACS Chemical Neuroscience
- Taste and smell disorders in COVID-19 patients: role of Interleukin-6
- (2020) Angela Pia Cazzolla et al. ACS Chemical Neuroscience
- Proinflammatory Cytokines in the Olfactory Mucosa Result in COVID-19 Induced Anosmia
- (2020) Abolfazl Torabi et al. ACS Chemical Neuroscience
- Why COVID-19 Silent Hypoxemia Is Baffling to Physicians
- (2020) Martin J. Tobin et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Spectrum of neuropsychiatric manifestations in COVID-19
- (2020) Krishna Nalleballe et al. BRAIN BEHAVIOR AND IMMUNITY
- Anxiety and depression in COVID-19 survivors: Role of inflammatory and clinical predictors
- (2020) Mario Gennaro Mazza et al. BRAIN BEHAVIOR AND IMMUNITY
- More than smell – COVID-19 is associated with severe impairment of smell, taste, and chemesthesis
- (2020) Valentina Parma et al. CHEMICAL SENSES
- Is loss of sense of smell a diagnostic marker in COVID‐19: A Systematic Review and Meta‐analysis
- (2020) John Rocke et al. CLINICAL OTOLARYNGOLOGY
- The Loss of Smell and Taste in the COVID-19 Outbreak: a Tale of Many Countries
- (2020) Joaquim Mullol et al. CURRENT ALLERGY AND ASTHMA REPORTS
- A structural equation model to examine the clinical features of mild‐to‐moderate COVID‐19: A multicenter Italian study
- (2020) Maria Rosaria Barillari et al. JOURNAL OF MEDICAL VIROLOGY
- Smell and Taste Dysfunction in Patients With COVID-19: A Systematic Review and Meta-analysis
- (2020) Akosua Adom Agyeman et al. MAYO CLINIC PROCEEDINGS
- COVID-19 and the Chemical Senses: Supporting Players Take Center Stage
- (2020) Keiland W. Cooper et al. NEURON
- COVID-19 Pulmonary and Olfactory Dysfunctions: Is the Chemokine CXCL10 the Common Denominator?
- (2020) Antonio Oliviero et al. NEUROSCIENTIST
- Dysgeusia in COVID-19: Possible Mechanisms and Implications
- (2020) Francina Lozada-Nur et al. Oral Surgery Oral Medicine Oral Pathology Oral Radiology
- A mechanistic model and therapeutic interventions for COVID-19 involving a RAS-mediated bradykinin storm
- (2020) Michael R Garvin et al. eLife
- Non-neuronal expression of SARS-CoV-2 entry genes in the olfactory system suggests mechanisms underlying COVID-19-associated anosmia
- (2020) David H. Brann et al. Science Advances
- Olfactory bulb MRI and paranasal sinus CT findings in persistent COVID-19 anosmia
- (2020) Sedat Giray Kandemirli et al. ACADEMIC RADIOLOGY
- COVID-19 and anosmia: A review based on up-to-date knowledge
- (2020) Xiangming Meng et al. AMERICAN JOURNAL OF OTOLARYNGOLOGY
- On Happy Hypoxia and on Sadly Ignored “Acute Vascular Distress Syndrome” in COVID-19 Patients
- (2020) Vincent Jounieaux et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- “Silent” Presentation of Hypoxemia and Cardiorespiratory Compensation in COVID-19
- (2020) Philip E. Bickler et al. ANESTHESIOLOGY
- Surveying Chemosensory Dysfunction in COVID-19
- (2020) Barry G Green CHEMICAL SENSES
- Frequency and Clinical Utility of Olfactory Dysfunction in COVID-19: a Systematic Review and Meta-analysis
- (2020) Khang Wen Pang et al. CURRENT ALLERGY AND ASTHMA REPORTS
- Be well: A potential role for vitamin B in COVID-19
- (2020) Hira Shakoor et al. MATURITAS
- Anosmia in COVID-19: Underlying Mechanisms and Assessment of an Olfactory Route to Brain Infection
- (2020) Rafal Butowt et al. NEUROSCIENTIST
- The olfactory deficits of depressed patients are restored after remission with venlafaxine treatment
- (2020) Romain Colle et al. PSYCHOLOGICAL MEDICINE
- Neuropilin-1 is a host factor for SARS-CoV-2 infection
- (2020) James L. Daly et al. SCIENCE
- Neuropilin-1 facilitates SARS-CoV-2 cell entry and infectivity
- (2020) Ludovico Cantuti-Castelvetri et al. SCIENCE
- Modeling lung perfusion abnormalities to explain early COVID-19 hypoxemia
- (2020) Jacob Herrmann et al. Nature Communications
- Can selective serotonin reuptake inhibitors have a neuroprotective effect during COVID-19?
- (2020) Luis H.A. Costa et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Fluvoxamine vs Placebo and Clinical Deterioration in Outpatients With Symptomatic COVID-19
- (2020) Eric J. Lenze et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Smell and Taste in Severe CoViD-19: Self-Reported vs. Testing
- (2020) Andrea Mazzatenta et al. Frontiers in Medicine
- Depletion of angiotensin-converting enzyme 2 reduces brain serotonin and impairs the running-induced neurogenic response
- (2018) Friederike Klempin et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Hypobaric hypoxia exposure in rats differentially alters antidepressant efficacy of the selective serotonin reuptake inhibitors fluoxetine, paroxetine, escitalopram and sertraline
- (2018) Shami Kanekar et al. PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR
- Differential serotonergic modulation across the main and accessory olfactory bulbs
- (2017) Zhenbo Huang et al. JOURNAL OF PHYSIOLOGY-LONDON
- Incidence of Obstructive Sleep Apnea in Elderly Edentulous Patients and the Possible Correlation of Serum Serotonin and Apnea-Hypopnea Index
- (2017) Arvind Tripathi et al. Journal of Prosthodontics-Implant Esthetic and Reconstructive Dentistry
- Are people who have a better smell sense, more affected from satiation?
- (2017) Seckin Ulusoy et al. Brazilian Journal of Otorhinolaryngology
- Serotonin increases synaptic activity in olfactory bulb glomeruli
- (2016) Julia Brill et al. JOURNAL OF NEUROPHYSIOLOGY
- Optogenetic Activation of Dorsal Raphe Serotonin Neurons Rapidly Inhibits Spontaneous But Not Odor-Evoked Activity in Olfactory Cortex
- (2016) E. Lottem et al. JOURNAL OF NEUROSCIENCE
- Anxiety- and Depression-Like States Lead to Pronounced Olfactory Deficits and Impaired Adult Neurogenesis in Mice
- (2016) E. Siopi et al. JOURNAL OF NEUROSCIENCE
- The Role of 5-HT3 Receptors in Signaling from Taste Buds to Nerves
- (2015) E. D. Larson et al. JOURNAL OF NEUROSCIENCE
- Buspirone: Back to the Future
- (2015) Robert H. Howland JOURNAL OF PSYCHOSOCIAL NURSING AND MENTAL HEALTH SERVICES
- Immunomodulatory Effects Mediated by Serotonin
- (2015) Rodrigo Arreola et al. Journal of Immunology Research
- The effect of high altitude on olfactory functions
- (2013) Aytuğ Altundağ et al. EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY
- Dysgeusia Successfully Treated With Sertraline
- (2013) Yoshito Mizoguchi et al. JOURNAL OF NEUROPSYCHIATRY AND CLINICAL NEUROSCIENCES
- The TRPM8 channel forms a complex with the 5-HT1B receptor and phospholipase D that amplifies its reversal of pain hypersensitivity
- (2013) Ignacio Vinuela-Fernandez et al. NEUROPHARMACOLOGY
- TRPM8 is the principal mediator of menthol-induced analgesia of acute and inflammatory pain
- (2013) Boyi Liu et al. PAIN
- Defective intestinal amino acid absorption in Ace2 null mice
- (2012) Dustin Singer et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- Serotonergic neuromodulation of peripheral nociceptors
- (2012) Dayna R. Loyd et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- Hypoxia. 3. Hypoxia and neurotransmitter synthesis
- (2011) Ganesh K. Kumar AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- TRPM8 and dyspnea: from the frigid and fascinating past to the cool future?
- (2011) John T Fisher CURRENT OPINION IN PHARMACOLOGY
- Mechanism of acute tryptophan depletion: is it only serotonin?
- (2011) E L van Donkelaar et al. MOLECULAR PSYCHIATRY
- Anti-hyperalgesic effects of anti-serotonergic compounds on serotonin- and capsaicin-evoked thermal hyperalgesia in the rat
- (2011) D.R. Loyd et al. NEUROSCIENCE
- Serotonin increases the functional activity of capsaicin-sensitive rat trigeminal nociceptors via peripheral serotonin receptors
- (2011) Dayna R. Loyd et al. PAIN
- Contributions of central and peripheral chemoreceptors to the ventilatory response to CO2/H+
- (2010) H. V. Forster et al. JOURNAL OF APPLIED PHYSIOLOGY
- Endogenous Peripheral Neuromodulators of the Mammalian Taste Bud
- (2010) Robin Dando JOURNAL OF NEUROPHYSIOLOGY
- The role of the neutral amino acid transporter B0AT1 (SLC6A19) in Hartnup disorder and protein nutrition
- (2009) Stefan Bröer IUBMB LIFE
- Transient Firing of Dorsal Raphe Neurons Encodes Diverse and Specific Sensory, Motor, and Reward Events
- (2009) Sachin P. Ranade et al. JOURNAL OF NEUROPHYSIOLOGY
- How serotonin gates olfactory information flow
- (2009) Guillaume P Dugué et al. NATURE NEUROSCIENCE
- Behavioral choice by presynaptic inhibition of tactile sensory terminals
- (2009) Quentin Gaudry et al. NATURE NEUROSCIENCE
- Serotonergic modulation of odor input to the mammalian olfactory bulb
- (2009) Gabor C Petzold et al. NATURE NEUROSCIENCE
- The TRPV1 ion channel: Implications for respiratory sensation and dyspnea
- (2009) John T. Fisher RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY
- Serotonin and migraine: a reconsideration of the central theory
- (2008) Alessandro Panconesi JOURNAL OF HEADACHE AND PAIN
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