Seladelpar improved measures of pruritus, sleep, and fatigue and decreased serum bile acids in patients with primary biliary cholangitis

Fibrates for itch (FITCH) in fibrosing cholangiopathies: a double blind, randomized, placebo-controlled trial

(2020) Elsemieke de Vries et al.   GASTROENTEROLOGY

Durability of treatment response after 1 year of therapy with seladelpar in patients with primary biliary cholangitis (PBC): final results of an international phase 2 study

(2020) Cynthia Levy et al.   JOURNAL OF HEPATOLOGY

Primary biliary cholangitis

(2020) Ana Lleo et al.   LANCET

MRGPRX4 is a G protein-coupled receptor activated by bile acids that may contribute to cholestatic pruritus

(2019) James Meixiong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Outcomes of Liver Transplant Candidates with Primary Biliary Cholangitis: The Data from the Scientific Registry of Transplant Recipients

(2019) Mehmet Sayiner et al.   DIGESTIVE DISEASES AND SCIENCES

MRGPRX4 is a bile acid receptor for human cholestatic itch

(2019) Huasheng Yu et al.   eLife

Primary biliary cholangitis: pathogenesis and therapeutic opportunities

(2019) Aliya F. Gulamhusein et al.   Nature Reviews Gastroenterology & Hepatology

Scratching the surface of cholestatic itch treatments

(2018) Christopher L. Bowlus   HEPATOLOGY

Rituximab is Ineffective for Treatment of Fatigue in Primary Biliary Cholangitis: A phase-2 Randomised Controlled Trial

(2018) Amardeep Khanna et al.   HEPATOLOGY

Seladelpar’s mechanism of action as a potential treatment for primary biliary cholangitis and non-alcoholic steato-hepatitis

(2018) P. Boudes et al.   JOURNAL OF HEPATOLOGY

Fatigue in chronic liver disease: New insights and therapeutic approaches

(2018) Mark G Swain et al.   LIVER INTERNATIONAL

A Placebo-Controlled Trial of Bezafibrate in Primary Biliary Cholangitis

(2018) Christophe Corpechot et al.   NEW ENGLAND JOURNAL OF MEDICINE

Primary Biliary Cholangitis: 2018 Practice Guidance from the American Association for the Study of Liver Diseases

(2018) Keith D. Lindor et al.   HEPATOLOGY

EASL Clinical Practice Guidelines: The diagnosis and management of patients with primary biliary cholangitis

(2017) Gideon M. Hirschfield et al.   JOURNAL OF HEPATOLOGY

Effect of ileal bile acid transporter inhibitor GSK2330672 on pruritus in primary biliary cholangitis: a double-blind, randomised, placebo-controlled, crossover, phase 2a study

(2017) Vinod S Hegade et al.   LANCET

Itch Assessment with Visual Analogue Scale and Numerical Rating Scale: Determination of Minimal Clinically Important Difference in Chronic Itch

(2016) A Reich et al.   ACTA DERMATO-VENEREOLOGICA

A Placebo-Controlled Trial of Obeticholic Acid in Primary Biliary Cholangitis

(2016) Frederik Nevens et al.   NEW ENGLAND JOURNAL OF MEDICINE

Serum Autotaxin is a Marker of the Severity of Liver Injury and Overall Survival in Patients with Cholestatic Liver Diseases

(2016) Ewa Wunsch et al.   Scientific Reports

The safety and efficacy of nasobiliary drainage in the treatment of refractory cholestatic pruritus: a multicentre European study

(2015) V. S. Hegade et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Visual Analogue Scale: Evaluation of the Instrument for the Assess­ment of Pruritus

(2013) A Reich et al.   ACTA DERMATO-VENEREOLOGICA

Pruritus in cholestasis: Facts and fiction

(2013) Ulrich Beuers et al.   HEPATOLOGY

The impact of liver transplantation on the phenotype of primary biliary cirrhosis patients in the UK-PBC cohort

(2013) Greta Pells et al.   JOURNAL OF HEPATOLOGY

Sex and Age Are Determinants of the Clinical Phenotype of Primary Biliary Cirrhosis and Response to Ursodeoxycholic Acid

(2012) Marco Carbone et al.   GASTROENTEROLOGY

MBX-8025, A Novel Peroxisome Proliferator Receptor-δ Agonist: Lipid and Other Metabolic Effects in Dyslipidemic Overweight Patients Treated with and without Atorvastatin

(2011) Harold E. Bays et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

The 5-D itch scale: a new measure of pruritus

(2009) S. Elman et al.   BRITISH JOURNAL OF DERMATOLOGY

Itch in Primary Biliary Cirrhosis: A Patients’ Perspective

(2008) E Rishe et al.   ACTA DERMATO-VENEREOLOGICA