Mouse bone marrow derived mesenchymal stem cells-secreted exosomal microRNA-125b-5p suppresses atherosclerotic plaque formation via inhibiting Map4k4

Clonally expanding smooth muscle cells promote atherosclerosis by escaping efferocytosis and activating the complement cascade

(2020) Ying Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Platelet‐conditioned media induces an anti‐inflammatory macrophage phenotype through EP4

(2020) Sean P. Heffron et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

miR-185 silencing promotes the progression of atherosclerosis via targeting stromal interaction molecule 1

(2019) Ming Fang et al.   CELL CYCLE

Exosomes derived from mesenchymal stem cells attenuate the progression of atherosclerosis in ApoE−/- mice via miR-let7 mediated infiltration and polarization of M2 macrophage

(2019) Jiangbing Li et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Propranolol suppresses infantile hemangioma cell proliferation and promotes apoptosis by upregulating miR-125b expression

(2019) Jiajia Huang et al.   ANTI-CANCER DRUGS

MicroRNA-99a-5p alleviates atherosclerosis via regulating Homeobox A1

(2019) Zhiyang Han et al.   LIFE SCIENCES

MiR-125b-5p and miR-181b-5p inhibit keratinocyte proliferation in skin by targeting Akt3

(2019) Yunpeng Zheng et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Exosomes derived from liver cancer cells reprogram biological behaviors of LO2 cells by transferring Linc-ROR

(2019) Xiaoqin He et al.   GENE

Hyperlipidemia induces typical atherosclerosis development in Ldlr and Apoe deficient rats

(2018) Yongliang Zhao et al.   ATHEROSCLEROSIS

Insulin resistance adipocyte-derived exosomes aggravate atherosclerosis by increasing vasa vasorum angiogenesis in diabetic ApoE −/− mice

(2018) Feng Wang et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Downregulated miR-98-5p promotes PDAC proliferation and metastasis by reversely regulating MAP4K4

(2018) Yue Fu et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Treatment target re-classification of subjects comparing estimation of low-density lipoprotein cholesterol by the Friedewald equation and direct measurement of LDL-cholesterol

(2018) Anders Larsson et al.   UPSALA JOURNAL OF MEDICAL SCIENCES

MicroRNA-125b mimic inhibits ischemia reperfusion-induced neuroinflammation and aberrant p53 apoptotic signalling activation through targeting TP53INP1

(2018) Xiao-Qian Li et al.   BRAIN BEHAVIOR AND IMMUNITY

MiR-188-3p upregulation results in the inhibition of macrophage proinflammatory activities and atherosclerosis in ApoE-deficient mice

(2018) Xian-Feng Zhang et al.   THROMBOSIS RESEARCH

Exosome-derived miRNAs as predictive biomarkers for diffuse large B-cell lymphoma chemotherapy resistance

(2018) Yuhua Feng et al.   Epigenomics

Serum-Free Medium Enhances the Immunosuppressive and Antifibrotic Abilities of Mesenchymal Stem Cells Utilized in Experimental Renal Fibrosis

(2018) Ken Yoshida et al.   Stem Cells Translational Medicine

Bitter melon (Momordica charantia) attenuates atherosclerosis in apo-E knock-out mice possibly through reducing triglyceride and anti-inflammation

(2018) Yanmei Zeng et al.   Lipids in Health and Disease

Exosomes derived from mesenchymal stem cells attenuate inflammation and demyelination of the central nervous system in EAE rats by regulating the polarization of microglia

(2018) Zijian Li et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Thrombin-activated platelet-derived exosomes regulate endothelial cell expression of ICAM-1 via microRNA-223 during the thrombosis-inflammation response

(2017) Jiannan Li et al.   THROMBOSIS RESEARCH

Exosomal lncRNA GAS5 regulates the apoptosis of macrophages and vascular endothelial cells in atherosclerosis

(2017) Lei Chen et al.   PLoS One

MicroRNA-125b-5p attenuates lipopolysaccharide-induced monocyte chemoattractant protein-1 production by targeting inhibiting LACTB in THP-1 macrophages

(2016) Jing-Bo Lu et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Irgm1 promotes M1 but not M2 macrophage polarization in atherosclerosis pathogenesis and development

(2016) Shaohong Fang et al.   ATHEROSCLEROSIS

MiR-125b regulates SFRP5 expression to promote growth and activation of cardiac fibroblasts

(2016) Zi-dong Bie et al.   CELL BIOLOGY INTERNATIONAL

Exosomes derived from mature dendritic cells increase endothelial inflammation and atherosclerosisviamembrane TNF-α mediated NF-κB pathway

(2016) Wei Gao et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

MiR-194, commonly repressed in colorectal cancer, suppresses tumor growth by regulating the MAP4K4/c-Jun/MDM2 signaling pathway

(2015) Bo Wang et al.   CELL CYCLE

Endothelial and smooth muscle cell transformation in atherosclerosis

(2015) Ka Hou Lao et al.   CURRENT OPINION IN LIPIDOLOGY

Endothelial protein kinase MAP4K4 promotes vascular inflammation and atherosclerosis

(2015) Rachel J. Roth Flach et al.   Nature Communications

Skin-Derived Mesenchymal Stem Cells Alleviate Atherosclerosis via Modulating Macrophage Function

(2015) Qun Li et al.   Stem Cells Translational Medicine

MicroRNA-125b is involved in atherosclerosis obliterans in vitro by targeting podocalyxin

(2015) XIAOBING LI et al.   Molecular Medicine Reports

Cellular MicroRNA Let-7a Suppresses KSHV Replication through Targeting MAP4K4 Signaling Pathways

(2015) Xiaohua Tan et al.   PLoS One

Identification of hypo- and hypermethylated genes related to atherosclerosis by a genome-wide analysis of DNA methylation

(2014) YOSHIJI YAMADA et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Mesenchymal Stem Cells Ameliorate Atherosclerotic Lesions via Restoring Endothelial Function

(2014) Yu-Ling Lin et al.   Stem Cells Translational Medicine

miRNA-141, Downregulated in Pancreatic Cancer, Inhibits Cell Proliferation and Invasion by Directly Targeting MAP4K4

(2013) Gang Zhao et al.   MOLECULAR CANCER THERAPEUTICS

miR-125b Regulates Calcification of Vascular Smooth Muscle Cells

(2011) Claudia Goettsch et al.   AMERICAN JOURNAL OF PATHOLOGY

Orally delivered siRNA targeting macrophage Map4k4 suppresses systemic inflammation

(2009) Myriam Aouadi et al.   NATURE