Improving prediction accuracy in acute myeloid leukaemia: micro-environment, immune and metabolic models

Characterization of Immune Dysfunction and Identification of Prognostic Immune-Related Risk Factors in Acute Myeloid Leukemia

(2020) Lu Tang et al.   CLINICAL CANCER RESEARCH

RNA splicing alterations induce a cellular stress response associated with poor prognosis in Acute Myeloid Leukemia

(2020) Govardhan Anande et al.   CLINICAL CANCER RESEARCH

Metabolomics analysis identifies lysine and taurine as candidate prognostic biomarkers for AML-M2 patients

(2020) Xuan Zhou et al.   INTERNATIONAL JOURNAL OF HEMATOLOGY

Serum levels of selected cytokines and soluble adhesion molecules in acute myeloid leukemia: Soluble receptor for interleukin-2 predicts overall survival

(2020) Tomas Kupsa et al.   CYTOKINE

Expression patterns of immune checkpoints in acute myeloid leukemia

(2020) Cunte Chen et al.   Journal of Hematology & Oncology

Systematic Construction and Validation of a Metabolic Risk Model for Prognostic Prediction in Acute Myelogenous Leukemia

(2020) Yun Wang et al.   Frontiers in Oncology

Ivosidenib or enasidenib combined with intensive chemotherapy in patients with newly diagnosed AML: a phase 1 study

(2020) Eytan M. Stein et al.   BLOOD

Effects of Alternative Splicing Events on Acute Myeloid Leukemia

(2020) Si-Liang Chen et al.   DNA AND CELL BIOLOGY

Precision medicine treatment in acute myeloid leukemia using prospective genomic profiling: feasibility and preliminary efficacy of the Beat AML Master Trial

(2020) Amy Burd et al.   NATURE MEDICINE

Comprehensive Analysis of Prognostic Markers for Acute Myeloid Leukemia Based on Four Metabolic Genes

(2020) Yuanyuan Zhang et al.   Frontiers in Oncology

An Immune Risk Score Predicts Survival of Patients with Acute Myeloid Leukemia Receiving Chemotherapy

(2020) Yun Wang et al.   CLINICAL CANCER RESEARCH

A new cytokine‐based dynamic stratification during induction is highly predictive of survivals in acute myeloid leukemia

(2020) Pierre Peterlin et al.   Cancer Medicine

Identification of an Immune-Related Gene Signature Based on Immunogenomic Landscape Analysis to Predict the Prognosis of Adult Acute Myeloid Leukemia Patients

(2020) Ruiqi Zhu et al.   Frontiers in Oncology

Eomes+T-betlow CD8+ T cells are functionally impaired and are associated with poor clinical outcome in patients with acute myeloid leukemia (AML)

(2019) Bei Jia et al.   CANCER RESEARCH

Prognostic index for patients with relapsed or refractory acute myeloid leukemia who underwent hematopoietic cell transplantation: a KSGCT multicenter analysis

(2019) Takayoshi Tachibana et al.   LEUKEMIA

Gut Microbiome Signatures Are Predictive of Infectious Risk Following Induction Therapy for Acute Myeloid Leukemia

(2019) Jessica R Galloway-Peña et al.   CLINICAL INFECTIOUS DISEASES

Comprehensive prognostic scoring systems could improve the prognosis of adult acute myeloid leukemia patients

(2019) Fan Zhou et al.   INTERNATIONAL JOURNAL OF HEMATOLOGY

Immune checkpoints PVR and PVRL2 are prognostic markers in AML and their blockade represents a new therapeutic option

(2018) Hauke Stamm et al.   ONCOGENE

Acute Myeloid Leukemia Cells Express ICOS Ligand to Promote the Expansion of Regulatory T Cells

(2018) Yixiang Han et al.   Frontiers in Immunology

Clinical implications of genome-wide DNA methylation studies in acute myeloid leukemia

(2017) Yan Li et al.   Journal of Hematology & Oncology

How good are we at predicting the fate of someone with acute myeloid leukaemia?

(2017) E Estey et al.   LEUKEMIA

Measurable residual disease testing in acute myeloid leukaemia

(2017) C S Hourigan et al.   LEUKEMIA

Precision oncology for acute myeloid leukemia using a knowledge bank approach

(2017) Moritz Gerstung et al.   NATURE GENETICS

T-Cell Immunoglobulin and ITIM Domain (TIGIT) Associates with CD8+ T-Cell Exhaustion and Poor Clinical Outcome in AML Patients

(2016) Y. Kong et al.   CLINICAL CANCER RESEARCH

Effect of measurable (‘minimal’) residual disease (MRD) information on prediction of relapse and survival in adult acute myeloid leukemia

(2016) M Othus et al.   LEUKEMIA

PD-L1 (CD274) promoter methylation predicts survival in patients with acute myeloid leukemia

(2016) D Goltz et al.   LEUKEMIA

Isocitrate dehydrogenase mutations in myeloid malignancies

(2016) B C Medeiros et al.   LEUKEMIA

A 17-gene stemness score for rapid determination of risk in acute leukaemia

(2016) Stanley W. K. Ng et al.   NATURE

Genomic Classification and Prognosis in Acute Myeloid Leukemia

(2016) Elli Papaemmanuil et al.   NEW ENGLAND JOURNAL OF MEDICINE

Acute myeloid leukaemia

(2016) Asim Khwaja et al.   Nature Reviews Disease Primers

A distinct glucose metabolism signature of acute myeloid leukemia with prognostic value

(2014) W.-L. Chen et al.   BLOOD

Isocitrate dehydrogenase (IDH)2 R140Q mutation induces myeloid and lymphoid neoplasms in mice

(2014) E Mylonas et al.   LEUKEMIA

Cytokine profiles in acute myeloid leukemia patients at diagnosis: Survival is inversely correlated with IL-6 and directly correlated with IL-10 levels

(2013) Beatriz Sanchez-Correa et al.   CYTOKINE

Mutant DNMT3A: a marker of poor prognosis in acute myeloid leukemia

(2012) A. F. T. Ribeiro et al.   BLOOD

Natural killer cell immune escape in acute myeloid leukemia

(2012) E Lion et al.   LEUKEMIA

Elevated frequencies of CD4+CD25+CD127lo regulatory T cells is associated to poor prognosis in patients with acute myeloid leukemia

(2010) Zhang Shenghui et al.   INTERNATIONAL JOURNAL OF CANCER

Contribution of bone microenvironment to leukemogenesis and leukemia progression

(2009) F Ayala et al.   LEUKEMIA

The prognostic significance of cytokine levels in newly diagnosed acute myeloid leukemia and high-risk myelodysplastic syndromes

(2008) Apostolia Maria Tsimberidou et al.   CANCER