Roles of aldo-keto reductases 1B10 and 1C3 and ATP-binding cassette transporter in docetaxel tolerance

Pharmacokinetic interactions of breast cancer chemotherapeutics with human doxorubicin reductases

(2015) Jakub Hofman et al.   BIOCHEMICAL PHARMACOLOGY

On the role of 4-hydroxynonenal in health and disease

(2015) Miklós Csala et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Aldo-keto reductase 1C3 (AKR1C3) is associated with the doxorubicin resistance in human breast cancer via PTEN Loss

(2015) Ting Zhong et al.   BIOMEDICINE & PHARMACOTHERAPY

Acquisition of doxorubicin resistance facilitates migrating and invasive potentials of gastric cancer MKN45 cells through up-regulating aldo–keto reductase 1B10

(2015) Yoshifumi Morikawa et al.   CHEMICO-BIOLOGICAL INTERACTIONS

miR-138-Mediated Regulation of KINDLIN-2 Expression Modulates Sensitivity to Chemotherapeutics

(2015) K. Sossey-Alaoui et al.   MOLECULAR CANCER RESEARCH

Nanoways to overcome docetaxel resistance in prostate cancer

(2014) Aditya Ganju et al.   DRUG RESISTANCE UPDATES

Regulation of SOD2 and β-arrestin1 by interleukin-6 contributes to the increase of IGF-1R expression in docetaxel resistant prostate cancer cells

(2014) Denglu Zhang et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Nitric oxide confers cisplatin resistance in human lung cancer cells through upregulation of aldo-keto reductase 1B10 and proteasome

(2014) T. Matsunaga et al.   FREE RADICAL RESEARCH

Nrf2 Upregulates ATP Binding Cassette Transporter Expression and Activity at the Blood-Brain and Blood-Spinal Cord Barriers

(2014) X. Wang et al.   JOURNAL OF NEUROSCIENCE

Anthracycline resistance mediated by reductive metabolism in cancer cells: The role of aldo-keto reductase 1C3

(2014) Jakub Hofman et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Exposure to 9,10-phenanthrenequinone accelerates malignant progression of lung cancer cells through up-regulation of aldo-keto reductase 1B10

(2014) Toshiyuki Matsunaga et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Microtubules and Their Role in Cellular Stress in Cancer

(2014) Amelia L. Parker et al.   Frontiers in Oncology

A randomised multicentre phase II study with cisplatin/docetaxel vs oxaliplatin/docetaxel as first-line therapy in patients with advanced or metastatic non-small cell lung cancer

(2013) A Atmaca et al.   BRITISH JOURNAL OF CANCER

AKR1C3 as a target in castrate resistant prostate cancer

(2013) Adegoke O. Adeniji et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Inhibition of ABCB1 Expression Overcomes Acquired Docetaxel Resistance in Prostate Cancer

(2013) Y. Zhu et al.   MOLECULAR CANCER THERAPEUTICS

Role of aldo-keto reductases and other doxorubicin pharmacokinetic genes in doxorubicin resistance, DNA binding, and subcellular localization

(2012) Allan D Heibein et al.   BMC CANCER

Taxane resistance in breast cancer: Mechanisms, predictive biomarkers and circumvention strategies

(2012) S. Murray et al.   CANCER TREATMENT REVIEWS

Pathophysiological roles of aldo–keto reductases (AKR1C1 and AKR1C3) in development of cisplatin resistance in human colon cancers

(2012) Toshiyuki Matsunaga et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Involvement of the aldo–keto reductase, AKR1B10, in mitomycin-c resistance through reactive oxygen species-dependent mechanisms

(2011) Toshiyuki Matsunaga et al.   ANTI-CANCER DRUGS

Human aldo–keto reductases 1B1 and 1B10: A comparative study on their enzyme activity toward electrophilic carbonyl compounds

(2011) Yi Shen et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Design, synthesis and evaluation of caffeic acid phenethyl ester-based inhibitors targeting a selectivity pocket in the active site of human aldo–keto reductase 1B10

(2011) Midori Soda et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Selective Inhibition of the Tumor Marker Aldo-keto Reductase Family Member 1B10 by Oleanolic Acid

(2011) Mayuko Takemura et al.   JOURNAL OF NATURAL PRODUCTS

Roles of rat and human aldo–keto reductases in metabolism of farnesol and geranylgeraniol

(2010) Satoshi Endo et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Kinetic studies of AKR1B10, human aldose reductase-like protein: Endogenous substrates and inhibition by steroids

(2009) Satoshi Endo et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Characterization of the cancer chemopreventive NRF2-dependent gene battery in human keratinocytes: demonstration that the KEAP1–NRF2 pathway, and not the BACH1–NRF2 pathway, controls cytoprotection against electrophiles as well as redox-cycling compounds

(2009) A.Kenneth MacLeod et al.   CARCINOGENESIS

Novel Taxane Formulations and Microtubule-Binding Agents in Non–Small-Cell Lung Cancer

(2009) Martin J. Edelman   Clinical Lung Cancer

Identification and expression analysis of the aldo–ketoreductase1-B10 gene in primary malignant liver tumours

(2009) Stefan Heringlake et al.   JOURNAL OF HEPATOLOGY

Structure-Guided Design, Synthesis, and Evaluation of Salicylic Acid-Based Inhibitors Targeting a Selectivity Pocket in the Active Site of Human 20α-Hydroxysteroid Dehydrogenase (AKR1C1)

(2009) Ossama El-Kabbani et al.   JOURNAL OF MEDICINAL CHEMISTRY

Induction of 1C aldoketoreductases and other drug dose-dependent genes upon acquisition of anthracycline resistance

(2009) Zachary W. Veitch et al.   Pharmacogenetics and Genomics

The Gene Expression Profiles of Medulloblastoma Cell Lines Resistant to Preactivated Cyclophosphamide

(2008) M. Bacolod et al.   CURRENT CANCER DRUG TARGETS

The Aldo-Keto Reductase Superfamily and its Role in Drug Metabolism and Detoxification

(2008) Oleg A. Barski et al.   DRUG METABOLISM REVIEWS