Measurement of complex DNA damage induction and repair in human cellular systems after exposure to ionizing radiations of varying linear energy transfer (LET)

Identification of DNA double strand breaks at chromosome boundaries along the track of particle irradiation

(2016) Atsuko Niimi et al.   GENES CHROMOSOMES & CANCER

Gamma-irradiated quiescent cells repair directly induced double-strand breaks but accumulate persistent double-strand breaks during subsequent DNA replication

(2016) Yusuke Minakawa et al.   GENES TO CELLS

Unraveling the mechanisms of extreme radioresistance in prokaryotes: Lessons from nature

(2016) Athanasia Pavlopoulou et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH

Chromosome thripsis by DNA double strand break clusters causes enhanced cell lethality, chromosomal translocations and 53BP1-recruitment

(2016) Agnes Schipler et al.   NUCLEIC ACIDS RESEARCH

Superresolution intrinsic fluorescence imaging of chromatin utilizing native, unmodified nucleic acids for contrast

(2016) Biqin Dong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Non-DSB clustered DNA lesions. Does theory colocalize with the experiment?

(2016) Zacharenia Nikitaki et al.   RADIATION PHYSICS AND CHEMISTRY

Radiation track, DNA damage and response—a review

(2016) H Nikjoo et al.   REPORTS ON PROGRESS IN PHYSICS

Simultaneous multiview capture and fusion improves spatial resolution in wide-field and light-sheet microscopy

(2016) Yicong Wu et al.   Optica

Novel Biological Approaches for Testing the Contributions of Single DSBs and DSB Clusters to the Biological Effects of High LET Radiation

(2016) Veronika Mladenova et al.   Frontiers in Oncology

Multiscale approach predictions for biological outcomes in ion-beam cancer therapy

(2016) Alexey Verkhovtsev et al.   Scientific Reports

DNA damage foci: Meaning and significance

(2015) Kai Rothkamm et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

Linking Gamma-H2AX Foci and Cancer in Rat Skin Exposed to Heavy Ions and Electron Radiation

(2015) Fredric J. Burns et al.   HEALTH PHYSICS

Chemical proteomics reveals a γH2AX-53BP1 interaction in the DNA damage response

(2015) Ralph E Kleiner et al.   Nature Chemical Biology

The DNA damage response and immune signaling alliance: Is it good or bad? Nature decides when and where

(2015) Ioannis S. Pateras et al.   PHARMACOLOGY & THERAPEUTICS

Induction and Repair of DNA DSB as Revealed by H2AX Phosphorylation Foci in Human Fibroblasts Exposed to Low- and High-LET Radiation: Relationship with Early and Delayed Reproductive Cell Death

(2015) F. Antonelli et al.   RADIATION RESEARCH

Spectrum of Radiation-Induced Clustered Non-DSB Damage – A Monte Carlo Track Structure Modeling and Calculations

(2015) Ritsuko Watanabe et al.   RADIATION RESEARCH

Stress-induced DNA damage biomarkers: applications and limitations

(2015) Zacharenia Nikitaki et al.   Frontiers in Chemistry

New challenges in high-energy particle radiobiology

(2013) M Durante   BRITISH JOURNAL OF RADIOLOGY

Statistical analysis of kinetics, distribution and co-localisation of DNA repair foci in irradiated cells: Cell cycle effect and implications for prediction of radiosensitivity

(2013) Olga A. Martin et al.   DNA REPAIR

DNA double-strand-break complexity levels and their possible contributions to the probability for error-prone processing and repair pathway choice

(2013) A. Schipler et al.   NUCLEIC ACIDS RESEARCH

Visualisation of γH2AX Foci Caused by Heavy Ion Particle Traversal; Distinction between Core Track versus Non-Track Damage

(2013) Nakako Izumi Nakajima et al.   PLoS One

Induction and Repair of Clustered DNA Lesions: What Do We Know So Far?

(2013) Alexandros G. Georgakilas et al.   RADIATION RESEARCH

Repair of DNA damage induced by accelerated heavy ions-A mini review

(2011) Ryuichi Okayasu   INTERNATIONAL JOURNAL OF CANCER

Physical and biophysical properties of proton tracks of energies 1 keV to 300 MeV in water

(2011) Thiansin Liamsuwan et al.   INTERNATIONAL JOURNAL OF RADIATION BIOLOGY

γH2AX foci as a measure of DNA damage: A computational approach to automatic analysis

(2011) Alesia N. Ivashkevich et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Track structures, DNA targets and radiation effects in the biophysical Monte Carlo simulation code PARTRAC

(2011) Werner Friedland et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Unrepaired clustered DNA lesions induce chromosome breakage in human cells

(2011) A. Asaithamby et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Evidence for formation of DNA repair centers and dose-response nonlinearity in human cells

(2011) T. Neumaier et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

DNA-PKcs deficiency leads to persistence of oxidatively induced clustered DNA lesions in human tumor cells

(2010) Prakash Peddi et al.   FREE RADICAL BIOLOGY AND MEDICINE

A database of frequency distributions of energy depositions in small-size targets by electrons and ions

(2010) H. Nikjoo et al.   RADIATION PROTECTION DOSIMETRY

Hierarchy of lesion processing governs the repair, double-strand break formation and mutability of three-lesion clustered DNA damage

(2009) Laura J. Eccles et al.   NUCLEIC ACIDS RESEARCH

Cellular responses to DNA double-strand breaks after low-dose γ-irradiation

(2009) Aroumougame Asaithamby et al.   NUCLEIC ACIDS RESEARCH

Formation of Clustered DNA Damage after High-LET Irradiation: A Review

(2008) Megumi HADA et al.   JOURNAL OF RADIATION RESEARCH

 -H2AX in recognition and signaling of DNA double-strand breaks in the context of chromatin

(2008) A. Kinner et al.   NUCLEIC ACIDS RESEARCH

Induction and processing of complex DNA damage in human breast cancer cells MCF-7 and nonmalignant MCF-10A cells

(2007) Dave C. Francisco et al.   FREE RADICAL BIOLOGY AND MEDICINE

Processing of DNA damage clusters in human cells: current status of knowledge

(2007) Alexandros G. Georgakilas   Molecular BioSystems