Development and Evaluation of an Ebola Virus Glycoprotein Mucin-Like Domain Replacement System as a New Dendritic Cell-Targeting Vaccine Approach against HIV-1

Incorporation of Ebola glycoprotein into HIV particles facilitates dendritic cell and macrophage targeting and enhances HIV-specific immune responses

(2019) Zhujun Ao et al.   PLoS One

Dendritic Cells/Macrophages-Targeting Feature of Ebola Glycoprotein and its Potential as Immunological Facilitator for Antiviral Vaccine Approach

(2019) Titus Abiola Olukitibi et al.   Microorganisms

Advances in HIV-1 Vaccine Development

(2018) Yong Gao et al.   Viruses-Basel

The development of HIV vaccines targeting gp41 membrane-proximal external region (MPER): challenges and prospects

(2018) Huan Liu et al.   Protein & Cell

HIV Env conserved element DNA vaccine alters immunodominance in macaques

(2017) Xintao Hu et al.   Human Vaccines & Immunotherapeutics

Ebola Virus Glycoprotein Induces an Innate Immune Response In vivo via TLR4

(2017) Chih-Yun Lai et al.   Frontiers in Microbiology

A universal mammalian vaccine cell line substrate

(2017) Jackelyn Murray et al.   PLoS One

Characterization of the single cycle replication of HIV-1 expressing Gaussia luciferase in human PBMCs, macrophages, and in CD4+ T cell-grafted nude mouse

(2016) Zhujun Ao et al.   JOURNAL OF VIROLOGICAL METHODS

Phase 1 Trials of rVSV Ebola Vaccine in Africa and Europe

(2016) Selidji T. Agnandji et al.   NEW ENGLAND JOURNAL OF MEDICINE

The effect of dose on the safety and immunogenicity of the VSV Ebola candidate vaccine: a randomised double-blind, placebo-controlled phase 1/2 trial

(2015) Angela Huttner et al.   LANCET INFECTIOUS DISEASES

VSV-EBOV rapidly protects macaques against infection with the 2014/15 Ebola virus outbreak strain

(2015) A. Marzi et al.   SCIENCE

Virus-Like Particles Activate Type I Interferon Pathways to Facilitate Post-Exposure Protection against Ebola Virus Infection

(2015) Natarajan Ayithan et al.   PLoS One

Spatial Localization of the Ebola Virus Glycoprotein Mucin-Like Domain Determined by Cryo-Electron Tomography

(2014) E. E. H. Tran et al.   JOURNAL OF VIROLOGY

Comprehensive Functional Analysis of N-Linked Glycans on Ebola Virus GP1

(2014) N. J. Lennemann et al.   mBio

Shed GP of Ebola Virus Triggers Immune Activation and Increased Vascular Permeability

(2014) Beatriz Escudero-Pérez et al.   PLoS Pathogens

Vaccine-induced Human Antibodies Specific for the Third Variable Region of HIV-1 gp120 Impose Immune Pressure on Infecting Viruses

(2014) Susan Zolla-Pazner et al.   EBioMedicine

Ebola Virus-Like Particles Stimulate Type I Interferons and Proinflammatory Cytokine Expression Through the Toll-Like Receptor and Interferon Signaling Pathways

(2013) Natarajan Ayithan et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Ebola Virus Exploits a Monocyte Differentiation Program To Promote Its Entry

(2013) O. Martinez et al.   JOURNAL OF VIROLOGY

A Dendritic Cell-Based Vaccine Elicits T Cell Responses Associated with Control of HIV-1 Replication

(2013) F. Garcia et al.   Science Translational Medicine

Vesicular Stomatitis Virus-Based Vaccines Protect Nonhuman Primates against Bundibugyo ebolavirus

(2013) Chad E. Mire et al.   PLoS Neglected Tropical Diseases

The role of antigen-presenting cells in filoviral hemorrhagic fever: Gaps in current knowledge

(2012) Osvaldo Martinez et al.   ANTIVIRAL RESEARCH

A DNA-Based Candidate HIV Vaccine Delivered viaIn VivoElectroporation Induces CD4 Responses toward the α4β7-Binding V2 Loop of HIV gp120 in Healthy Volunteers

(2012) Jakub Kopycinski et al.   Clinical and Vaccine Immunology

Humoral innate immune response and disease

(2012) Stephanie N. Shishido et al.   CLINICAL IMMUNOLOGY

Broad neutralization by a combination of antibodies recognizing the CD4 binding site and a new conformational epitope on the HIV-1 envelope protein

(2012) Florian Klein et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Immune-Correlates Analysis of an HIV-1 Vaccine Efficacy Trial

(2012) Barton F. Haynes et al.   NEW ENGLAND JOURNAL OF MEDICINE

A Therapeutic Dendritic Cell-Based Vaccine for HIV-1 Infection

(2011) Felipe García et al.   JOURNAL OF INFECTIOUS DISEASES

Memory B Cell Antibodies to HIV-1 gp140 Cloned from Individuals Infected with Clade A and B Viruses

(2011) Hugo Mouquet et al.   PLoS One

Ebola Virion Attachment and Entry into Human Macrophages Profoundly Effects Early Cellular Gene Expression

(2011) Victoria Wahl-Jensen et al.   PLoS Neglected Tropical Diseases

Anti-V3 Monoclonal Antibodies Display Broad Neutralizing Activities against Multiple HIV-1 Subtypes

(2010) Catarina E. Hioe et al.   PLoS One

Ebolavirus Glycoprotein GP Masks both Its Own Epitopes and the Presence of Cellular Surface Proteins

(2009) O. Reynard et al.   JOURNAL OF VIROLOGY

Interaction between Ebola Virus Glycoprotein and Host Toll-Like Receptor 4 Leads to Induction of Proinflammatory Cytokines and SOCS1

(2009) A. Okumura et al.   JOURNAL OF VIROLOGY

Single-Injection Vaccine Protects Nonhuman Primates against Infection with Marburg Virus and Three Species of Ebola Virus

(2009) T. W. Geisbert et al.   JOURNAL OF VIROLOGY

Vaccination with ALVAC and AIDSVAX to Prevent HIV-1 Infection in Thailand

(2009) Supachai Rerks-Ngarm et al.   NEW ENGLAND JOURNAL OF MEDICINE

An HIV-1 clade C DNA prime, NYVAC boost vaccine regimen induces reliable, polyfunctional, and long-lasting T cell responses

(2008) Alexandre Harari et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Structure of the Ebola virus glycoprotein bound to an antibody from a human survivor

(2008) Jeffrey E. Lee et al.   NATURE