Virus-Like Particles Activate Type I Interferon Pathways to Facilitate Post-Exposure Protection against Ebola Virus Infection

Vaccination with recombinant adenoviruses expressing Ebola virus glycoprotein elicits protection in the interferon alpha/beta receptor knock-out mouse

(2014) Lyn M. O'Brien et al.   VIROLOGY

Deficient IFN Signaling by Myeloid Cells Leads to MAVS-Dependent Virus-Induced Sepsis

(2014) Amelia K. Pinto et al.   PLoS Pathogens

Essential role of the IRF8-KLF4 transcription factor cascade in murine monocyte differentiation

(2013) D. Kurotaki et al.   BLOOD

Overcoming NS1-Mediated Immune Antagonism Involves Both Interferon-Dependent and Independent Mechanisms

(2013) Juilee Thakar et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Ebola Virus-Like Particles Stimulate Type I Interferons and Proinflammatory Cytokine Expression Through the Toll-Like Receptor and Interferon Signaling Pathways

(2013) Natarajan Ayithan et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Current ebola vaccines

(2012) Thomas Hoenen et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

The Small Ubiquitin-like Modifier-Deconjugating Enzyme Sentrin-Specific Peptidase 1 Switches IFN Regulatory Factor 8 from a Repressor to an Activator during Macrophage Activation

(2012) T.-H. Chang et al.   JOURNAL OF IMMUNOLOGY

Interferon-β Therapy Prolongs Survival in Rhesus Macaque Models of Ebola and Marburg Hemorrhagic Fever

(2012) Lauren M. Smith et al.   JOURNAL OF INFECTIOUS DISEASES

Virus-like particles as a highly efficient vaccine platform: Diversity of targets and production systems and advances in clinical development

(2012) Natasha Kushnir et al.   VACCINE

Mouse Models for Filovirus Infections

(2012) Steven B. Bradfute et al.   Viruses-Basel

Ebolavirus vaccines for humans and apes

(2012) Hugues Fausther-Bovendo et al.   Current Opinion in Virology

Type I Interferon Inhibits Interleukin-1 Production and Inflammasome Activation

(2011) Greta Guarda et al.   IMMUNITY

Filovirus Infection of STAT-1 Knockout Mice

(2011) JoLynne Raymond et al.   JOURNAL OF INFECTIOUS DISEASES

Lethality and pathogenesis of airborne infection with filoviruses in A129  /  -/- interferon receptor-deficient mice

(2011) M. S. Lever et al.   JOURNAL OF MEDICAL MICROBIOLOGY

IRF8Mutations and Human Dendritic-Cell Immunodeficiency

(2011) Sophie Hambleton et al.   NEW ENGLAND JOURNAL OF MEDICINE

Intracellular Events and Cell Fate in Filovirus Infection

(2011) Judith Olejnik et al.   Viruses-Basel

Correlates of Immunity to Filovirus Infection

(2011) Steven Bradfute et al.   Viruses-Basel

Distinct Patterns of IFITM-Mediated Restriction of Filoviruses, SARS Coronavirus, and Influenza A Virus

(2011) I-Chueh Huang et al.   PLoS Pathogens

Tripartite-Motif Protein 30 Negatively Regulates NLRP3 Inflammasome Activation by Modulating Reactive Oxygen Species Production

(2010) Y. Hu et al.   JOURNAL OF IMMUNOLOGY

Human Fatal Zaire Ebola Virus Infection Is Associated with an Aberrant Innate Immunity and with Massive Lymphocyte Apoptosis

(2010) Nadia Wauquier et al.   PLoS Neglected Tropical Diseases

Gene Disruption Study Reveals a Nonredundant Role for TRIM21/Ro52 in NF- B-Dependent Cytokine Expression in Fibroblasts

(2009) R. Yoshimi et al.   JOURNAL OF IMMUNOLOGY

Evasion of Interferon Responses by Ebola and Marburg Viruses

(2009) Christopher F. Basler et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Ebola Zaire Virus Blocks Type I Interferon Production by Exploiting the Host SUMO Modification Machinery

(2009) Tsung-Hsien Chang et al.   PLoS Pathogens

The IRF Family Transcription Factors in Immunity and Oncogenesis

(2008) Tomohiko Tamura et al.   Annual Review of Immunology

Protection against filovirus infection: virus-like particle vaccines

(2008) Chinglai Yang et al.   Expert Review of Vaccines

Inhibition of IRF-3 Activation by VP35 Is Critical for the High Level of Virulence of Ebola Virus

(2008) A. L. Hartman et al.   JOURNAL OF VIROLOGY

Whole-Genome Expression Profiling Reveals That Inhibition of Host Innate Immune Response Pathways by Ebola Virus Can Be Reversed by a Single Amino Acid Change in the VP35 Protein

(2008) A. L. Hartman et al.   JOURNAL OF VIROLOGY

TRIM30α negatively regulates TLR-mediated NF-κB activation by targeting TAB2 and TAB3 for degradation

(2008) Mude Shi et al.   NATURE IMMUNOLOGY