SARS-CoV-2 Spike Protein Induces Paracrine Senescence and Leukocyte Adhesion in Endothelial Cells

Oxidative Stress Status in COVID-19 Patients Hospitalized in Intensive Care Unit for Severe Pneumonia. A Pilot Study

(2021) Joël Pincemail et al.   Antioxidants

BET inhibition blocks inflammation-induced cardiac dysfunction and SARS-CoV-2 infection

(2021) Richard J. Mills et al.   CELL

Role of epithelial-endothelial cell interaction in the pathogenesis of SARS-CoV-2 infection

(2021) Kenrie Pui-Yan Hui et al.   CLINICAL INFECTIOUS DISEASES

IL-6 Induction and Signaling: Horizons of COVID-19-Related Pathogenesis

(2021) Tapas Patra et al.   DNA AND CELL BIOLOGY

Exosomes from COVID-19 Patients Carry Tenascin-C and Fibrinogen-β in Triggering Inflammatory Signals in Cells of Distant Organ

(2021) Subhayan Sur et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Liver injury in COVID-19 and IL-6 trans-signaling-induced endotheliopathy

(2021) Matthew J. McConnell et al.   JOURNAL OF HEPATOLOGY

The BTK inhibitor ibrutinib may protect against pulmonary injury in COVID-19–infected patients

(2020) Steven P. Treon et al.   BLOOD

Elevated Expression of Serum Endothelial Cell Adhesion Molecules in COVID-19 Patients

(2020) Ming Tong et al.   JOURNAL OF INFECTIOUS DISEASES

Inhibition of Bruton tyrosine kinase in patients with severe COVID-19

(2020) Mark Roschewski et al.   Science Immunology

SARS-CoV-2 infection pathogenesis is related to oxidative stress as a response to aggression

(2020) Rubens Cecchini et al.   MEDICAL HYPOTHESES

Acute Kidney Injury in COVID-19: The Chinese Experience

(2020) Xizi Zheng et al.   SEMINARS IN NEPHROLOGY

SARS-CoV-2 spike protein promotes IL-6 trans-signaling by activation of angiotensin II receptor signaling in epithelial cells

(2020) Tapas Patra et al.   PLoS Pathogens

The BTK inhibitor zanubrutinib (BGB-3111) demonstrated synergies with other anti-lymphoma targeted agents

(2019) Chiara Tarantelli et al.   HAEMATOLOGICA

Coronaviren als Ursache respiratorischer Infektionen

(2019) V. M. Corman et al.   INTERNIST

Cellular Senescence: Defining a Path Forward

(2019) Vassilis Gorgoulis et al.   CELL

The senescent bystander effect is caused by ROS-activated NF-κB signalling

(2018) Glyn Nelson et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Senescence Inducer Shikonin ROS-Dependently Suppressed Lung Cancer Progression

(2018) Hongming Zheng et al.   Frontiers in Pharmacology

AZD5153: A Novel Bivalent BET Bromodomain Inhibitor Highly Active against Hematologic Malignancies

(2016) G. W. Rhyasen et al.   MOLECULAR CANCER THERAPEUTICS

BRD4 Connects Enhancer Remodeling to Senescence Immune Surveillance

(2016) N. Tasdemir et al.   Cancer Discovery

Tumor-Associated Macrophages Produce Interleukin 6 and Signal via STAT3 to Promote Expansion of Human Hepatocellular Carcinoma Stem Cells

(2014) Shanshan Wan et al.   GASTROENTEROLOGY

Temporally distinct roles of ATM and ROS in genotoxic-stress-dependent induction and maintenance of cellular senescence

(2014) R. R. Nair et al.   JOURNAL OF CELL SCIENCE

The Mechanisms behind the Therapeutic Activity of BET Bromodomain Inhibition

(2014) Junwei Shi et al.   MOLECULAR CELL

BTK inhibitors in chronic lymphocytic leukemia: a glimpse to the future

(2014) M Spaargaren et al.   ONCOGENE

A senescent cell bystander effect: senescence-induced senescence

(2012) Glyn Nelson et al.   AGING CELL

The Senescence-Associated Secretory Phenotype: The Dark Side of Tumor Suppression

(2010) Jean-Philippe Coppé et al.   Annual Review of Pathology-Mechanisms of Disease