United Kingdom Biobank (UK Biobank)

Predictive Accuracy of a Polygenic Risk Score–Enhanced Prediction Model vs a Clinical Risk Score for Coronary Artery Disease

(2020) Joshua Elliott et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Large-scale Quality Control of Cardiac Imaging in Population Studies: Application to UK Biobank

(2020) Giacomo Tarroni et al.   Scientific Reports

Comparison of risk factor associations in UK Biobank against representative, general population based studies with conventional response rates: prospective cohort study and individual participant meta-analysis

(2020) G David Batty et al.   BMJ-British Medical Journal

The UK Biobank imaging enhancement of 100,000 participants: rationale, data collection, management and future directions

(2020) Thomas J. Littlejohns et al.   Nature Communications

Analysis of cardiac magnetic resonance imaging in 36,000 individuals yields genetic insights into dilated cardiomyopathy

(2020) James P. Pirruccello et al.   Nature Communications

An Outbreak of Polygenic Scores for Coronary Artery Disease

(2020) Jerome I. Rotter et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Tutorial: a guide to performing polygenic risk score analyses

(2020) Shing Wan Choi et al.   Nature Protocols

Exome sequencing and characterization of 49,960 individuals in the UK Biobank

(2020) Cristopher V. Van Hout et al.   NATURE

Polygenic background modifies penetrance of monogenic variants for tier 1 genomic conditions

(2020) Akl C. Fahed et al.   Nature Communications

Pharmacogenetics at Scale: An Analysis of the UK Biobank

(2020) Gregory McInnes et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Global Burden of Cardiovascular Diseases and Risk Factors, 1990–2019

(2020) Gregory A. Roth et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Phenotypic Refinement of Heart Failure in a National Biobank Facilitates Genetic Discovery

(2019) Krishna G. Aragam et al.   CIRCULATION

Association Between Ambient Air Pollution and Cardiac Morpho-Functional Phenotypes

(2019) Nay Aung et al.   CIRCULATION

Body mass index and body composition in relation to 14 cardiovascular conditions in UK Biobank: a Mendelian randomization study

(2019) Susanna C Larsson et al.   EUROPEAN HEART JOURNAL

ukbtools: An R package to manage and query UK Biobank data

(2019) Ken B. Hanscombe et al.   PLoS One

The advantages of UK Biobank's open‐access strategy for health research

(2019) M. Conroy et al.   JOURNAL OF INTERNAL MEDICINE

European Society of Cardiology: Cardiovascular Disease Statistics 2019

(2019) Adam Timmis et al.   EUROPEAN HEART JOURNAL

Associations of Fitness, Physical Activity, Strength, and Genetic Risk With Cardiovascular Disease

(2018) Emmi Tikkanen et al.   CIRCULATION

Cardiovascular Metabolomics

(2018) Robert W. McGarrah et al.   CIRCULATION RESEARCH

Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations

(2018) Amit V. Khera et al.   NATURE GENETICS

The UK Biobank resource with deep phenotyping and genomic data

(2018) Clare Bycroft et al.   NATURE

Genetic risk, incident stroke, and the benefits of adhering to a healthy lifestyle: cohort study of 306 473 UK Biobank participants

(2018) Loes CA Rutten-Jacobs et al.   BMJ-British Medical Journal

UK Biobank: opportunities for cardiovascular research

(2017) Thomas J. Littlejohns et al.   EUROPEAN HEART JOURNAL

Mendelian randomisation in cardiovascular research: an introduction for clinicians

(2017) Derrick A Bennett et al.   HEART

Collider scope: when selection bias can substantially influence observed associations

(2017) Marcus R Munafò et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

The impact of cardiovascular risk factors on cardiac structure and function: Insights from the UK Biobank imaging enhancement study

(2017) Steffen E. Petersen et al.   PLoS One

Application of Whole Exome Sequencing in the Clinical Diagnosis and Management of Inherited Cardiovascular Diseases in AdultsCLINICAL PERSPECTIVE

(2017) Sara B. Seidelmann et al.   Circulation-Cardiovascular Genetics

Best (but oft-forgotten) practices: the design, analysis, and interpretation of Mendelian randomization studies

(2016) Philip C Haycock et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Trends in the epidemiology of cardiovascular disease in the UK

(2016) Prachi Bhatnagar et al.   HEART

Precision medicine in cardiology

(2016) Elliott M. Antman et al.   Nature Reviews Cardiology

What matters most: quantifying an epidemiology of consequence

(2015) Katherine Keyes et al.   ANNALS OF EPIDEMIOLOGY

UK Biobank: An Open Access Resource for Identifying the Causes of a Wide Range of Complex Diseases of Middle and Old Age

(2015) Cathie Sudlow et al.   PLOS MEDICINE

Representativeness is not helpful in studying heterogeneity of effects across subgroups

(2014) K. Rothman et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Commentary: Should we always deliberately be non-representative?

(2013) S. Ebrahim et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

What makes UK Biobank special?

(2012) Rory Collins   LANCET

Current progress in pharmacogenetics

(2011) John D. Blakey et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

The Emergence of Translational Epidemiology: From Scientific Discovery to Population Health Impact

(2010) M. J. Khoury et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

The Contribution of the Framingham Heart Study to the Prevention of Cardiovascular Disease: A Global Perspective

(2010) Shanthi Mendis   PROGRESS IN CARDIOVASCULAR DISEASES