Determining The Role of Surface Glycans in The Pharmacokinetics of Small Extracellular Vesicles

Altered biodistribution of deglycosylated extracellular vesicles through enhanced cellular uptake

(2020) Nao Nishida-Aoki et al.   Journal of Extracellular Vesicles

Assessing the role of surface glycans of extracellular vesicles on cellular uptake

(2019) Charles Williams et al.   Scientific Reports

Blood concentrations of small extracellular vesicles are determined by a balance between abundant secretion and rapid clearance

(2019) Akihiro Matsumoto et al.   Journal of Extracellular Vesicles

Role of Extracellular Vesicle Surface Proteins in the Pharmacokinetics of Extracellular Vesicles

(2018) Chonlada Charoenviriyakul et al.   MOLECULAR PHARMACEUTICS

Shedding light on the cell biology of extracellular vesicles

(2018) Guillaume van Niel et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Role of Phosphatidylserine-Derived Negative Surface Charges in the Recognition and Uptake of Intravenously Injected B16BL6-Derived Exosomes by Macrophages

(2017) Akihiro Matsumoto et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Influence of Core β-1,2-Xylosylation on Glycoprotein Recognition by Murine C-type Lectin Receptors and Its Impact on Dendritic Cell Targeting

(2016) Katarzyna Brzezicka et al.   ACS Chemical Biology

Extracellular Vesicles in Cancer: Cell-to-Cell Mediators of Metastasis

(2016) Annette Becker et al.   CANCER CELL

Communication by Extracellular Vesicles: Where We Are and Where We Need to Go

(2016) Mercedes Tkach et al.   CELL

Getting to know the extracellular vesicle glycome

(2016) Jared Q. Gerlach et al.   Molecular BioSystems

Extracellular Vesicles: Composition, Biological Relevance, and Methods of Study

(2015) MikoŁaj P. Zaborowski et al.   BIOSCIENCE

Antigen presenting cell-selective drug delivery by glycan-decorated nanocarriers

(2015) Theresa Frenz et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

The Role of Glycosylation in Breast Cancer Metastasis and Cancer Control

(2015) Alexandra C. Kölbl et al.   Frontiers in Oncology

Evaluation of desialylation effect on zeta potential of extracellular vesicles secreted from human prostate cancer cells by on-chip microcapillary electrophoresis

(2014) Takanori Akagi et al.   JAPANESE JOURNAL OF APPLIED PHYSICS

ComplexN-Linked Glycans Serve as a Determinant for Exosome/Microvesicle Cargo Recruitment

(2014) Yaxuan Liang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Visualization and in vivo tracking of the exosomes of murine melanoma B16-BL6 cells in mice after intravenous injection

(2013) Yuki Takahashi et al.   JOURNAL OF BIOTECHNOLOGY

Extracellular vesicles: biology and emerging therapeutic opportunities

(2013) Samir EL Andaloussi et al.   NATURE REVIEWS DRUG DISCOVERY

Cancer cell exosomes depend on cell-surface heparan sulfate proteoglycans for their internalization and functional activity

(2013) H. C. Christianson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Treatment of Brain Inflammatory Diseases by Delivering Exosome Encapsulated Anti-inflammatory Drugs From the Nasal Region to the Brain

(2011) Xiaoying Zhuang et al.   MOLECULAR THERAPY

Delivery of siRNA to the mouse brain by systemic injection of targeted exosomes

(2011) Lydia Alvarez-Erviti et al.   NATURE BIOTECHNOLOGY

Altered chain-length and glycosylation modify the pharmacokinetics of human serum albumin

(2008) Yasunori Iwao et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Cellular Activation by Plasmid DNA in Various Macrophages in Primary Culture

(2008) Hiroyuki Yoshida et al.   JOURNAL OF PHARMACEUTICAL SCIENCES