Expanding the Tool Kit of Automated Flow Synthesis: Development of In-line Flash Chromatography Purification

Evaluation of Sponge Metal Catalysts in a Trickle Bed Reactor for the Continuous Hydrogenation of an Aliphatic Nitro Intermediate

(2020) Antonella Carangio et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Continuous-flow synthesis and application of polymer-supported BODIPY Photosensitisers for the generation of singlet oxygen; process optimised by in-line NMR spectroscopy

(2020) Christopher G. Thomson et al.   Journal of Flow Chemistry

An Autonomous Chemical Robot Discovers the Rules of Inorganic Coordination Chemistry without Prior Knowledge

(2020) Luzian Porwol et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A nanomaterials discovery robot for the Darwinian evolution of shape programmable gold nanoparticles

(2020) Daniel Salley et al.   Nature Communications

Artificial Chemist: An Autonomous Quantum Dot Synthesis Bot

(2020) Robert W. Epps et al.   ADVANCED MATERIALS

Heterogeneous photocatalysis in flow chemical reactors

(2020) Christopher G Thomson et al.   Beilstein Journal of Organic Chemistry

A mobile robotic chemist

(2020) Benjamin Burger et al.   NATURE

A Modular Programmable Inorganic Cluster Discovery Robot for the Discovery and Synthesis of Polyoxometalates

(2020) Daniel S. Salley et al.   ACS Central Science

A universal system for digitization and automatic execution of the chemical synthesis literature

(2020) S. Hessam M. Mehr et al.   SCIENCE

Additive manufacturing of intricate and inherently photocatalytic flow reactor components

(2020) Adilet Zhakeyev et al.   Additive Manufacturing

Accelerated discovery of organic polymer photocatalysts for hydrogen evolution from water through the integration of experiment and theory

(2019) Yang Bai et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Batch Versus Flow Lithiation‐Substitution of 1,3,4‐Oxadiazoles: Exploitation of Unstable Intermediates Using Flow Chemistry

(2019) Jeff Wong et al.   CHEMISTRY-A EUROPEAN JOURNAL

A robotic platform for flow synthesis of organic compounds informed by AI planning

(2019) Connor W. Coley et al.   SCIENCE

Using an Automated Monitoring Platform for Investigations of Biphasic Reactions

(2019) Jordan A. Daponte et al.   ACS Catalysis

A Facile Method for the Separation of Methionine Sulfoxide Diastereomers, Structural Assignment, and DFT Analysis

(2019) Jevgenij A. Raskatov et al.   CHEMISTRY-A EUROPEAN JOURNAL

In-Line Purification: A Key Component to Facilitate Drug Synthesis and Process Development in Medicinal Chemistry

(2019) Nopphon Weeranoppanant et al.   ACS Medicinal Chemistry Letters

Machine learning meets continuous flow chemistry: Automated optimization towards the Pareto front of multiple objectives

(2018) Artur M. Schweidtmann et al.   CHEMICAL ENGINEERING JOURNAL

Digitization of multistep organic synthesis in reactionware for on-demand pharmaceuticals

(2018) Philip J. Kitson et al.   SCIENCE

High-throughput discovery of organic cages and catenanes using computational screening fused with robotic synthesis

(2018) R. L. Greenaway et al.   Nature Communications

Catalyst Free Selective Monobenzoylation of Diols with Benzoyl Cyanide: A Robust and Regioselective Strategy

(2018) Malik Abdul Waseem et al.   ChemistrySelect

Integrating continuous flow synthesis with in-line analysis and data generation

(2018) Marcus Baumann   ORGANIC & BIOMOLECULAR CHEMISTRY

In-line separation of multicomponent reaction mixtures using a new semi-continuous supercritical fluid chromatography system

(2018) Daniel E. Fitzpatrick et al.   Reaction Chemistry & Engineering

Organic synthesis in a modular robotic system driven by a chemical programming language

(2018) Sebastian Steiner et al.   SCIENCE

The Use of Molecular Oxygen for Liquid Phase Aerobic Oxidations in Continuous Flow

(2018) Christopher A. Hone et al.   Topics in Current Chemistry

Continuous Preparation and Use of Dibromoformaldoxime as a Reactive Intermediate for the Synthesis of 3-Bromoisoxazolines

(2017) Claudio Battilocchio et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Polymer-Supported Photosensitizers for Oxidative Organic Transformations in Flow and under Visible Light Irradiation

(2017) John M. Tobin et al.   ACS Catalysis

Using Singlet Oxygen to Synthesize Natural Products and Drugs

(2016) Ashwini A. Ghogare et al.   CHEMICAL REVIEWS

Applications of Continuous-Flow Photochemistry in Organic Synthesis, Material Science, and Water Treatment

(2016) Dario Cambié et al.   CHEMICAL REVIEWS

Batch and Flow Synthesis of Disulfides by Visible-Light-Induced TiO2Photocatalysis

(2016) Cecilia Bottecchia et al.   ChemSusChem

Online quantitative mass spectrometry for the rapid adaptive optimisation of automated flow reactors

(2016) Nicholas Holmes et al.   Reaction Chemistry & Engineering

Metal-Free Photocatalytic Aerobic Oxidation of Thiols to Disulfides in Batch and Continuous-Flow

(2015) Ali Talla et al.   ADVANCED SYNTHESIS & CATALYSIS

The synthesis of active pharmaceutical ingredients (APIs) using continuous flow chemistry

(2015) Marcus Baumann et al.   Beilstein Journal of Organic Chemistry

Applying green chemistry to the photochemical route to artemisinin

(2015) Zacharias Amara et al.   Nature Chemistry

A Novel Internet-Based Reaction Monitoring, Control and Autonomous Self-Optimization Platform for Chemical Synthesis

(2015) Daniel E. Fitzpatrick et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Design and optimization of coupling a continuously operated reactor with simulated moving bed chromatography

(2014) Ju Weon Lee et al.   CHEMICAL ENGINEERING JOURNAL

The van Deemter equation: Assumptions, limits, and adjustment to modern high performance liquid chromatography

(2013) Fabrice Gritti et al.   JOURNAL OF CHROMATOGRAPHY A

Sanofi’s Solvent Selection Guide: A Step Toward More Sustainable Processes

(2013) Denis Prat et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Continuous Synthesis and Purification by Direct Coupling of a Flow Reactor with Simulated Moving-Bed Chromatography

(2012) Alexander G. O'Brien et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Regioselective, Borinic Acid-Catalyzed Monoacylation, Sulfonylation and Alkylation of Diols and Carbohydrates: Expansion of Substrate Scope and Mechanistic Studies

(2012) Doris Lee et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Flow chemistry synthesis of zolpidem, alpidem and other GABAAagonists and their biological evaluation through the use of in-line frontal affinity chromatography

(2012) Lucie Guetzoyan et al.   Chemical Science

A flow-based synthesis of Imatinib: the API of Gleevec

(2010) Mark D. Hopkin et al.   CHEMICAL COMMUNICATIONS

Design of pseudo-simulated moving bed process with multi-objective optimization for the separation of a ternary mixture: Linear isotherms

(2010) Ju Weon Lee et al.   JOURNAL OF CHROMATOGRAPHY A

Highly Efficient Synthesis of Phenols by Copper-Catalyzed Oxidative Hydroxylation of Arylboronic Acids at Room Temperature in Water

(2010) Jimin Xu et al.   ORGANIC LETTERS

Online Analysis of Flowing Streams Using Microflow HPLC

(2009) Christopher J. Welch et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT