Polymorphous Low-Grade Neuroepithelial Tumor of the Young (PLNTY): Molecular Profiling Confirms Frequent MAPK Pathway Activation

Polymorphous low-grade neuroepithelial tumor of the young: case report and review focus on the radiological features and genetic alterations

(2020) Yingqian Chen et al.   BMC Neurology

cIMPACT‐NOW update 6: new entity and diagnostic principle recommendations of the cIMPACT‐Utrecht meeting on future CNS tumor classification and grading

(2020) David N. Louis et al.   BRAIN PATHOLOGY

Malignant transformation of a polymorphous low grade neuroepithelial tumor of the young (PLNTY)

(2020) Tejus A. Bale et al.   ACTA NEUROPATHOLOGICA

Case report of the rarely described polymorphous low-grade neuroepithelial tumor of the young and comparison with oligodendroglioma

(2019) Hasan Sumdani et al.   World Neurosurgery

Plenty of calcification: imaging characterization of polymorphous low-grade neuroepithelial tumor of the young

(2019) Derek R. Johnson et al.   NEURORADIOLOGY

BRAF V600E mutant oligodendroglioma‐like tumors with chromosomal instability in adolescents and young adults

(2019) Kohei Fukuoka et al.   BRAIN PATHOLOGY

Genomic Analysis of Dysembryoplastic Neuroepithelial Tumor Spectrum Reveals a Diversity of Molecular Alterations Dysregulating the MAPK and PI3K/mTOR Pathways

(2019) Lea F Surrey et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Targeted fusion analysis can aid in the classification and treatment of pediatric glioma, ependymoma, and glioneuronal tumors

(2019) Jessica A. Lake et al.   PEDIATRIC BLOOD & CANCER

Polymorphous Low-Grade Neuroepithelial Tumor of the Young: A Case Report with Genomic Findings

(2019) V. Rohan Gupta et al.   World Neurosurgery

Novel FGFR2-INA fusion identified in two low-grade mixed neuronal-glial tumors drives oncogenesis via MAPK and PI3K/mTOR pathway activation

(2018) Payal Jain et al.   ACTA NEUROPATHOLOGICA

Development and Verification of an RNA Sequencing (RNA-Seq) Assay for the Detection of Gene Fusions in Tumors

(2018) Jennifer L. Winters et al.   JOURNAL OF MOLECULAR DIAGNOSTICS

The genetic landscape of ganglioglioma

(2018) Melike Pekmezci et al.   Acta Neuropathologica Communications

Low-grade neuroepithelial tumor: Unusual presentation in an adult without history of seizures

(2018) Giulio Riva et al.   NEUROPATHOLOGY

Novel BRAF alteration in desmoplastic infantile ganglioglioma with response to targeted therapy

(2018) Melissa M. Blessing et al.   Acta Neuropathologica Communications

Copy number alterations determined by single nucleotide polymorphism array testing in the clinical laboratory are indicative of gene fusions in pediatric cancer patients

(2017) Tracy M. Busse et al.   GENES CHROMOSOMES & CANCER

Development of a Chromosomal Microarray Test for the Detection of Abnormalities in Formalin-Fixed, Paraffin-Embedded Products of Conception Specimens

(2017) Troy J. Gliem et al.   JOURNAL OF MOLECULAR DIAGNOSTICS

Comprehensive Genomic Profiling of 282 Pediatric Low‐ and High‐Grade Gliomas Reveals Genomic Drivers, Tumor Mutational Burden, and Hypermutation Signatures

(2017) Adrienne Johnson et al.   ONCOLOGIST

Polymorphous low-grade neuroepithelial tumor of the young (PLNTY): an epileptogenic neoplasm with oligodendroglioma-like components, aberrant CD34 expression, and genetic alterations involving the MAP kinase pathway

(2016) Jason T. Huse et al.   ACTA NEUROPATHOLOGICA

Genetic alterations in uncommon low-grade neuroepithelial tumors: BRAF, FGFR1, and MYB mutations occur at high frequency and align with morphology

(2016) Ibrahim Qaddoumi et al.   ACTA NEUROPATHOLOGICA

HGVS Recommendations for the Description of Sequence Variants: 2016 Update

(2016) Johan T. den Dunnen et al.   HUMAN MUTATION

COSMIC: somatic cancer genetics at high-resolution

(2016) Simon A. Forbes et al.   NUCLEIC ACIDS RESEARCH

Fusion ofPDGFRBtoMPRIP, CPSF6, andGOLGB1in three patients with eosinophilia-associated myeloproliferative neoplasms

(2015) Nicole Naumann et al.   GENES CHROMOSOMES & CANCER

Oncogenic KIAA1549-BRAF fusion with activation of the MAPK/ERK pathway in pediatric oligodendrogliomas

(2015) Anupam Kumar et al.   Cancer Genetics

MAP-RSeq: Mayo Analysis Pipeline for RNA sequencing

(2014) Krishna R Kalari et al.   BMC BIOINFORMATICS

Chromosome Band 7q34 Deletions Resulting inKIAA1549-BRAFandFAM131B-BRAFFusions in Pediatric Low-Grade Gliomas

(2014) Jacquelyn J. Roth et al.   BRAIN PATHOLOGY

Diagnostic application of high resolution single nucleotide polymorphism array analysis for children with brain tumors

(2014) Jacquelyn J. Roth et al.   Cancer Genetics

featureCounts: an efficient general purpose program for assigning sequence reads to genomic features

(2013) Y. Liao et al.   BIOINFORMATICS

Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma

(2013) David T W Jones et al.   NATURE GENETICS

Whole-genome sequencing identifies genetic alterations in pediatric low-grade gliomas

(2013)   NATURE GENETICS

Oncogenic and drug-sensitive NTRK1 rearrangements in lung cancer

(2013) Aria Vaishnavi et al.   NATURE MEDICINE

Integrative Analysis of Complex Cancer Genomics and Clinical Profiles Using the cBioPortal

(2013) J. Gao et al.   Science Signaling

Identification of Targetable FGFR Gene Fusions in Diverse Cancers

(2013) Yi-Mi Wu et al.   Cancer Discovery

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

Integrative Genomics Viewer (IGV): high-performance genomics data visualization and exploration

(2012) H. Thorvaldsdottir et al.   BRIEFINGS IN BIOINFORMATICS

The cBio Cancer Genomics Portal: An Open Platform for Exploring Multidimensional Cancer Genomics Data: Figure 1.

(2012) Ethan Cerami et al.   Cancer Discovery

Analysis of BRAF V600E mutation in 1,320 nervous system tumors reveals high mutation frequencies in pleomorphic xanthoastrocytoma, ganglioglioma and extra-cerebellar pilocytic astrocytoma

(2011) Genevieve Schindler et al.   ACTA NEUROPATHOLOGICA

edgeR: a Bioconductor package for differential expression analysis of digital gene expression data

(2009) M. D. Robinson et al.   BIOINFORMATICS

High quality copy number and genotype data from FFPE samples using Molecular Inversion Probe (MIP) microarrays

(2009) Yuker Wang et al.   BMC Medical Genomics

Duplication of 7q34 in Pediatric Low-Grade Astrocytomas Detected by High-Density Single-Nucleotide Polymorphism-Based Genotype Arrays Results in a NovelBRAFFusion Gene

(2009) Angela J. Sievert et al.   BRAIN PATHOLOGY

Activation of the ERK/MAPK pathway: a signature genetic defect in posterior fossa pilocytic astrocytomas

(2009) Tim Forshew et al.   JOURNAL OF PATHOLOGY

Comprehensive Characterization of Genomic Aberrations in Gangliogliomas by CGH, Array-based CGH and Interphase FISH

(2008) Alexander Hoischen et al.   BRAIN PATHOLOGY

Tandem Duplication Producing a Novel OncogenicBRAFFusion Gene Defines the Majority of Pilocytic Astrocytomas

(2008) David T.W. Jones et al.   CANCER RESEARCH