Chromosome Band 7q34 Deletions Resulting inKIAA1549-BRAFandFAM131B-BRAFFusions in Pediatric Low-Grade Gliomas

Diagnostic application of high resolution single nucleotide polymorphism array analysis for children with brain tumors

(2014) Jacquelyn J. Roth et al.   Cancer Genetics

BRAF alterations in pediatric low grade gliomas and mixed neuronal–glial tumors

(2013) Efthymios Dimitriadis et al.   JOURNAL OF NEURO-ONCOLOGY

Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma

(2013) David T W Jones et al.   NATURE GENETICS

Whole-genome sequencing identifies genetic alterations in pediatric low-grade gliomas

(2013)   NATURE GENETICS

Paradoxical activation and RAF inhibitor resistance of BRAF protein kinase fusions characterizing pediatric astrocytomas

(2013) A. J. Sievert et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genomic analysis of diffuse pediatric low-grade gliomas identifies recurrent oncogenic truncating rearrangements in the transcription factor MYBL1

(2013) L. A. Ramkissoon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pathological and Molecular Advances in Pediatric Low-Grade Astrocytoma

(2012) Fausto J. Rodriguez et al.   Annual Review of Pathology-Mechanisms of Disease

Interplay among BRAF, p16, p53, and MIB1 in pediatric low-grade gliomas

(2012) C. Horbinski et al.   NEURO-ONCOLOGY

Outcome analysis of childhood pilocytic astrocytomas: a retrospective study of 148 cases at a single institution

(2012) C. Colin et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Clinical utilization of high-resolution single nucleotide polymorphism based oligonucleotide arrays in diagnostic studies of pediatric patients with solid tumors

(2012) Margaret J. Dougherty et al.   Cancer Genetics

Oncogenic FAM131B–BRAF fusion resulting from 7q34 deletion comprises an alternative mechanism of MAPK pathway activation in pilocytic astrocytoma

(2011) Huriye Cin et al.   ACTA NEUROPATHOLOGICA

MAPK pathway activation in pilocytic astrocytoma

(2011) David T. W. Jones et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

BRAF-KIAA1549 Fusion Predicts Better Clinical Outcome in Pediatric Low-Grade Astrocytoma

(2011) C. Hawkins et al.   CLINICAL CANCER RESEARCH

RAF gene fusion breakpoints in pediatric brain tumors are characterized by significant enrichment of sequence microhomology

(2011) A. R. J. Lawson et al.   GENOME RESEARCH

BRAFAlterations in Primary Glial and Glioneuronal Neoplasms of the Central Nervous System With Identification of 2 Novel KIAA1549

(2011) Alex Lin et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

RAF gene fusions are specific to pilocytic astrocytoma in a broad paediatric brain tumour cohort

(2010) Andrew R. J. Lawson et al.   ACTA NEUROPATHOLOGICA

MYB upregulation and genetic aberrations in a subset of pediatric low-grade gliomas

(2010) Ruth G. Tatevossian et al.   ACTA NEUROPATHOLOGICA

Brain Tumors: From Childhood Through Adolescence Into Adulthood

(2010) Mark W. Kieran et al.   JOURNAL OF CLINICAL ONCOLOGY

Rearrangements of the RAF kinase pathway in prostate cancer, gastric cancer and melanoma

(2010) Nallasivam Palanisamy et al.   NATURE MEDICINE

Activating mutations in BRAF characterize a spectrum of pediatric low-grade gliomas

(2010) Margaret J. Dougherty et al.   NEURO-ONCOLOGY

Combined molecular analysis of BRAF and IDH1 distinguishes pilocytic astrocytoma from diffuse astrocytoma

(2009) Andrey Korshunov et al.   ACTA NEUROPATHOLOGICA

Association of molecular alterations, including BRAF, with biology and outcome in pilocytic astrocytomas

(2009) Craig Horbinski et al.   ACTA NEUROPATHOLOGICA

Duplication of 7q34 in Pediatric Low-Grade Astrocytomas Detected by High-Density Single-Nucleotide Polymorphism-Based Genotype Arrays Results in a NovelBRAFFusion Gene

(2009) Angela J. Sievert et al.   BRAIN PATHOLOGY

Duplication of 7q34 is specific to juvenile pilocytic astrocytomas and a hallmark of cerebellar and optic pathway tumours

(2009) K Jacob et al.   BRITISH JOURNAL OF CANCER

Activation of the ERK/MAPK pathway: a signature genetic defect in posterior fossa pilocytic astrocytomas

(2009) Tim Forshew et al.   JOURNAL OF PATHOLOGY

Oncogenic RAF1 rearrangement and a novel BRAF mutation as alternatives to KIAA1549:BRAF fusion in activating the MAPK pathway in pilocytic astrocytoma

(2009) D T W Jones et al.   ONCOGENE

Tandem Duplication Producing a Novel OncogenicBRAFFusion Gene Defines the Majority of Pilocytic Astrocytomas

(2008) David T.W. Jones et al.   CANCER RESEARCH

BRAF gene duplication constitutes a mechanism of MAPK pathway activation in low-grade astrocytomas

(2008) Stefan Pfister et al.   JOURNAL OF CLINICAL INVESTIGATION

Frequent Gains at Chromosome 7q34 Involving BRAF in Pilocytic Astrocytoma

(2008) Eli E. Bar et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

High-resolution, dual-platform aCGH analysis reveals frequent HIPK2 amplification and increased expression in pilocytic astrocytomas

(2008) H Deshmukh et al.   ONCOGENE

Outcome analysis of childhood low-grade astrocytomas

(2008) Paul G. Fisher et al.   PEDIATRIC BLOOD & CANCER