IL-10 Dysregulation Underlies Chemokine Insufficiency, Delayed Macrophage Response, and Impaired Healing in Diabetic Wound

Integrated Skin Transcriptomics and Serum Multiplex Assays Reveal Novel Mechanisms of Wound Healing in Diabetic Foot Ulcers.

(2020) Georgios Theocharidis et al.   DIABETES

CCL2-mediated reversal of impaired skin wound healing in diabetic mice by normalization of neovascularization and collagen accumulation

(2019) Yuko Ishida et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

The origins and homeostasis of monocytes and tissue-resident macrophages in physiological situation

(2018) Yang Zhao et al.   JOURNAL OF CELLULAR PHYSIOLOGY

NOS3 Inhibition Confers Post-Ischemic Protection to Young and Aging White Matter Integrity by Conserving Mitochondrial Dynamics and Miro-2 Levels

(2018) Chinthasagar Bastian et al.   JOURNAL OF NEUROSCIENCE

The Role of Macrophages in Acute and Chronic Wound Healing and Interventions to Promote Pro-wound Healing Phenotypes

(2018) Paulina Krzyszczyk et al.   Frontiers in Physiology

The Role of Chemokines in Wound Healing

(2018) Anisyah Ridiandries et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The bioenergetics of inflammation: insights into obesity and type 2 diabetes

(2017) K N Keane et al.   EUROPEAN JOURNAL OF CLINICAL NUTRITION

The fate and lifespan of human monocyte subsets in steady state and systemic inflammation

(2017) Amit A. Patel et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Characterization of M1 and M2 polarization of macrophages in vascularized human dermo-epidermal skin substitutes in vivo

(2017) Agnes S. Klar et al.   PEDIATRIC SURGERY INTERNATIONAL

Anti-inflammatory effect of IL-10 mediated by metabolic reprogramming of macrophages

(2017) W. K. Eddie Ip et al.   SCIENCE

Ccl2/Ccr2 signalling recruits a distinct fetal microchimeric population that rescues delayed maternal wound healing

(2017) Mathieu Castela et al.   Nature Communications

Neutrophil killing of Staphylococcus aureus in diabetes, obesity and metabolic syndrome: a prospective cellular surveillance study

(2017) Ingrid Lea Scully et al.   Diabetology & Metabolic Syndrome

Granulocyte-Colony Stimulating Factor (G-CSF) Accelerates Wound Healing in Hemorrhagic Shock Rats by Enhancing Angiogenesis and Attenuating Apoptosis

(2017) Hong Huang et al.   MEDICAL SCIENCE MONITOR

Toll-Like Receptor Function in Acute Wounds

(2017) Lin Chen et al.   Advances in Wound Care

Perioperative high inspired oxygen fraction therapy reduces surgical site infection with Pseudomonas aeruginosa in rats

(2016) Jeffrey S. Kroin et al.   JOURNAL OF MEDICAL MICROBIOLOGY

Macrophages: A review of their role in wound healing and their therapeutic use

(2016) Robert J. Snyder et al.   WOUND REPAIR AND REGENERATION

Relative Expression of Proinflammatory and Antiinflammatory Genes Reveals Differences between Healing and Nonhealing Human Chronic Diabetic Foot Ulcers

(2015) Sina Nassiri et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

The innate immune system, toll-like receptors and dermal wound healing: A review

(2015) M.J. Portou et al.   VASCULAR PHARMACOLOGY

Pseudomonas aeruginosauses T3SS to inhibit diabetic wound healing

(2015) Josef Goldufsky et al.   WOUND REPAIR AND REGENERATION

Metabolic Reprogramming of Macrophages

(2014) Alex J. Freemerman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Monocyte to Macrophage Transition in the Murine Sterile Wound

(2014) Meredith J. Crane et al.   PLoS One

Pro-Inflammatory Chemokine CCL2 (MCP-1) Promotes Healing in Diabetic Wounds by Restoring the Macrophage Response

(2014) Stephen Wood et al.   PLoS One

Toll-Like Receptor Signaling Pathways

(2014) Takumi Kawasaki et al.   Frontiers in Immunology

Critical role of TXNIP in oxidative stress, DNA damage and retinal pericyte apoptosis under high glucose: Implications for diabetic retinopathy

(2013) Takhellambam S. Devi et al.   EXPERIMENTAL CELL RESEARCH

High glucose-induced oxidative stress promotes autophagy through mitochondrial damage in rat notochordal cells

(2013) Eun-Young Park et al.   INTERNATIONAL ORTHOPAEDICS

TLR4, rather than TLR2, regulates wound healing through TGF-β and CCL5 expression

(2013) Hiraku Suga et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

Amelioration in wound healing in diabetic toll-like receptor-4 knockout mice

(2013) Mohan R. Dasu et al.   JOURNAL OF DIABETES AND ITS COMPLICATIONS

Negative regulation of Toll-like receptor 4 signaling by IL-10-dependent microRNA-146b

(2013) G. Curtale et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Elastin signaling in wound repair

(2012) Jessica F. Almine et al.   BIRTH DEFECTS RESEARCH PART C-EMBRYO TODAY-REVIEWS

A Lineage of Myeloid Cells Independent of Myb and Hematopoietic Stem Cells

(2012) C. Schulz et al.   SCIENCE

Regulation of Macrophage Polarization and Wound Healing

(2012) Christopher J. Ferrante et al.   Advances in Wound Care

Generation of Mature Murine Monocytes from Heterogeneous Bone Marrow and Description of Their Properties

(2011) Alexander Francke et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

Impaired Wound Healing with Defective Expression of Chemokines and Recruitment of Myeloid Cells in TLR3-Deficient Mice

(2011) Q. Lin et al.   JOURNAL OF IMMUNOLOGY

Increased Toll-Like Receptor (TLR) Activation and TLR Ligands in Recently Diagnosed Type 2 Diabetic Subjects

(2010) M. R. Dasu et al.   DIABETES CARE

Differential Roles of Macrophages in Diverse Phases of Skin Repair

(2010) T. Lucas et al.   JOURNAL OF IMMUNOLOGY

TLR2 expression and signaling-dependent inflammation impair wound healing in diabetic mice

(2010) Mohan R Dasu et al.   LABORATORY INVESTIGATION

Accelerated wound healing mediated by activation of Toll-like receptor 9

(2010) Takashi Sato et al.   WOUND REPAIR AND REGENERATION

The role of surgical debridement in healing of diabetic foot ulcers

(2010) Elizabeth Lebrun et al.   WOUND REPAIR AND REGENERATION

Selective and Specific Macrophage Ablation Is Detrimental to Wound Healing in Mice

(2009) Rita Mirza et al.   AMERICAN JOURNAL OF PATHOLOGY

A Transgenic Mouse Model of Inducible Macrophage Depletion

(2009) Itamar Goren et al.   AMERICAN JOURNAL OF PATHOLOGY

Tissue-specific glucose toxicity induces mitochondrial damage in a burn injury model of critical illness

(2009) Ilse Vanhorebeek et al.   CRITICAL CARE MEDICINE

The phenotype of murine wound macrophages

(2009) Jean M. Daley et al.   JOURNAL OF LEUKOCYTE BIOLOGY

N-acetylcysteine prevents glucose/glucose oxidase-induced oxidative stress, mitochondrial damage and apoptosis in H9c2 cells

(2009) Santosh Kumar et al.   LIFE SCIENCES

Serial surgical debridement: A retrospective study on clinical outcomes in chronic lower extremity wounds

(2009) Matthew Cardinal et al.   WOUND REPAIR AND REGENERATION

Human skin wounds: A major and snowballing threat to public health and the economy

(2009) Chandan K. Sen et al.   WOUND REPAIR AND REGENERATION

Defects in Innate Immunity Predispose C57BL/6J-Leprdb/Leprdb Mice to Infection by Staphylococcus aureus

(2008) S. Park et al.   INFECTION AND IMMUNITY

Toll-like receptors, wound healing, and carcinogenesis

(2008) Johannes Kluwe et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Operative Debridement of Diabetic Foot Ulcers

(2008) Michael S. Golinko et al.   JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS

The chemokine receptors CCR2 and CX3CR1 mediate monocyte/macrophage trafficking in kidney ischemia–reperfusion injury

(2008) Li Li et al.   KIDNEY INTERNATIONAL

Regulation of scar formation by vascular endothelial growth factor

(2008) Traci A Wilgus et al.   LABORATORY INVESTIGATION

Post-transcriptional regulation of adapter molecules by IL-10 inhibits TLR-mediated activation of antigen-presenting cells

(2008) A Knödler et al.   LEUKEMIA

Why chronic wounds will not heal: a novel hypothesis

(2007) Thomas Bjarnsholt et al.   WOUND REPAIR AND REGENERATION