The interaction of the severe acute respiratory syndrome coronavirus 2 spike protein with drug-inhibited angiotensin converting enzyme 2 studied by molecular dynamics simulation

Angiotensin receptor blockers as tentative SARS‐CoV‐2 therapeutics

(2020) David Gurwitz   DRUG DEVELOPMENT RESEARCH

The continuing 2019-nCoV epidemic threat of novel coronaviruses to global health — The latest 2019 novel coronavirus outbreak in Wuhan, China

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Characteristics of and Important Lessons From the Coronavirus Disease 2019 (COVID-19) Outbreak in China

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Receptor recognition by novel coronavirus from Wuhan: An analysis based on decade-long structural studies of SARS

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A Novel Coronavirus from Patients with Pneumonia in China, 2019

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Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation

(2020) Daniel Wrapp et al.   SCIENCE

The species Severe acute respiratory syndrome-related coronavirus: classifying 2019-nCoV and naming it SARS-CoV-2

(2020)   Nature Microbiology

Analysis of therapeutic targets for SARS-CoV-2 and discovery of potential drugs by computational methods

(2020) Canrong Wu et al.   Acta Pharmaceutica Sinica B

Hypertension and COVID-19

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Hypertension, the renin–angiotensin system, and the risk of lower respiratory tract infections and lung injury: implications for COVID-19

(2020) Reinhold Kreutz et al.   CARDIOVASCULAR RESEARCH

Structural and Functional Basis of SARS-CoV-2 Entry by Using Human ACE2

(2020) Qihui Wang et al.   CELL

Structure, Function, and Antigenicity of the SARS-CoV-2 Spike Glycoprotein

(2020) Alexandra C. Walls et al.   CELL

SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor

(2020) Markus Hoffmann et al.   CELL

Clinical Features of 69 Cases With Coronavirus Disease 2019 in Wuhan, China

(2020) Zhongliang Wang et al.   CLINICAL INFECTIOUS DISEASES

Probable Pangolin Origin of SARS-CoV-2 Associated with the COVID-19 Outbreak

(2020) Tao Zhang et al.   CURRENT BIOLOGY

Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study

(2020) Fei Zhou et al.   LANCET

Clinical features and obstetric and neonatal outcomes of pregnant patients with COVID-19 in Wuhan, China: a retrospective, single-centre, descriptive study

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Structural basis of receptor recognition by SARS-CoV-2

(2020) Jian Shang et al.   NATURE

The proximal origin of SARS-CoV-2

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Phylogenetic network analysis of SARS-CoV-2 genomes

(2020) Peter Forster et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Risk Factors Associated With Acute Respiratory Distress Syndrome and Death in Patients With Coronavirus Disease 2019 Pneumonia in Wuhan, China

(2020) Chaomin Wu et al.   JAMA Internal Medicine

Association of hypertension and antihypertensive treatment with COVID-19 mortality: a retrospective observational study

(2020) Chao Gao et al.   EUROPEAN HEART JOURNAL

Clinical and virological data of the first cases of COVID-19 in Europe: a case series

(2020) Francois-Xavier Lescure et al.   LANCET INFECTIOUS DISEASES

Proteolytic Cleavage of the SARS-CoV-2 Spike Protein and the Role of the Novel S1/S2 Site

(2020) Javier A. Jaimes et al.   iScience

SARS-CoV-2 immunity: review and applications to phase 3 vaccine candidates

(2020) Gregory A Poland et al.   LANCET

Counter-regulatory renin–angiotensin system in cardiovascular disease

(2019) Maria Paz Ocaranza et al.   Nature Reviews Cardiology

Large-scale prediction of binding affinity in protein-small ligand complexes: the PRODIGY-LIG web server

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Angiotensin converting enzyme versus angiotensin converting enzyme-2 selectivity of MLN-4760 and DX600 in human and murine bone marrow-derived cells

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Urinary Angiotensin-Converting Enzyme 2 in Hypertensive Patients May Be Increased by Olmesartan, an Angiotensin II Receptor Blocker

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STAT3 Signaling Is Activated Preferentially in Tumor-Initiating Cells in Claudin-Low Models of Human Breast Cancer

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Identification of prolyl carboxypeptidase as an alternative enzyme for processing of renal angiotensin II using mass spectrometry

(2013) Nadja Grobe et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Murine Recombinant Angiotensin-Converting Enzyme 2

(2012) Minghao Ye et al.   HYPERTENSION

Optimization of the Additive CHARMM All-Atom Protein Force Field Targeting Improved Sampling of the Backbone ϕ, ψ and Side-Chain χ1 and χ2 Dihedral Angles

(2012) Robert B. Best et al.   Journal of Chemical Theory and Computation

Inhibition of Angiotensin-Converting Enzyme 2 Exacerbates Cardiac Hypertrophy and Fibrosis in Ren-2 Hypertensive Rats

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Genetic Ace2 Deficiency Accentuates Vascular Inflammation and Atherosclerosis in the ApoE Knockout Mouse

(2010) Merlin C. Thomas et al.   CIRCULATION RESEARCH

Effects of the ACE2 inhibitor GL1001 on acute dextran sodium sulfate-induced colitis in mice

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Mechanical properties of physiological and pathological models of collagen peptides investigated via steered molecular dynamics simulations

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