Transcriptional Characteristics of IDH-Wild Type Glioma Subgroups Highlight the Biological Processes Underlying Heterogeneity of IDH-Wild Type WHO Grade IV Gliomas

Dual functionalized brain-targeting nanoinhibitors restrain temozolomide-resistant glioma via attenuating EGFR and MET signaling pathways

(2020) Xiangqi Meng et al.   Nature Communications

Heterogeneity of response to immune checkpoint blockade in hypermutated experimental gliomas

(2020) Katrin Aslan et al.   Nature Communications

Classification of diffuse lower‐grade glioma based on immunological profiling

(2020) Fan Wu et al.   Molecular Oncology

The molecular characteristics of spinal cord gliomas with or without H3 K27M mutation

(2020) Rui-Chao Chai et al.   Acta Neuropathologica Communications

Molecular profiling of an osseous metastasis in glioblastoma during checkpoint inhibition: potential mechanisms of immune escape

(2020) Malte Mohme et al.   Acta Neuropathologica Communications

DNA damage repair alterations modulate M2 polarization of microglia to remodel the tumor microenvironment via the p53-mediated MDK expression in glioma

(2019) Xiangqi Meng et al.   EBioMedicine

m6A RNA methylation regulators contribute to malignant progression and have clinical prognostic impact in gliomas

(2019) Rui-Chao Chai et al.   Aging-US

Inflammatory Breast Cancer Promotes Development of M2 Tumor-associated Macrophages and Cancer Mesenchymal Cells Through a Complex Cytokine Network

(2019) Amanda Valeta-Magara et al.   CANCER RESEARCH

Systematically characterize the clinical and biological significances of 1p19q genes in 1p/19q non-codeletion glioma

(2019) Rui-Chao Chai et al.   CARCINOGENESIS

Metascape provides a biologist-oriented resource for the analysis of systems-level datasets

(2019) Yingyao Zhou et al.   Nature Communications

A Novel DNA Methylation-Based Signature Can Predict the Responses of MGMT Promoter Unmethylated Glioblastomas to Temozolomide

(2019) Rui-Chao Chai et al.   Frontiers in Genetics

Predominance of M2 macrophages in gliomas leads to the suppression of local and systemic immunity

(2019) Aurobind Vidyarthi et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Immune landscapes associated with different glioblastoma molecular subtypes

(2019) Maria Martinez-Lage et al.   Acta Neuropathologica Communications

A Glial Signature and Wnt7 Signaling Regulate Glioma-Vascular Interactions and Tumor Microenvironment

(2018) Amelie Griveau et al.   CANCER CELL

LYG-202 inhibits activation of endothelial cells and angiogenesis through CXCL12/CXCR7 pathway in breast cancer

(2018) Kai Zhao et al.   CARCINOGENESIS

Expression-based intrinsic glioma subtypes are prognostic in low-grade gliomas of the EORTC22033-26033 clinical trial

(2018) Y. Gao et al.   EUROPEAN JOURNAL OF CANCER

Glioma infiltration and extracellular matrix: key players and modulators

(2018) Valéria Pereira Ferrer et al.   GLIA

A novel gene signature based on five glioblastoma stem-like cell relevant genes predicts the survival of primary glioblastoma

(2018) Ruichao Chai et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Immune heterogeneity and clinicopathologic characterization of IGFBP2 in 2447 glioma samples

(2018) Jinquan Cai et al.   OncoImmunology

Association of MGMT Promoter Methylation Status With Survival Outcomes in Patients With High-Risk Glioma Treated With Radiotherapy and Temozolomide

(2018) Erica H. Bell et al.   JAMA Oncology

cIMPACT-NOW update 3: recommended diagnostic criteria for “Diffuse astrocytic glioma, IDH-wildtype, with molecular features of glioblastoma, WHO grade IV”

(2018) Daniel J. Brat et al.   ACTA NEUROPATHOLOGICA

Mutational Landscape of Secondary Glioblastoma Guides MET-Targeted Trial in Brain Tumor

(2018) Huimin Hu et al.   CELL

A novel analytical model of MGMT methylation pyrosequencing offers improved predictive performance in patients with gliomas

(2018) Rui-Chao Chai et al.   MODERN PATHOLOGY

Detailed longitudinal sampling of glioma stem cells in situ reveals Chr7 gain and Chr10 loss as repeated events in primary tumor formation and recurrence

(2017) Mehmet Baysan et al.   INTERNATIONAL JOURNAL OF CANCER

Emerging functions of the EGFR in cancer

(2017) Sara Sigismund et al.   Molecular Oncology

Adult IDH wild-type lower-grade gliomas should be further stratified

(2017) Abudumijit Aibaidula et al.   NEURO-ONCOLOGY

CGCG clinical practice guidelines for the management of adult diffuse gliomas

(2016) Tao Jiang et al.   CANCER LETTERS

Molecular Profiling Reveals Biologically Discrete Subsets and Pathways of Progression in Diffuse Glioma

(2016) Michele Ceccarelli et al.   CELL

Classification based on mutations ofTERTpromoter andIDHcharacterizes subtypes in grade II/III gliomas

(2016) Pei Yang et al.   NEURO-ONCOLOGY

Immune Checkpoint Blockade: A Common Denominator Approach to Cancer Therapy

(2015) Suzanne L. Topalian et al.   CANCER CELL

Robust enumeration of cell subsets from tissue expression profiles

(2015) Aaron M Newman et al.   NATURE METHODS

Remodelling the extracellular matrix in development and disease

(2014) Caroline Bonnans et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

A glioma classification scheme based on coexpression modules of EGFR and PDGFRA

(2014) Yingyu Sun et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neutrophils Promote the Malignant Glioma Phenotype through S100A4

(2013) J. Liang et al.   CLINICAL CANCER RESEARCH

TERT promoter mutations occur frequently in gliomas and a subset of tumors derived from cells with low rates of self-renewal

(2013) P. J. Killela et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Why don't we get more cancer? A proposed role of the microenvironment in restraining cancer progression

(2011) Mina J Bissell et al.   NATURE MEDICINE

Immunotherapy in gliomas: limitations and potential of natural killer (NK) cell therapy

(2011) Henry Ogbomo et al.   TRENDS IN MOLECULAR MEDICINE

Integrated Genomic Analysis Identifies Clinically Relevant Subtypes of Glioblastoma Characterized by Abnormalities in PDGFRA, IDH1, EGFR, and NF1

(2010) Roel G.W. Verhaak et al.   CANCER CELL

IDH1andIDH2Mutations in Gliomas

(2009) Hai Yan et al.   NEW ENGLAND JOURNAL OF MEDICINE

Possible involvement of the M2 anti-inflammatory macrophage phenotype in growth of human gliomas

(2008) Y Komohara et al.   JOURNAL OF PATHOLOGY