Chronic T cell proliferation in brains after stroke could interfere with the efficacy of immunotherapies

Natalizumab in acute ischemic stroke (ACTION II): a randomized, placebo-controlled trial

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In vivo widefield calcium imaging of the mouse cortex for analysis of network connectivity in health and brain disease

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Short-Chain Fatty Acids Improve Poststroke Recovery via Immunological Mechanisms

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Microglia monitor and protect neuronal function through specialized somatic purinergic junctions

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T cells in the post-ischemic brain: Troopers or paramedics?

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Safety and efficacy of natalizumab in patients with acute ischaemic stroke (ACTION): a randomised, placebo-controlled, double-blind phase 2 trial

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Direct comparison of microglial dynamics and inflammatory profile in photothrombotic and arterial occlusion evoked stroke

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B-Lymphocyte-Mediated Delayed Cognitive Impairment following Stroke

(2015) K. P. Doyle et al.   JOURNAL OF NEUROSCIENCE

Results of a preclinical randomized controlled multicenter trial (pRCT): Anti-CD49d treatment for acute brain ischemia

(2015) Gemma Llovera et al.   Science Translational Medicine

Very-late-antigen-4 (VLA-4)-mediated brain invasion by neutrophils leads to interactions with microglia, increased ischemic injury and impaired behavior in experimental stroke

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Biomedical research: increasing value, reducing waste

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Effect of treatment delay, age, and stroke severity on the effects of intravenous thrombolysis with alteplase for acute ischaemic stroke: a meta-analysis of individual patient data from randomised trials

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Thy1-GCaMP6 Transgenic Mice for Neuronal Population Imaging In Vivo

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Blocking of α4 Integrin Does Not Protect From Acute Ischemic Stroke in Mice

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Modeling Stroke in Mice: Permanent Coagulation of the Distal Middle Cerebral Artery

(2014) Gemma Llovera et al.   Jove-Journal of Visualized Experiments

Bringing rigour to translational medicine

(2013) David W. Howells et al.   Nature Reviews Neurology

Postischemic Brain Infiltration of Leukocyte Subpopulations Differs among Murine Permanent and Transient Focal Cerebral Ischemia Models

(2012) Wei Zhou et al.   BRAIN PATHOLOGY

Targeting Mannose-Binding Lectin Confers Long-Lasting Protection With a Surprisingly Wide Therapeutic Window in Cerebral Ischemia

(2012) Franca Orsini et al.   CIRCULATION

The immunology of acute stroke

(2012) Ángel Chamorro et al.   Nature Reviews Neurology

Inhibition of lymphocyte trafficking shields the brain against deleterious neuroinflammation after stroke

(2011) Arthur Liesz et al.   BRAIN

Stroke and the immune system: from pathophysiology to new therapeutic strategies

(2011) Richard Macrez et al.   LANCET NEUROLOGY

The immunology of stroke: from mechanisms to translation

(2011) Costantino Iadecola et al.   NATURE MEDICINE

The Science of Stroke: Mechanisms in Search of Treatments

(2010) Michael A. Moskowitz et al.   NEURON

Improving Bioscience Research Reporting: The ARRIVE Guidelines for Reporting Animal Research

(2010) Carol Kilkenny et al.   PLOS BIOLOGY

Regulatory T cells are key cerebroprotective immunomodulators in acute experimental stroke

(2009) Arthur Liesz et al.   NATURE MEDICINE

Improving Outcome after Stroke: Overcoming the Translational Roadblock

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Thrombolysis with Alteplase 3 to 4.5 Hours after Acute Ischemic Stroke

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